Multi-antigen intranasal vaccine protects against challenge with sarbecoviruses and prevents transmission in hamsters

Autor: Ankita Leekha, Arash Saeedi, K M Samiur Rahman Sefat, Monish Kumar, Melisa Martinez-Paniagua, Adrian Damian, Rohan Kulkarni, Kate Reichel, Ali Rezvan, Shalaleh Masoumi, Xinli Liu, Laurence J. N. Cooper, Manu Sebastian, Courtney M. Sands, Vallabh E. Das, Nimesh B. Patel, Brett Hurst, Navin Varadarajan

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)

Abstract Immunization programs against SARS-CoV-2 with commercial intramuscular vaccines prevent disease but are less efficient in preventing infections. Mucosal vaccines can provide improved protection against transmission, ideally for different var

Externí odkaz: https://doaj.org/article/a940c842f9d44fc59a95b85dd66c762e

Diagnostic accuracy of a non-invasive spot-check hemoglobin meter, Masimo Rad-67® pulse CO-Oximeter®, in detection of anemia in antenatal care settings in Kenya

Autor: Angela Koech, Isaac Mwaniki, Joseph Mutunga, Moses Mukhanya, Emily Mwadime, Marvine Ochieng, Grace Mwashigadi, Hiten D. Mistry, Rachel Craik, Peter von Dadelszen, Marleen Temmerman, Stanley Luchters, Geoffrey Omuse, The PRECISE Network, Patricia Okiro, Onesmus Wanje, Consolata Juma, Charlotte Ndana, Douglas Nyankira, Tindi Otieno, Rose Chebet, Winfred Muithi, Washingtone Owino, Quinter Okello, Michael Ochieng, Margaret Wachira, Kelvin Mbote, Mercy Osele, John Kibwanga, Happy Mdigo, Claire Ngure, Joy Wanja, Claire Kiti, Winnie Nzoka, Grace Anyange, Robin Okello, David Mwadziwe, Ruth Mambo, Sarah Maitha, Juma Gumbo, Jamal Salim, Mary Kalido, Salim Mwakanyenze, Anne Mutua, Asha Tunje, Noveline Khatievi, Nathan Barreh, Belinder Orero, Mwanajuma Khamisi, Eric Mataza, Said Lele, Olivia Kasuu, Susan Sidi, Hassan Kopa, Faith Pola, Umberto D’Alessandro, Anna Roca, Hawanatu Jah, Andrew Prentice, Melisa Martinez-Alvarez, Brahima Diallo, Abdul Sesay, Sambou Suso, Yahaya Idris, Baboucarr Njie, Fatima Touray, Fatoumata Kongira, Modou F.S. Ndure, Gibril Gabbidon, Lawrence Gibba, Abdoulie Bah, Yorro Bah, Esperança Sevene, Anifa Vala, Sonia Maculuve, Corssino Tchavana, Helena Boene, Lazaro Quimice, Salesio Macuacua, Carla Carrilho, Laura A. Magee, Marie-Laure Volvert, Thomas Mendy, Donna Russell, Prestige Tatenda Makanga, Liberty Makacha, Reason Mlambo, Lucilla Poston, Rachel Tribe, Sophie Moore, Tatiana Salisbury, Aris Papageorghiou, Alison Noble, Hannah Blencowe, Veronique Filippi, Joy Lawn, Matt Silver, Joseph Akuze, Ursula Gazeley, Judith Cartwright, Guy Whitley, Sanjeev Krishna, Marianne Vidler, Jing (Larry) Li, Jeff Bone, Mai-Lei (Maggie) Woo Kinshella, Domena Tu, Ash Sandhu, Kelly Pickerill, Carla Carillho, Benjamin Barratt

Publikováno v: Frontiers in Global Women's Health, Vol 5 (2024)

BackgroundPoint of care hemoglobin meters play key roles in increasing access to anemia screening in antenatal care especially in settings with limited access to laboratories. We aimed to determine the diagnostic accuracy of a non-invasive spot-check

Externí odkaz: https://doaj.org/article/06d1b37a6311407c95b04d9f994e23e1

Postpartum recovery after severe maternal morbidity in Kilifi, Kenya: a grounded theory of recovery trajectories beyond 42 days

