Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Melissa, Prentiss"'
Autor:
Joy G. Ghosh, Andrew A. Nguyen, Chad E. Bigelow, Stephen Poor, Yubin Qiu, Nalini Rangaswamy, Richard Ornberg, Brittany Jackson, Howard Mak, Tucker Ezell, Vania Kenanova, Elisa de la Cruz, Ana Carrion, Bijan Etemad-Gilbertson, Roxana Garcia Caro, Kan Zhu, Vinney George, Jirong Bai, Radhika Sharma-Nahar, Siyuan Shen, Yiqin Wang, Kulandayan K. Subramanian, Elizabeth Fassbender, Michael Maker, Shawn Hanks, Joanna Vrouvlianis, Barrett Leehy, Debby Long, Melissa Prentiss, Viral Kansara, Bruce Jaffee, Thaddeus P. Dryja, Michael Roguska
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Retinal vascular disease treatments involve frequent pharmacological intraocular administrations. Here the authors present a method to increase the half-life of injected drugs by fusing these to a hyaluronan-binding peptide, which might lead to less
Externí odkaz:
https://doaj.org/article/f0adf43d440f4267b734d5d4506d7186
Autor:
Nello Mainolfi, Takeru Ehara, Rajeshri G. Karki, Karen Anderson, Aengus Mac Sweeney, Sha-Mei Liao, Upendra A. Argikar, Keith Jendza, Chun Zhang, James Powers, Daniel W. Klosowski, Maura Crowley, Toshio Kawanami, Jian Ding, Myriam April, Cornelia Forster, Michael Serrano-Wu, Michael Capparelli, Rrezarta Ramqaj, Catherine Solovay, Frederic Cumin, Thomas M. Smith, Luciana Ferrara, Wendy Lee, Debby Long, Melissa Prentiss, Andrea De Erkenez, Louis Yang, Fang Liu, Holger Sellner, Finton Sirockin, Eric Valeur, Paulus Erbel, Daniela Ostermeier, Paul Ramage, Bernd Gerhartz, Anna Schubart, Stefanie Flohr, Nathalie Gradoux, Roland Feifel, Barbara Vogg, Christian Wiesmann, Jürgen Maibaum, Jörg Eder, Richard Sedrani, Richard A. Harrison, Muneto Mogi, Bruce D. Jaffee, Christopher M. Adams
Publikováno v:
Journal of Medicinal Chemistry. 63:5697-5722
Autor:
Joanna Vrouvlianis, Xiaoqiu Wu, Christie L. Bell, Viral Kansara, Q Medley, Henry Y. Wu, Qian Huang, Hui Li, Terri L. McGee, Barrett Leehy, Vanessa Kainz, Melissa Prentiss, YongYao Xu, A.P. da Cunha, Qin Zhang, Chad E Bigelow, Nalini Rangaswamy
Publikováno v:
Current Eye Research. 43:553-565
The concept of tissue-dependent cytokine hierarchy has been demonstrated in a number of diseases, but it has not been investigated in ophthalmic diseases. Here, we evaluated the functional hierarchy of interleukin-1β (IL-1β), IL-6, IL-17A, and tumo
Autor:
Muneto Mogi, Debby Long, Patrick J Rudewicz, Viral Kansara, Kerri J. Grove, Melissa Prentiss, Sean Kim
Publikováno v:
SLAS Discovery. 22:1239-1245
Matrix-assisted laser desorption/ionization imaging mass spectrometry (MALDI IMS) is becoming an important technology to determine the distribution of drugs and their metabolites in the tissue of preclinical species after dosing. Interest in IMS is g
Autor:
Ana Carrion, Debby Long, Andrew Anh Nguyen, Michael Roguska, Elisa de la Cruz, Bruce D Jaffee, Stephen Poor, Kulandayan K. Subramanian, Bijan Etemad-Gilbertson, Vania Kenanova, Shawn Hanks, Roxana Garcia Caro, Nalini Rangaswamy, Kan Zhu, Barrett Leehy, Elizabeth Fassbender, Chad E Bigelow, Howard H. Mak, Joy Ghosh, Jirong Bai, Yubin Qiu, Viral Kansara, Radhika Sharma-Nahar, Siyuan Shen, Michael Maker, Melissa Prentiss, Brittany Jackson, Richard Ornberg, Joanna Vrouvlianis, Vinney George, Yiqin Wang, Tucker Ezell, Thaddeus P. Dryja
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Nature Communications
Nature Communications
Protein drugs that neutralize vascular endothelial growth factor (VEGF), such as aflibercept or ranibizumab, rescue vision in patients with retinal vascular diseases. Nonetheless, optimal visual outcomes require intraocular injections as frequently a
Autor:
Anna Vulpetti, Upendra A. Argikar, Stefanie Flohr, Aengus Mac Sweeney, Melissa Prentiss, Edwige Lorthiois, Karen Anderson, David B. Belanger, Sha-Mei Liao, Nan Ji, Christopher M. Adams, Frederic Cumin, Andrea De Erkenez, Nathalie Gradoux, Muneto Mogi, Donglei Liu, Maura Crowley, Keith Jendza, Debby Long, Nello Mainolfi, Catherine Solovay, Ann Brown, Laura R. La Bonte, Rajeshri Ganesh Karki, Omar Delgado, Powers James J, Bruce D Jaffee, Christine F. Gelin
Publikováno v:
Journal of medicinal chemistry. 62(9)
Complement factor D (FD), a highly specific S1 serine protease, plays a central role in the amplification of the alternative complement pathway (AP) of the innate immune system. Dysregulation of AP activity predisposes individuals to diverse disorder