Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Melissa A Curtis"'
Autor:
Jennifer Nguyen, Melissa A. Curtis, Ali S. Imami, William G. Ryan, Khaled Alganem, Kari L. Neifer, Nilanjana Saferin, Charlotte N. Nawor, Brian P. Kistler, Gary W. Miller, Rammohan Shukla, Robert E. McCullumsmith
Publikováno v:
Translation, Vol 12, Iss 3 (2024)
Externí odkaz:
https://doaj.org/article/19421693822744e0944eb21064314f3a
Autor:
W. Katherine Tan, Brian D. Segal, Melissa D. Curtis, Shrujal S. Baxi, William B. Capra, Elizabeth Garrett-Mayer, Brian P. Hobbs, David S. Hong, Rebecca A. Hubbard, Jiawen Zhu, Somnath Sarkar, Meghna Samant
Publikováno v:
Contemporary Clinical Trials Communications, Vol 30, Iss , Pp 101000- (2022)
Background: Hybrid controlled trials with real-world data (RWD), where the control arm is composed of both trial and real-world patients, could facilitate research when the feasibility of randomized controlled trials (RCTs) is challenging and single-
Externí odkaz:
https://doaj.org/article/55c43bce2efa4cd8a8dc5818e59052f3
Autor:
Erin E. Koffman, Charles M. Kruse, Kritika Singh, Farzaneh Sadat Naghavi, Melissa A. Curtis, Jennifer Egbo, Mark Houdi, Boren Lin, Hui Lu, Jacek Debiec, Jianyang Du
Publikováno v:
JCI Insight, Vol 7, Iss 4 (2022)
Recent research on altering threat memory has focused on a reconsolidation window. During reconsolidation, threat memories are retrieved and become labile. Reconsolidation of distinct threat memories is synapse dependent, whereas the underlying regul
Externí odkaz:
https://doaj.org/article/b055948834654f299b49e01c57409aa0
Autor:
Melissa A Curtis, Rohan K Dhamsania, Rachel C Branco, Ji-Dong Guo, Justin Creeden, Kari L Neifer, Carlie A Black, Emily J Winokur, Elissar Andari, Brian G Dias, Robert C Liu, Shannon L Gourley, Gary W Miller, James P Burkett
Publikováno v:
PNAS Nexus. 2
Neurodevelopmental disorders (NDDs) are a widespread and growing public health challenge, affecting as many as 17% of children in the United States. Recent epidemiological studies have implicated ambient exposure to pyrethroid pesticides during pregn
Autor:
William B. Capra, Brian D. Segal, Lawrence Bellomo, Katherine Tan, Rebecca A. Miksad, Carrie Bennette, Nate Nussbaum, Jonathan Bryan, Aracelis Z. Torres, Melisa Tucker, Melissa D. Curtis
Publikováno v:
Clinical Pharmacology & Therapeutics. 111:168-178
Electronic health record (EHR)-derived real-world data (RWD) can be sourced to create external comparator cohorts to oncology clinical trials. This exploratory study assessed whether EHR-derived patient cohorts could emulate select clinical trial con
Publikováno v:
Journal of Clinical Oncology. 40:124-124
124 Background: Biomarker testing for EGFR mutations (EGFRm) is recommended for all newly diagnosed patients with metastatic NSCLC. Third-generation EGFR TKIs are the recommended standard-of-care therapy for patients with EGFRm+ NSCLC regardless of r
Autor:
Philip P. Hofmeister, Shannon E. Lee, Anala Gossai, Irene Kaganman, Richard Pazdur, Melisa Tucker, Melissa D. Curtis, David E. Light, Jizu Zhi, Sean Khozin, Gideon M. Blumenthal, Marta Bralic, Aracelis Z. Torres, Rebecca A. Miksad, Kenneth R. Carson, Amy P. Abernethy
Publikováno v:
The Oncologist. 24:648-656
Background Evidence from cancer clinical trials has strong internal validity but can be difficult to generalize to real-world patient populations. Here we analyzed real-world outcomes of patients with metastatic non-small cell lung cancer (mNSCLC) tr
Autor:
Calvin A. Kraupner-Taylor, Traude H. Beilharz, Belinda J. Goldie, Michael M. See, Bernhard Dichtl, Amanda L. Peterson, Paul Harrison, Darren J. Creek, Angavai Swaminathan, Melissa Jane Curtis, Rachael Emily Turner, David R. Powell, Ralf B. Schittenhelm
Most eukaryotic mRNAs accommodate alternative sites of poly(A) addition in the 3’ untranslated region in order to regulate mRNA function. Here we present a systematic analysis of 3’ end formation factors, which revealed 3’UTR lengthening in res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d016f28f15ed41108701e1128727071
https://doi.org/10.1101/2020.12.01.407171
https://doi.org/10.1101/2020.12.01.407171
Autor:
Ben Holzman, Melissa D. Curtis, Paul You, Aracelis Z. Torres, Amy P. Abernethy, Sandra D. Griffith, Melisa Tucker, William B. Capra, Gillis Carrigan, Michael Taylor, Brandon Arnieri
Publikováno v:
Health Services Research
Objective To create a high-quality electronic health record (EHR)-derived mortality dataset for retrospective and prospective real-world evidence generation. Data sources/study setting Oncology EHR data, supplemented with external commercial and US S
Autor:
Shannon E. Lee, David E. Light, Anala Gossai, Sean Khozin, Aracelis Z. Torres, Amy P. Abernethy, Rachael Sorg, Jizu Zhi, Payal Patel, Gideon M. Blumenthal, Melissa D. Curtis, Nathan C. Nussbaum, Richard Pazdur, Melisa Tucker
Publikováno v:
The oncologist. 23(3)
Background Evidence from cancer clinical trials can be difficult to generalize to real-world patient populations, but can be complemented by real-world evidence to optimize personalization of care. Further, real-world usage patterns of programmed cel