Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Melissa A Chambers"'
Publikováno v:
Gynecologic Oncology Reports, Vol 48, Iss , Pp 101214- (2023)
Background: Primary vaginal cancer is rare and comprises 1–2% of female genital tract cancers. Among the types of vaginal cancer, adenocarcinoma accounts for only 10% with the peak incidence in women less than 20 years old. Clear cell type vaginal
Externí odkaz:
https://doaj.org/article/08efe5001d2146b4ad82ce2afac0bb54
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 9, Iss 3, p 89 (2022)
Maternal mortality in the United States has been on the rise. Every year, about 700 women die from pregnancy-related complications. Cardiovascular disease (CVD) accounts for a large majority of pregnancy-related deaths driven by the lack of recogniti
Externí odkaz:
https://doaj.org/article/10d22dd02fbd4b9aabff2904f0fe94d7
Publikováno v:
AACE Clinical Case Reports, Vol 4, Iss 3, Pp 209-212 (2018)
ABSTRACT: Objective: 22q11.2 Deletion syndrome (22q11.2DS) is the most common chromosome deletion syndrome and increases the risk of autoimmune conditions, including thyroid disease, cytopenias, and juvenile rheumatoid arthritis. We report two unusua
Externí odkaz:
https://doaj.org/article/ed5a3c3c76ab444eaf269be84b030b24
Autor:
Michele Vigolo, Melissa G. Chambers, Laure Willen, Dehlia Chevalley, Klaus Maskos, Alfred Lammens, Aubry Tardivel, Dolon Das, Christine Kowalczyk-Quintas, Sonia Schuepbach-Mallepell, Cristian R. Smulski, Mahya Eslami, Antonius Rolink, Edith Hummler, Eileen Samy, Yves Fomekong Nanfack, Fabienne Mackay, Maofu Liao, Henry Hess, Xuliang Jiang, Pascal Schneider
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
BAFF is an important cytokine for B cell survival, and is a therapeutic target for autoimmune disorders. Here the authors show that a 'flap' region of BAFF converts BAFFR binding events into survival signals and, with structural data, that this ‘fl
Externí odkaz:
https://doaj.org/article/843bbc0b96a640bc806daedcfd909b7b
Autor:
Kevin A. Cassady, David F. Bauer, Justin Roth, Melissa R. Chambers, Trent Shoeb, Jennifer Coleman, Mark Prichard, G. Yancey Gillespie, James M. Markert
Publikováno v:
Molecular Therapy: Oncolytics, Vol 5, Iss C, Pp 1-10 (2017)
Oncolytic herpes simplex virus (oHSV) type I constructs are investigational anti-neoplastic agents for a variety of malignancies, including malignant glioma. Clinical trials to date have supported the safety of these agents even when directly adminis
Externí odkaz:
https://doaj.org/article/ef22f1f162be48579e6b019ca1e467a2
Autor:
Tobias W Giessen, Benjamin J Orlando, Andrew A Verdegaal, Melissa G Chambers, Jules Gardener, David C Bell, Gabriel Birrane, Maofu Liao, Pamela A Silver
Publikováno v:
eLife, Vol 8 (2019)
Iron storage proteins are essential for cellular iron homeostasis and redox balance. Ferritin proteins are the major storage units for bioavailable forms of iron. Some organisms lack ferritins, and it is not known how they store iron. Encapsulins, a
Externí odkaz:
https://doaj.org/article/b4ec40f71a084d3eb8e1b408a9372b86
Publikováno v:
Endocrine Practice. 28:479-485
Infection with SARS-CoV-2 induces a proinflammatory state that causes hyperglycemia and may precipitate diabetic ketoacidosis (DKA) in patients with known or new-onset diabetes. We examined the trends in new-onset diabetes and DKA prior to and follow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab980b6ca75f897abcbb087ff873cce0
https://doi.org/10.1016/j.eprac.2022.02.005
https://doi.org/10.1016/j.eprac.2022.02.005
Autor:
Mu-Ping Nieh, Holger A. Scheidt, Scott E Collier, Daniel Huster, Melissa G. Chambers, Robert L. McFeeters, George A. Pantelopulos, Kristine F Parson, Haley R. Harrington, Brandon T. Ruotolo, Kathleen F. Mittendorf, John E. Straub, Markus Voehler, Richard A. Stein, Charles R. Sanders, John Katsaras, Shuo Qian, Sarah M Fantin, Kuo-Chih Shih, James M. Hutchison
Publikováno v:
J Am Chem Soc
How the distinctive lipid composition of mammalian plasma membranes impacts membrane protein structure is largely unexplored, partly because of the dearth of isotropic model membrane systems that contain abundant sphingolipids and cholesterol. This g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af23aeea4e0d960366b4c7c1dac8c400
https://doi.org/10.1021/jacs.0c04669
https://doi.org/10.1021/jacs.0c04669
Autor:
Chao Fan, Benjamin J. Orlando, Melissa G. Chambers, Maofu Liao, Minrui Fan, Nathan M. Fastman, Liang Feng, Xiaofang Xu, Yan Xu, Jinru Zhang, Kay Perry
Publikováno v:
Nature. 559:575-579
Mitochondrial calcium uptake plays critical roles in regulating ATP production, intracellular calcium signaling, and cell death. This uptake is mediated by a highly selective calcium channel called the mitochondrial calcium uniporter. Here, we determ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e91e5e42519b97fd4137003670ca485c
https://doi.org/10.1038/s41586-018-0330-9
https://doi.org/10.1038/s41586-018-0330-9
Autor:
Elena J Clark, Madhumita Sinha, William C. Knowler, Melissa A Chambers, Sanil P. Reddy, Diana L Dunnigan, Stephanie K. Tanamas, Robert G. Nelson, Robert L. Hanson
Publikováno v:
Pediatric Diabetes. 19:622-629
OBJECTIVES The risk of early-onset type 2 diabetes associated with the severity of obesity in youth is not well understood. This study aims to determine metabolic alterations and type 2 diabetes risk among American Indian children who are obese or se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4fd8d1dfcde461fd08602fe12f79ae4
https://doi.org/10.1111/pedi.12627
https://doi.org/10.1111/pedi.12627