Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Melissa, Bahr"'
Autor:
Alok K. Singh, Rulin Wang, Kara A. Lombardo, Monali Praharaj, C. Korin Bullen, Peter Um, Manish Gupta, Geetha Srikrishna, Stephanie Davis, Oliver Komm, Peter B. Illei, Alvaro A. Ordonez, Melissa Bahr, Joy Huang, Anuj Gupta, Kevin J. Psoter, Patrick S. Creisher, Maggie Li, Andrew Pekosz, Sabra L. Klein, Sanjay K. Jain, Trinity J. Bivalacqua, Srinivasan Yegnasubramanian, William R. Bishai
Publikováno v:
iScience, Vol 26, Iss 10, Pp 107733- (2023)
Summary: Bacillus Calmette-Guérin (BCG) confers heterologous immune protection against viral infections and has been proposed as vaccine against SARS-CoV-2 (SCV2). Here, we tested intravenous BCG vaccination against COVID-19 using the golden Syrian
Externí odkaz:
https://doaj.org/article/9d718645d1e94cacb1bf9abf39d16432
Autor:
Filipa Mota, Camilo A. Ruiz-Bedoya, Elizabeth W. Tucker, Daniel P. Holt, Patricia De Jesus, Martin A. Lodge, Clara Erice, Xueyi Chen, Melissa Bahr, Kelly Flavahan, John Kim, Mary Katherine Brosnan, Alvaro A. Ordonez, Charles A. Peloquin, Robert F. Dannals, Sanjay K. Jain
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-9 (2022)
Pretomanid has been approved for use in cases of multi-drug resistant pulmonary tuberculosis, yet the penetration of this antibiotic into other target tissues is not well established. Authors provide insight on pretomanid pharmacokinetics in the cent
Externí odkaz:
https://doaj.org/article/f0a782321c4e4e36aa37ab969660b2e2
Autor:
Camilo A. Ruiz-Bedoya, Filipa Mota, Elizabeth W. Tucker, Farina J. Mahmud, Maria I. Reyes-Mantilla, Clara Erice, Melissa Bahr, Kelly Flavahan, Patricia de Jesus, John Kim, Catherine A. Foss, Charles A. Peloquin, Dima A. Hammoud, Alvaro A. Ordonez, Carlos A. Pardo, Sanjay K. Jain
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 6 (2022)
Tuberculous meningitis (TB meningitis) is the most severe form of tuberculosis (TB), requiring 12 months of multidrug treatment for cure, and is associated with high morbidity and mortality. High-dose rifampin (35 mg/kg/d) is safe and improves the ba
Externí odkaz:
https://doaj.org/article/60a8e9fb510a41cda1c8b3797413d48b
Autor:
Santosh Dhakal, Camilo A. Ruiz-Bedoya, Ruifeng Zhou, Patrick S. Creisher, Jason S. Villano, Kirsten Littlefield, Jennie Ruelas Castillo, Paula Marinho, Anne E. Jedlicka, Alvaro A. Ordonez, Melissa Bahr, Natalia Majewska, Michael J. Betenbaugh, Kelly Flavahan, Alice R. L. Mueller, Monika M. Looney, Darla Quijada, Filipa Mota, Sarah E. Beck, Jacqueline Brockhurst, Alicia M. Braxton, Natalie Castell, Mitchel Stover, Franco R. D’Alessio, Kelly A. Metcalf Pate, Petros C. Karakousis, Joseph L. Mankowski, Andrew Pekosz, Sanjay K. Jain, Sabra L. Klein
Publikováno v:
mBio, Vol 12, Iss 4 (2021)
ABSTRACT In the coronavirus disease 2019 (COVID-19) pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), more severe outcomes are reported in males than in females, including hospitalizations and deaths. Animal models
Externí odkaz:
https://doaj.org/article/c26a3303ffd040088f12495ee7b31392
Autor:
Oscar Solis, Andrea R. Beccari, Daniela Iaconis, Carmine Talarico, Camilo A. Ruiz-Bedoya, Jerome C. Nwachukwu, Annamaria Cimini, Vanessa Castelli, Riccardo Bertini, Monica Montopoli, Veronica Cocetta, Stefano Borocci, Ingrid G. Prandi, Kelly Flavahan, Melissa Bahr, Anna Napiorkowski, Giovanni Chillemi, Masato Ooka, Xiaoping Yang, Shiliang Zhang, Menghang Xia, Wei Zheng, Jordi Bonaventura, Martin G. Pomper, Jody E. Hooper, Marisela Morales, Avi Z. Rosenberg, Kendall W. Nettles, Sanjay K. Jain, Marcello Allegretti, Michael Michaelides
Publikováno v:
Science advances. 8(48)