Autor: Sanjeev Krishna, Jing Li, Andrew Shennan, Prestige Tatenda Makanga, Helena Boene, Marianne Vidler, Laura A Magee, Esperanca Sevene, Peter von Dadelszen, Eusébio Macete, Anifa Vala, Salésio Macuacua, Sónia Maculuve, Jane Sandall, Aris Papageorghiou, Veronique Filippi, Lucilla Poston, Sergio A Silverio, Lucy Chappell, Melisa Martinez-Alvarez, Geoffrey Omuse, Guy Whitley, Hannah Blencowe, Rachel Craik, Carla Carrilho, Marleen Temmerman, Kelly Pickerill, Angela Koech Etyang, Anna Roca, Donna Russell, Umberto D’Alessandro, Hawanatu Jah, Andrew Prentice, Brahima Diallo, Patricia Okiro, Corssino Tchavana, Lazaro Quimice, Inacio Mandomando, Liberty Makacha, Rachel Tribe, Sophie Moore, Tatiana Salisbury, Ben Barratt, Alison Noble, Joy Lawn, Matt Silver, Judith Cartwright, Domena Tu, Marie-Laure Volvert, Laura Magee, Reason Mlambo, Ursula Gazeley, Marvine Caren Ochieng, Onesmus Wanje, Grace Mwashigadi, Nathan Barreh, Alice Mnyazi Kombo, Mwanajuma Bakari, Grace Maitha, Abdul Sesay, Sambou Suso, Baboucarr Njie, Fatima Touray, Yahaya Idris, Fatoumata Kongira, Modou F S Ndure, Lawrence Gibba, Abdoulie Bah, Angela Koech, Consolata Juma, Joseph Mutunga, Isaac Mwaniki, Moses Mukhanya, Marvin Ochieng, Emily Mwadime, Hiten Mistry, Thomas Mendy, Joseph Waiswa, Jeff Bone, Woo Kinshella Mai-Lei, Ash Sandhu, Yorro Bah

Publikováno v: BMJ Global Health, Vol 9, Iss 6 (2024)

Introduction The burden of severe maternal morbidity is highest in sub-Saharan Africa, and its relative contribution to maternal (ill) health may increase as maternal mortality continues to fall. Women’s perspective of their long-term recovery foll

Externí odkaz: https://doaj.org/article/9c9e0f245b6341828ed5ef35f582dbef

Learning from success: the main drivers of the maternal and newborn health transition in seven positive-outlier countries and implications for future policies and programmes

Autor: Neff Walker, James Blanchard, Nadia Akseer, Loveday Penn-Kekana, Kerry Wong, Oona Maeve Renee Campbell, Bouchra Assarag, Vincent de Brouwere, Adam Koon, Isabelle Lange, Kerry Scott, Ties Boerma, Shajy Isac, BM Ramesh, Neil Spicer, Cesar Victora, Shams El Arifeen, Jessica King, Abdoulaye Maïga, Agbessi Amouzou, Robert Black, Shelley Walton, Melisa Martinez-Alvarez, Catherine Pitt, Nasreen Jessani, Hannah Blencowe, Andrea Blanchard, Dessalegn Melesse, Elizabeth Hazel, Nathaniel Gerthe, Neha Singh, Safia Jiwani, Reynold Washington, Himanshu Bhushan, Melinda Munos, Cauane Blumenberg, Gloria Ikilezi, Ritu Agarwal, Aniqa Tasnim Hossain, Ashenif Tadele, Aluisio Barros, William E Oswald, Rachid Bezad, Yvonne Tam, Usha Ram, Prakash Kumar, Mitali Raja, Diksha Dhupar, Ashutosh Kothari, Manoj Alagarajan, Shoummo Sen Gupta, Kisan Algur, Lakshmi Sripada, Thirumalai Narayanan, Lamou Ousseini Youssoufa, Aida Mounkaila, Assanatou Bamogo, Sudha Sharma, Dadhi Adhikari, Shegaw Mulunesh, Ahmed E Rahman, Sanae El Omrani, Mareme Diallo, Aminata Ka, Malick Kante, Yahaya Mahamadou, Moussa Mohamed, Abdoua E Dagobi, Nehmat el Helou, Heather Jue-Wong, Cheikh MBacke, Ryan Fitzgerald, Rowan Hussein, Jordan-Tate Thomas

Publikováno v: BMJ Global Health, Vol 9, Iss Suppl 2 (2024)

Externí odkaz: https://doaj.org/article/a2ab76dcf561433a87a36ef2810b234d

Perceptions and acceptability of the controlled human malaria infection (CHMI) model in The Gambia: a qualitative study

Autor: Edgard Diniba Dabira, Alexandra Fehr, Nathalie Beloum, Jean-Pierre Van geertruyden, Jane Achan, Annette Erhart, Melisa Martinez-Alvarez, Umberto D’Alessandro

Publikováno v: Scientific Reports, Vol 13, Iss 1, Pp 1-8 (2023)

Abstract Controlled human malaria infection (CHMI) studies, i.e. the deliberate infection of healthy volunteers with malaria parasites to study immune response and/or test drug or vaccine efficacy, are increasingly being conducted in malaria endemic

Externí odkaz: https://doaj.org/article/3259602eb96e4f098c46725ea4431370