Výsledky vyhledávání - "Melissa A, Fischer"

Akademický článek

Rapid prototyping of perfusion cell culture devices for three-dimensional imaging of mesenchymal stem cell deposition and proliferation

Autor: Taylor E. Scott, Tim Boccarossa, David Florian, Melissa A. Fischer, Sun H. Peck, Michael R. Savona, Georg Pingen, Scott A. Guelcher

Publikováno v: Heliyon, Vol 10, Iss 15, Pp e35103- (2024)

Perfusion of porous scaffolds transports cells to the surface to yield cellular constructs for 3D models of disease and for tissue engineering applications. While ceramic scaffolds mimic the structure and composition of trabecular bone, their opacity

Externí odkaz: https://doaj.org/article/ebb96dae6dcf40f7b7910d0c89bb045e

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Akademický článek

Selective inhibition of MCL1 overcomes venetoclax resistance in a murine model of myelodysplastic syndromes

Autor: Melissa A. Fischer, Yuanbin Song, Maria P. Arrate, Rana Gbyli, Matthew T. Villaume, Brianna N. Smith, Merrida A. Childress, Thomas P. Stricker, Stephanie Halene, Michael R. Savona

Publikováno v: Haematologica, Vol 108, Iss 2 (2022)

Treatment for myelodysplastic syndromes (MDS) remains insufficient due to clonal heterogeneity and lack of effective clinical therapies. Dysregulation of apoptosis is observed across MDS subtypes regardless of mutations and represents an attractive t

Externí odkaz: https://doaj.org/article/59613419e2c2473984ff9a5e86775d97

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Akademický článek

A REDCap-based model for electronic consent (eConsent): Moving toward a more personalized consent

Autor: Colleen E. Lawrence, Leah Dunkel, Mark McEver, Tiffany Israel, Robert Taylor, Germán Chiriboga, Karin Valentine Goins, Elizabeth J. Rahn, Amy S. Mudano, Erik D. Roberson, Carol Chambless, Virginia G. Wadley, Maria I. Danila, Melissa A. Fischer, Yvonne Joosten, Kenneth G. Saag, Jeroan J. Allison, Stephenie C. Lemon, Paul A. Harris

Publikováno v: Journal of Clinical and Translational Science, Vol 4, Pp 345-353 (2020)

AbstractIntroduction:The updated common rule, for human subjects research, requires that consents “begin with a ‘concise and focused’ presentation of the key information that will most likely help someone make a decision about whether to partic

Externí odkaz: https://doaj.org/article/81efbc8306834eee8a2b75e9b13e83b6

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Nanoparticle STING Agonist Reprograms the Bone Marrow to an Antitumor Phenotype and Protects Against Bone Destruction

Autor: David C. Florian, Natalie E. Bennett, Mateusz Odziomek, Jessalyn J. Baljon, Mohamed Wehbe, Alyssa R. Merkel, Melissa A. Fischer, Michael R. Savona, Julie A. Rhoades, Scott A. Guelcher, John T. Wilson

Publikováno v: Cancer Research Communications. 3:223-234

When breast cancer metastasizes to bone, treatment options are limited. Failure to treat bone metastases is thought to be due to therapy-resistant features of the bone marrow microenvironment. Using a murine model of bone metastatic mammary carcinoma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0f206bf8331dc1c295d107475471aa7d
https://doi.org/10.1158/2767-9764.crc-22-0180

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Akademický článek

Simulation-based power and sample size calculation for designing interrupted time series analyses of count outcomes in evaluation of health policy interventions

Autor: Wei Liu, Shangyuan Ye, Bruce A. Barton, Melissa A. Fischer, Colleen Lawrence, Elizabeth J. Rahn, Maria I. Danila, Kenneth G. Saag, Paul A. Harris, Stephenie C. Lemon, Jeroan J. Allison, Bo Zhang

Publikováno v: Contemporary Clinical Trials Communications, Vol 17, Iss , Pp - (2020)

Objective: The purpose of this study was to present the design, model, and data analysis of an interrupted time series (ITS) model applied to evaluate the impact of health policy, systems, or environmental interventions using count outcomes. Simulati

Externí odkaz: https://doaj.org/article/d63de003e238460c8347bc0f3664739e

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Akademický článek

Preparing Medical Students to Be Physician Leaders: A Leadership Training Program for Students Designed and Led by Students

Autor: Kristen Richard, Michael Noujaim, Luanne E. Thorndyke, Melissa A. Fischer

Publikováno v: MedEdPORTAL, Vol 15 (2019)

Introduction Leadership is an area of education and training that is critical to the development of medical providers as health care professionals, yet few medical school curricula offer formal training in this area. Methods We designed and implement

Externí odkaz: https://doaj.org/article/f902d7ee357e467abdcf1669aedcff2e

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Akademický článek

High-Resolution Mapping of RNA Polymerases Identifies Mechanisms of Sensitivity and Resistance to BET Inhibitors in t(8;21) AML

Autor: Yue Zhao, Qi Liu, Pankaj Acharya, Kristy R. Stengel, Quanhu Sheng, Xiaofan Zhou, Hojoong Kwak, Melissa A. Fischer, James E. Bradner, Stephen A. Strickland, Sanjay R. Mohan, Michael R. Savona, Bryan J. Venters, Ming-Ming Zhou, John T. Lis, Scott W. Hiebert

Publikováno v: Cell Reports, Vol 16, Iss 7, Pp 2003-2016 (2016)

Bromodomain and extra-terminal domain (BET) family inhibitors offer an approach to treating hematological malignancies. We used precision nuclear run-on transcription sequencing (PRO-seq) to create high-resolution maps of active RNA polymerases acros

Externí odkaz: https://doaj.org/article/cf9b89b3be554977ab7d018484f46c0c

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Data from Nanoparticle STING Agonist Reprograms the Bone Marrow to an Antitumor Phenotype and Protects Against Bone Destruction

Autor: John T. Wilson, Scott A. Guelcher, Julie A. Rhoades, Michael R. Savona, Melissa A. Fischer, Alyssa R. Merkel, Mohamed Wehbe, Jessalyn J. Baljon, Mateusz Odziomek, Natalie E. Bennett, David C. Florian

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::629d67c1b0a0ef59a15cd822683fc8fa
https://doi.org/10.1158/2767-9764.c.6551166.v1

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