Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Melis Kant"'
Autor:
Melis Kant, Pawel Jaruga, Erdem Coskun, Samuel Ward, Alexander D. Stark, Thomas Baumann, David Becker, Amitava Adhikary, Michael D. Sevilla, Miral Dizdaroglu
Publikováno v:
ACS Omega, Vol 6, Iss 25, Pp 16600-16611 (2021)
Externí odkaz:
https://doaj.org/article/a4afeb22f0254ec8b928e1dcb7ec7022
Autor:
Ayten Nalbant, Melis Kant
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0164380 (2016)
Aggregatibacter actinomycetemcomitans (Aa) expresses a 64-kDa GroEL protein belonging to the heat shock family of proteins. This protein has been shown to influence human host cells, but the apoptotic capacity of the GroEL protein regarding T cells i
Externí odkaz:
https://doaj.org/article/fa00093fd9eb4c63bd3719cf0bbf9ef8
Autor:
Pawel Jaruga, Rachana Tomar, Melis Kant, Vladimir Vartanian, Benjamin Sexton, Carmelo J. Rizzo, Robert J. Turesky, Michael P. Stone, R. Stephen Lloyd, Miral Dizdaroglu
Publikováno v:
ACS Omega. 8:14841-14854
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec51313dee70b87ce0acfcb2592fb480
https://doi.org/10.1021/acsomega.3c01328
https://doi.org/10.1021/acsomega.3c01328
Publikováno v:
Volume: 7, Issue: 1 516-524
Journal of Basic and Clinical Health Sciences
Journal of Basic and Clinical Health Sciences
Background Cortisol plays a role in the regulation of metabolic homeostasis. Dexamethasone is a powerful synthetic glucocorticoid that acts as an anti-inflammatory and immunosuppressive agent. Plasma free cortisol, which has a low concentration in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51688f6034f321758e9961ce51884745
https://doi.org/10.30621/jbachs.1214727
https://doi.org/10.30621/jbachs.1214727
Autor:
Semir Kose, Melis Kant, Sabahattin Altunyurt, Nazlı Ecem Dal-Bekar, Gamze Tuna, Mehmet Oğuz Erbağcı, Merve Akış, Gul Huray Islekel
Publikováno v:
Reproductive Toxicology. 103:171-180
This study aims to assess the relationship between oxidative DNA damage and iron status in women with gestational diabetes mellitus (GDM) compared to those with normal glucose tolerance in the first and the second trimesters of pregnancy. Maternal se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a0ff612bdfa17c4d5eff9915bcecec0
https://doi.org/10.1016/j.reprotox.2021.05.009
https://doi.org/10.1016/j.reprotox.2021.05.009
Autor:
Samuel Ward, David Becker, Thomas Baumann, Michael D. Sevilla, Pawel Jaruga, Miral Dizdaroglu, Melis Kant, Erdem Coskun, Alexander D. Stark, Amitava Adhikary
Publikováno v:
ACS Omega, Vol 6, Iss 25, Pp 16600-16611 (2021)
ACS Omega
ACS Omega
We report on the physicochemical processes and the products of DNA damage involved in Ne-22 ion-beam radiation of hydrated (12 ± 3 H2O/nucleotide) salmon testes DNA at 77 K. Free radicals trapped at 77 K were identified using electron spin resonance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::deb5a97a9b8e99279a485401db0db96b
https://doi.org/10.1021/acsomega.1c01954
https://doi.org/10.1021/acsomega.1c01954
Autor:
R. Stephen Lloyd, Erdem Coskun, Pawel Jaruga, Eric T. Kool, Melis Kant, Yu Ki Tahara, Miral Dizdaroglu
Publikováno v:
ACS Chem Biol
DNA glycosylases involved in the first step of the DNA base excision repair pathway are promising targets in cancer therapy. There is evidence that reduction of their activities may enhance cell killing in malignant tumors. Recently, two tetrahydroqu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c97fcad837dfeea5236e09f7a57e3ae5
https://doi.org/10.1021/acschembio.0c00877
https://doi.org/10.1021/acschembio.0c00877
Autor:
Melis Kant, Victoria Quintana, Erdem Coskun, Pawel Jaruga, R. Stephen Lloyd, Joann B. Sweasy, Miral Dizdaroglu
Publikováno v:
DNA repair. 117
Base excision repair is the major pathway for the repair of oxidatively-induced DNA damage, with DNA glycosylases removing modified bases in the first step. Human NTHL1 is specific for excision of several pyrimidine- and purine-derived lesions from D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8643eb2e44610a621dfa56f63343c965
https://pubmed.ncbi.nlm.nih.gov/35870279
https://pubmed.ncbi.nlm.nih.gov/35870279
Autor:
kaya N engin, Duygu Harmancı Karagülle, Ceren Durmaz Engin, Melis Kant, Aylin Yaman, Merve Akış, Sevda Özel Yıldız, Hüray İşlekel, Gül Güner Akdoğan, Meltem Söylev Bajin
Purpose: Oxidative stress is known to be a decisive factor in the wide etiopathogenesis of optic neuropathy. This study aimed to comprehensively evaluate the interaction of optic neuropathy’s clinical course with systemic oxidative damage and antio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1efeb4a7f900d4553648d8e09b421c9d
https://avesis.deu.edu.tr/publication/details/8a986b4f-6dcd-4c7b-a948-182308a5ff85/oai
https://avesis.deu.edu.tr/publication/details/8a986b4f-6dcd-4c7b-a948-182308a5ff85/oai
Autor:
Tania Rahim, R. Stephen Lloyd, Joann B. Sweasy, Melis Kant, Alireza G. Senejani, Madison Levinson, Stephen E. Maher, Miral Dizdaroglu, Caroline J. Zeiss, Rithy Meas, Marina Cardó-Vila, Sesha L. A. Paluri, Kaylyn Clairmont, Michael Kashgarian, Isabel Alvarado-Cruz, Pawel Jaruga, Alfred L. M. Bothwell, Erdem Coskun, Matthew J. Burak
Publikováno v:
DNA Repair (Amst)
The Polb gene encodes DNA polymerase beta (Pol β), a DNA polymerase that functions in base excision repair (BER) and microhomology-mediated end-joining. The Pol β-Y265C protein exhibits low catalytic activity and fidelity, and is also deficient in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4ed4da1a3471381db99c441029e0b4f
https://pubmed.ncbi.nlm.nih.gov/34186496
https://pubmed.ncbi.nlm.nih.gov/34186496