Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Melissa, Desrosiers"'
Autor:
Hanen Khabou, Elaine Orendorff, Francesco Trapani, Marco Rucli, Melissa Desrosiers, Pierre Yger, Deniz Dalkara, Olivier Marre
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 31, Iss , Pp 101107- (2023)
Most inherited retinal dystrophies display progressive photoreceptor cell degeneration leading to severe visual impairment. Optogenetic reactivation of inner retinal neurons is a promising avenue to restore vision in retinas having lost their photore
Externí odkaz:
https://doaj.org/article/b78a68eae9bd436db9cd81cc7fa020a7
Autor:
Juliette Varin, Nassima Bouzidi, Gregory Gauvain, Corentin Joffrois, Melissa Desrosiers, Camille Robert, Miguel Miranda De Sousa Dias, Marion Neuillé, Christelle Michiels, Marco Nassisi, José-Alain Sahel, Serge Picaud, Isabelle Audo, Deniz Dalkara, Christina Zeitz
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 22, Iss , Pp 15-25 (2021)
Complete congenital stationary night blindness (cCSNB) due to mutations in TRPM1, GRM6, GPR179, NYX, or leucine-rich repeat immunoglobulin-like transmembrane domain 3 (LRIT3) is an incurable inherited retinal disorder characterized by an ON-bipolar c
Externí odkaz:
https://doaj.org/article/1f04f05b98504f5194e6bd3d6cde288d
Autor:
Miguel Miranda de Sousa Dias, José-Alain Sahel, Serge Picaud, Christelle Michiels, Melissa Desrosiers, Isabelle Audo, Marco Nassisi, Camille Robert, Deniz Dalkara, Christina Zeitz, Marion Neuillé, Nassima Bouzidi, Corentin Joffrois, Juliette Varin, Gregory Gauvain
Publikováno v:
Molecular Therapy-Methods and Clinical Development
Molecular Therapy-Methods and Clinical Development, 2021, 22, pp.15-25. ⟨10.1016/j.omtm.2021.05.008⟩
Molecular Therapy-Methods and Clinical Development, Nature Publishing Group, 2021, 22, pp.15-25. ⟨10.1016/j.omtm.2021.05.008⟩
Molecular Therapy: Methods & Clinical Development, Vol 22, Iss, Pp 15-25 (2021)
Molecular Therapy. Methods & Clinical Development
Molecular Therapy-Methods and Clinical Development, 2021, 22, pp.15-25. ⟨10.1016/j.omtm.2021.05.008⟩
Molecular Therapy-Methods and Clinical Development, Nature Publishing Group, 2021, 22, pp.15-25. ⟨10.1016/j.omtm.2021.05.008⟩
Molecular Therapy: Methods & Clinical Development, Vol 22, Iss, Pp 15-25 (2021)
Molecular Therapy. Methods & Clinical Development
Complete congenital stationary night blindness (cCSNB) due to mutations in TRPM1, GRM6, GPR179, NYX, or leucine-rich repeat immunoglobulin-like transmembrane domain 3 (LRIT3) is an incurable inherited retinal disorder characterized by an ON-bipolar c
Autor:
Marine Lacomme, Sarah C. Hales, Thomas W. Brown, Katarina Stevanovic, Christine Jolicoeur, Jenny Cai, Therence Bois, Melissa Desrosiers, Deniz Dalkara, Michel Cayouette
Publikováno v:
Science Advances. 8
Accumulation of the microtubule-associated protein Tau is linked to neuronal cell death in tauopathies, but how intraneuronal Tau levels are regulated in health and disease remains unclear. Here, we show that conditional inactivation of the trafficki
Autor:
Hanen Khabou, Elaine Orendorff, Francesco Trapani, Marco Rucli, Melissa Desrosiers, Pierre Yger, Deniz Dalkara, Olivier Marre
Most inherited retinal dystrophies display progressive photoreceptor cell degeneration leading to severe visual impairment. Optogenetic reactivation of inner retinal neurons is a promising avenue to restore vision in retinas having lost their photore
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc00ff4cbba86750cbb798a0f4505daf
https://doi.org/10.1101/2022.07.28.501925
https://doi.org/10.1101/2022.07.28.501925
Autor:
Lacomme M, Hales Sc, Michel Cayouette, Melissa Desrosiers, Cai J, Jolicoeur C, Deniz Dalkara, Bois T, Stevanovic K
Accumulation of the microtubule-associated protein Tau is linked to neuronal cell death in tauopathies, but how exactly intraneuronal Tau levels are regulated in health and disease remains unclear. Here we identify the trafficking adaptor protein Num
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b6f762b39b7c77a105bd5f75764000c
https://doi.org/10.1101/2021.09.28.462203
https://doi.org/10.1101/2021.09.28.462203
Autor:
A. Rosov, Deniz Dalkara, H. Honig, Ron Ofri, Esther Yamin, Eyal Banin, Edward Averbukh, Maya Ross, Melissa Desrosiers, E. Gootwine, Alexey Obolensky, Raaya Ezra-Elia, H. Dvir
Publikováno v:
Gene therapy. 29(10-11)
Sheep carrying a mutated CNGA3 gene exhibit diminished cone function and provide a naturally occurring large animal model of achromatopsia. Subretinal injection of a vector carrying the CNGA3 transgene resulted in long-term recovery of cone function
Autor:
Aat A. Mulder, Peter M Quinn, Sharon I. de Vries, Melissa Desrosiers, C. Henrique Alves, Carolina R. Jost, Jan Wijnholds, Abraham J. Koster, Jan Klooster, Deniz Dalkara
Publikováno v:
Human Molecular Genetics, 28, 105-123. Oxford University Press
Human Molecular Genetics, 28(1), 105-123
Human Molecular Genetics, 28(1), 105-123
Variations in the human Crumbs homolog-1 (CRB1) gene lead to an array of retinal dystrophies including early onset of retinitis pigmentosa (RP) and Leber congenital amaurosis (LCA) in children. To investigate the physiological roles of CRB1 and CRB2
Autor:
Juliette, Varin, Nassima, Bouzidi, Miguel Miranda De Sousa, Dias, Thomas, Pugliese, Christelle, Michiels, Camille, Robert, Melissa, Desrosiers, José-Alain, Sahel, Isabelle, Audo, Deniz, Dalkara, Christina, Zeitz
Publikováno v:
Investigative Ophthalmology & Visual Science
Purpose Complete congenital stationary night blindness (cCSNB) is an incurable inherited retinal disorder characterized by an ON-bipolar cell (ON-BC) defect. GRM6 mutations are the third most prevalent cause of cCSNB. The Grm6−/− mouse model mimi
Autor:
José-Alain Sahel, Fabrice Arcizet, Philippe Hantraye, Serge Picaud, Gregory Gauvain, Claire-Maëlle Fovet, Jens Duebel, Pierre Pouget, Mina A. Khoei, Deniz Dalkara, Joël Chavas, Melissa Desrosiers, Elena Brazhnikova, Ryad Benosman, Didier Pruneau, Olivier Marre, Antoine Chaffiol, Joanna Demilly, Himanshu Akolkar, Anne Douar, Valérie Forster, Romain Caplette, Céline Jaillard, Stéphane Bertin
Restoring vision using optogenetics is an ideal medical application because the eye offers a direct window to access and stimulate the pathological area: the retina. Optogenetic therapy could be applied to diseases with photoreceptor degeneration suc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8d29dcc167fa17ca377fe8e3ece29fe
https://doi.org/10.1101/2020.05.17.100230
https://doi.org/10.1101/2020.05.17.100230