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein binds angiotensin-converting enzyme 2 (ACE2) at the cell surface, which constitutes the primary mechanism driving SARS-CoV-2 infection. Molecular interactions between
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb41ef5dd945de1725d33dc51a9cb5e9
https://pubmed.ncbi.nlm.nih.gov/35665018
https://pubmed.ncbi.nlm.nih.gov/35665018
Autor:
Filipa Mota, Camilo Ruiz-Bedoya, Elizabeth Tucker, Daniel Holt, Patricia De Jesus, Martin Lodge, Clara Erice, Xueyi Chen, Melissa Bahr, Kelly Flavahan, John Kim, Mary Katherine Brosnan, Alvaro Ordonez, Charles Peloquin, Robert Dannals, Sanjay Jain
Pretomanid is a nitroimidazole antimicrobial with potent activity against drug-resistant Mycobacterium tuberculosis and approved in combination with bedaquiline and linezolid (BPaL) for the treatment of multidrug-resistant (MDR) pulmonary tuberculosi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84d233a718f3fd605325be6b4014484b
https://doi.org/10.21203/rs.3.rs-1999411/v1
https://doi.org/10.21203/rs.3.rs-1999411/v1
Autor:
Filipa, Mota, Camilo A, Ruiz-Bedoya, Elizabeth W, Tucker, Daniel P, Holt, Patricia, De Jesus, Martin A, Lodge, Clara, Erice, Xueyi, Chen, Melissa, Bahr, Kelly, Flavahan, John, Kim, Mary Katherine, Brosnan, Alvaro A, Ordonez, Charles A, Peloquin, Robert F, Dannals, Sanjay K, Jain
Publikováno v:
Nature communications. 13(1)
Pretomanid is a nitroimidazole antimicrobial active against drug-resistant Mycobacterium tuberculosis and approved in combination with bedaquiline and linezolid (BPaL) to treat multidrug-resistant (MDR) pulmonary tuberculosis (TB). However, the penet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::678e2ebe32005ff8afbcf7782e9e9ca1
https://pubmed.ncbi.nlm.nih.gov/36581633
https://pubmed.ncbi.nlm.nih.gov/36581633
Autor:
Alok K. Singh, Rulin Wang, Kara A. Lombardo, Monali Praharaj, C. Korin Bullen, Peter Um, Stephanie Davis, Oliver Komm, Peter B. Illei, Alvaro A. Ordonez, Melissa Bahr, Joy Huang, Anuj Gupta, Kevin J. Psoter, Sanjay K. Jain, Trinity J. Bivalacqua, Srinivasan Yegnasubramanian, William R. Bishai
COVID-19 continues to exact a toll on human health despite the availability of several vaccines. Bacillus Calmette Guérin (BCG) has been shown to confer heterologous immune protection against viral infections including COVID-19 and has been proposed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f652ab8dcb973489e2f149a10684b51a
https://doi.org/10.1101/2022.03.15.484018
https://doi.org/10.1101/2022.03.15.484018
Autor:
Alok Kumar Singh, Rulin Wang, Kara Lombardo, Monali Praharaj, Korin Bullen, Peter Um, Stephanie Davis, Oliver Komm, Peter Illei, Alvaro Ordonez, Melissa Bahr, Joy Huang, Anuj Gupta, Kevin Psoter, Patrick Creisher, Maggie Li, Andrew Pekosz, Sabra Klein, Sanjay Jain, Trinity Bivalacqua, Srinivasan Yegnasubramanian, William R. Bishai
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c4674115f8dccf4458e554289ab1bf3
https://doi.org/10.2139/ssrn.4199633
https://doi.org/10.2139/ssrn.4199633
Autor:
Camilo A. Ruiz-Bedoya, Filipa Mota, Elizabeth W. Tucker, Farina J. Mahmud, Maria I. Reyes-Mantilla, Clara Erice, Melissa Bahr, Kelly Flavahan, Patricia de Jesus, John Kim, Catherine A. Foss, Charles A. Peloquin, Dima A. Hammoud, Alvaro A. Ordonez, Carlos A. Pardo, Sanjay K. Jain
Publikováno v:
The Journal of clinical investigation. 132(6)
Tuberculous meningitis (TB meningitis) is the most severe form of tuberculosis (TB), requiring 12 months of multidrug treatment for cure, and is associated with high morbidity and mortality. High-dose rifampin (35 mg/kg/d) is safe and improves the ba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e38dee3d98db0f12429daefb5333532d
https://pubmed.ncbi.nlm.nih.gov/35085105
https://pubmed.ncbi.nlm.nih.gov/35085105