Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Melissa A. Kovach"'
Autor:
Melissa A. Kovach, Ulrika Käck, Karlhans F Che, Bettina Brundin, Jon R. Konradsen, Anders Lindén
Publikováno v:
Respiratory Research, Vol 25, Iss 1, Pp 1-11 (2024)
Abstract Background Interleukin (IL)-26 is produced by T helper type 17 (Type 17) cells and exerts immunomodulatory plus antimicrobial effects. Previous studies show that local IL-26 concentrations in the airways are higher in patients with uncontrol
Externí odkaz:
https://doaj.org/article/546e097d907c490c9815d6725b2f38fa
Autor:
Nikolaos, Pournaras, Anders, Andersson, Melissa A, Kovach, Médea, Padra, Karlhans F, Che, Bettina, Brundin, Shigemi, Yoshihara, Steven, Bozinovski, Sara K, Lindén, Per-Anders, Jansson, Magnus C, Sköld, Ingemar, Qvarfordt, Anders, Lindén
Publikováno v:
International journal of chronic obstructive pulmonary disease. 17
Type 2 diabetes mellitus (T2DM) and metabolic syndrome (MetS) are common comorbidities in chronic obstructive pulmonary disease (COPD), but the underlying pathogenic mechanisms are poorly understood. Given that these morbidities all display increased
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::957866c3fdb7e12be8b4a13ee99ce743
https://pubmed.ncbi.nlm.nih.gov/35620349
https://pubmed.ncbi.nlm.nih.gov/35620349
Autor:
Urvashi Bhan, Amy B Podsiad, Melissa A Kovach, Megan N Ballinger, Venkateshwar Keshamouni, Theodore J Standiford
Publikováno v:
PLoS ONE, Vol 10, Iss 1, p e0114574 (2015)
INTRODUCTION:Post influenza pneumonia is a leading cause of mortality and morbidity, with mortality rates approaching 60% when bacterial infections are secondary to multi-drug resistant (MDR) pathogens. Staphylococcus aureus, in particular community
Externí odkaz:
https://doaj.org/article/162970e7e382402fa2d7011be722a3dc
Autor:
Giovanny J. Martínez-Colón, Melissa A. Kovach, Steven L. Kunkel, Benjamin H. Singer, Bethany B. Moore, Thomas A. Moore, Theodore J. Standiford, Michael W. Newstead, Peter Mancuso, Marc Peters-Golden, Xianying Zeng
Publikováno v:
Mucosal Immunology
Interleukin-36γ (IL-36γ) is a member of novel IL-1-like proinflammatory cytokine family that are highly expressed in epithelial tissues and several myeloid-derived cell types. Little is known about the role of the IL-36 family in mucosal immunity,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4417af2923cf7b64bd7133ad72767b8e
https://doi.org/10.1038/mi.2016.130
https://doi.org/10.1038/mi.2016.130
Autor:
Michael W. Newstead, Leslie B. Tolle, Gabriel Núñez, Fushin X Yu, Theodore J. Standiford, Melissa A. Kovach, Megan N. Ballinger, Xianying Zeng
Publikováno v:
Journal of Innate Immunity. 7:177-186
Flagellin is the major structural component of flagella expressed by Pseudomonas aeruginosa (PA) and other bacteria. This protein has been shown to activate the Toll-like receptor TLR5 and the Nod-like receptor Nlrc4/Ipaf, culminating in the expressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e694d3312d34f32b2725c7988d75b1e1
https://doi.org/10.1159/000367790
https://doi.org/10.1159/000367790
Publikováno v:
Current Opinion in Infectious Diseases. 25:321-327
PURPOSE OF REVIEW Neutrophils are an essential arm of the innate immune response. In patients with sepsis, reprogramming of neutrophil occurs, manifest by impaired recruitment of neutrophils to sites of infection, abnormal accumulation of neutrophils
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fea18d64c68037bf3f1705ab71ff7bc
https://doi.org/10.1097/qco.0b013e3283528c9b
https://doi.org/10.1097/qco.0b013e3283528c9b
Autor:
Michael J. Newstead, Ajaya Kumar Reka, Louis R. Standiford, Megan N. Ballinger, Xianying Zeng, Theodore J. Standiford, Urvashi Bhan, Melissa A. Kovach
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 302:L447-L454
Toll-like receptors (TLRs) are required for protective host defense against bacterial pathogens. However, the role of TLRs in regulating lung injury during Gram-negative bacterial pneumonia has not been thoroughly investigated. In this study, experim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3abfc05963f2c717e87ab35129e41c46
https://doi.org/10.1152/ajplung.00415.2010
https://doi.org/10.1152/ajplung.00415.2010
Autor:
Melissa A. Kovach, Michael W. Newstead, Eric S. White, Steven L. Kunkel, Marc Peters-Golden, Thomas A. Moore, Benjamin H. Singer, Theodore J. Standiford, Xianying Zeng
Publikováno v:
Journal of leukocyte biology. 100(2)
Interleukin-36 is a family of novel interleukin-1-like proinflammatory cytokines that are highly expressed in epithelial tissues and several myeloid-derived cell types. Like those of classic interleukin-1 cytokines, the secretion mechanisms of interl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9294747d8d1ef4f8cdc337030c02360
https://pubmed.ncbi.nlm.nih.gov/26864267
https://pubmed.ncbi.nlm.nih.gov/26864267
Autor:
Jonathan R. Traynor, Steven F. Bolling, William C. Claycomb, Shu Yung James Wu, Matthew A. Romano, Melissa A. Kovach, E.M. Seymour
Publikováno v:
Journal of Surgical Research. 114:187-194
Background Opioid preconditioning protects the myocardium against ischemia/reperfusion (IR) injury. By enhancing cardiomyocyte viability, opioids can enhance cardiac function and recovery from IR injury during acute cardiac care. The myocyte model HL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::08ffd4f3e87ce58b05fb3aaf81046b98
https://doi.org/10.1016/s0022-4804(03)00248-8
https://doi.org/10.1016/s0022-4804(03)00248-8
Autor:
Amy B. Podsiad, Urvashi Bhan, Theodore J. Standiford, Venkateshwar G. Keshamouni, Megan N. Ballinger, Melissa A. Kovach
Publikováno v:
PLoS ONE
PLoS ONE, Vol 10, Iss 1, p e0114574 (2015)
PLoS ONE, Vol 10, Iss 1, p e0114574 (2015)
Introduction Post influenza pneumonia is a leading cause of mortality and morbidity, with mortality rates approaching 60% when bacterial infections are secondary to multi-drug resistant (MDR) pathogens. Staphylococcus aureus, in particular community
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e49f916e9bd8a73ccdb70039bae66ca
https://pubmed.ncbi.nlm.nih.gov/25635685
https://pubmed.ncbi.nlm.nih.gov/25635685