Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Melissa A Nashat"'
Evaluating possible maternal effect lethality and genetic background effects in Naa10 knockout mice.
Autor:
Gholson J Lyon, Joseph Longo, Andrew Garcia, Fatima Inusa, Elaine Marchi, Daniel Shi, Max Dörfel, Thomas Arnesen, Rafael Aldabe, Scott Lyons, Melissa A Nashat, David Bolton
Publikováno v:
PLoS ONE, Vol 19, Iss 5, p e0301328 (2024)
Amino-terminal (Nt-) acetylation (NTA) is a common protein modification, affecting approximately 80% of all human proteins. The human essential X-linked gene, NAA10, encodes for the enzyme NAA10, which is the catalytic subunit in the N-terminal acety
Externí odkaz:
https://doaj.org/article/034d7ff7dd2344d2beb10b3185c4e599
Autor:
Neil S. Lipman, Robert S Livingston, Rodolfo J Ricart Arbona, Michelle L Lepherd, Melissa A Nashat, Sara F Santagostino, Elyn Riedel
Publikováno v:
Journal of the American Association for Laboratory Animal Science. 57:483-497
Demodex musculi is a prostigmatid follicular mite that has rarely been reported in laboratory mice. Although prevalence of this species has not been assessed formally, we have found that many imported mouse strains from noncommercial sources harbor D
Autor:
Julie R. White, Rodolfo J Ricart Arbona, Sara F Santagostino, Melissa A Nashat, Sebastien Monette
Publikováno v:
Veterinary Pathology. 54:855-869
In the past decade, NOD.Cg- Prkdcscid Il2rgtm1Wjl/SzJ (NSG, NOD scid gamma) mice have become a model of choice in several areas of biomedical research; however, comprehensive data on their spontaneous age-related pathology are not currently available
Autor:
Melissa A, Nashat, Rodolfo J, Ricart Arbona, Michelle L, Lepherd, Sara F, Santagostino, Robert S, Livingston, Elyn R, Riedel, Neil S, Lipman
Publikováno v:
Journal of the American Association for Laboratory Animal Science : JAALAS. 57(5)
Demodex musculi is a prostigmatid follicular mite that has rarely been reported in laboratory mice. Although prevalence of this species has not been assessed formally, we have found that many imported mouse strains from noncommercial sources harbor D
Autor:
Melissa A, Nashat, Kerith R, Luchins, Michelle L, Lepherd, Elyn R, Riedel, Joanna N, Izdebska, Neil S, Lipman
Publikováno v:
Comparative medicine. 67(4)
A colony of B6.Cg-Rag1tm1Mom Tyrp1B-w Tg(Tcra,Tcrb)9Rest (TRP1/TCR) mice presented with ocular lesions and ulcerative dermatitis. Histopathology, skin scrapes, and fur plucks confirmed the presence of Demodex spp. in all clinically affected and subcl
Autor:
Melissa A. Nashat
Publikováno v:
Veterinary Parasitology. 245:168-169
Autor:
Jack P. Antel, Qiao Ling Cui, Melissa Cosenza-Nashat, Daniela Krause, Namjong Choi, Sunhee C. Lee, Leonid Tarassishin, Meng Liang Zhao, Hyeon Sook Suh, Avital Bauman, Bryce A. Durafourt
Publikováno v:
The American Journal of Pathology. 179:1360-1372
Tryptophan metabolism by the kynurenine pathway (KP) is important to the pathogenesis of inflammatory, infectious, and degenerative diseases. The 3-hydroxykynurenine (3-HK) branch of the KP is activated in macrophages and microglia, leading to the ge
Cannabinoid receptor expression in HIV encephalitis and HIV-associated neuropathologic comorbidities
Autor:
Sunhee C. Lee, Meng-Liang Zhao, Avital Bauman, Hyeon-Sook Suh, Susan Morgello, Melissa Cosenza-Nashat
Publikováno v:
Neuropathology and Applied Neurobiology. 37:464-483
Aims Cannabinoids have been proposed for treating various neurodegenerative disorders and as adjunct therapy for HIV+ patients with neurologic sequelae. The expression of cannabinoid receptors (CB1 and CB2) has been reported in neurodegenerative dise
Autor:
Namjong Choi, Harris Goldstein, Sunhee C. Lee, Hyeon Sook Suh, Melissa Cosenza-Nashat, Randy L. Jirtle, Jeffrey W. Pollard, Meng Liang Zhao, Jiu Feng Li
Publikováno v:
The American Journal of Pathology. 177:2446-2458
Insulin-like growth factor 2 receptor (IGF2R), also known as cation-independent mannose 6-phosphate (M6P) receptor, is a transmembrane glycoprotein localized in the trans-Golgi region and is involved in targeting both M6P-bearing enzymes and IGF2 to
Autor:
Sunhee C. Lee, Hyeon-Sook Suh, Susan Morgello, Ryan Natividad, Meng-Liang Zhao, Janet Morgan, Melissa Cosenza-Nashat
Publikováno v:
Neuropathology and Applied Neurobiology. 35:306-328
Aims: Microglia are involved in neurodegeneration, are prime targets for anti-inflammatory therapy and are potential biomarkers of disease progression. For example, positron emission tomography imaging employing radioligands for the mitochondrial tra