Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Melissa A Bellinger"'
Autor:
Melissa A Bellinger, James S Bean, Melissa A Rader, Kathleen M Heinz-Taheny, Jairo S Nunes, Joseph V Haas, Laura F Michael, Mark D Rekhter
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e93297 (2014)
BACKGROUND: Acute kidney injury (AKI) is a syndrome characterized by the rapid loss of the kidney excretory function and is strongly associated with increased early and long-term patient morbidity and mortality. Early diagnosis of AKI is challenging;
Externí odkaz:
https://doaj.org/article/ed5393dd682c48c7a0d43188c1bf53c0
Autor:
Nicholas B. Blackburn, Laura F. Michael, Peter J. Meikle, Juan M. Peralta, Marian Mosior, Scott McAhren, Hai H. Bui, Melissa A. Bellinger, Corey Giles, Satish Kumar, Ana C. Leandro, Marcio Almeida, Jacquelyn M. Weir, Michael C. Mahaney, Thomas D. Dyer, Laura Almasy, John L. VandeBerg, Sarah Williams-Blangero, David C. Glahn, Ravindranath Duggirala, Mark Kowala, John Blangero, Joanne E. Curran
Publikováno v:
Journal of Lipid Research, Vol 60, Iss 9, Pp 1630-1639 (2019)
The de novo ceramide synthesis pathway is essential to human biology and health, but genetic influences remain unexplored. The core function of this pathway is the generation of biologically active ceramide from its precursor, dihydroceramide. Dihydr
Externí odkaz:
https://doaj.org/article/7f7fa522a72f41e89dbc1874ed90eccd
Autor:
Melissa A. Bellinger, Juan M. Peralta, Sarah Williams-Blangero, Harald H H Göring, Joanne E. Curran, Kevin Huynh, John L. VandeBerg, Corey Giles, Ana C Leandro, David C. Glahn, Nicholas B. Blackburn, Satish Kumar, Ravindranath Duggirala, Laura F. Michael, Michael C. Mahaney, John Blangero, Peter J. Meikle
Publikováno v:
Circulation: Genomic and Precision Medicine. 14
Background: The identification and understanding of therapeutic targets for atherosclerotic cardiovascular disease is of fundamental importance given its global health and economic burden. Inhibition of ANGPTL3 (angiopoietin-like 3) has demonstrated
Autor:
Ana C Leandro, Jacquelyn M. Weir, Joanne E. Curran, Marian Mosior, Juan M. Peralta, Satish Kumar, Michael C. Mahaney, Melissa A. Bellinger, Laura Almasy, John L. VandeBerg, Peter J. Meikle, David C. Glahn, Sarah Williams-Blangero, Nicholas B. Blackburn, Corey Giles, Ravindranath Duggirala, Marcio Almeida, John Blangero, Laura F. Michael, Mark C. Kowala, Thomas D. Dyer, Scott M. McAhren, Hai H. Bui
Publikováno v:
Journal of Lipid Research, Vol 60, Iss 9, Pp 1630-1639 (2019)
The de novo ceramide synthesis pathway is essential to human biology and health, but genetic influences remain unexplored. The core function of this pathway is the generation of biologically active ceramide from its precursor, dihydroceramide. Dihydr
Autor:
Nicholas B, Blackburn, Peter J, Meikle, Juan M, Peralta, Satish, Kumar, Ana C, Leandro, Melissa A, Bellinger, Corey, Giles, Kevin, Huynh, Michael C, Mahaney, Harald H H, Göring, John L, VandeBerg, Sarah, Williams-Blangero, David C, Glahn, Ravindranath, Duggirala, John, Blangero, Laura F, Michael, Joanne E, Curran
Publikováno v:
Circ Genom Precis Med
BACKGROUND: The identification and understanding of therapeutic targets for atherosclerotic cardiovascular disease (ASCVD) is of fundamental importance given its global health and economic burden. Inhibition of angiopoietin-like 3 (ANGPTL3) has demon
Autor:
Nicholas B, Blackburn, Laura F, Michael, Peter J, Meikle, Juan M, Peralta, Marian, Mosior, Scott, McAhren, Hai H, Bui, Melissa A, Bellinger, Corey, Giles, Satish, Kumar, Ana C, Leandro, Marcio, Almeida, Jacquelyn M, Weir, Michael C, Mahaney, Thomas D, Dyer, Laura, Almasy, John L, VandeBerg, Sarah, Williams-Blangero, David C, Glahn, Ravindranath, Duggirala, Mark, Kowala, John, Blangero, Joanne E, Curran
Publikováno v:
J Lipid Res
The de novo ceramide synthesis pathway is essential to human biology and health, but genetic influences remain unexplored. The core function of this pathway is the generation of biologically active ceramide from its precursor, dihydroceramide. Dihydr
Autor:
Mark David Rekhter, Jairo S. Nunes, Laura F. Michael, James S. Bean, Kathleen M. Heinz-Taheny, Joseph V. Haas, Melissa A. Bellinger, Melissa A. Rader
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 4, p e93297 (2014)
PLoS ONE, Vol 9, Iss 4, p e93297 (2014)
BACKGROUND: Acute kidney injury (AKI) is a syndrome characterized by the rapid loss of the kidney excretory function and is strongly associated with increased early and long-term patient morbidity and mortality. Early diagnosis of AKI is challenging;
Autor:
Jason S. Troutt, Yue-Wei Qian, Robert J. Konrad, Xiliang Wang, Guoqing Cao, Mariam Ehsani, William E. Alborn, John H. Sloan, Karen Leigh Cox, Melissa A. Bellinger, Mark B. Willey
Publikováno v:
Lipids. 45(8)
ATP-binding cassette transporter A-1 (ABCA1) mediates the transfer of cellular cholesterol to lipid-poor apolipoproteins. Liver X receptors (LXRs) are regulators of cholesterol homeostasis that increase transcription of ABCA1. Synthetic LXR agonists