Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Melis Debreli Coskun"'
Autor:
Melis Debreli Coskun, Thangirala Sudha, Dhruba J. Bharali, Serap Celikler, Paul J. Davis, Shaker A. Mousa
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Pancreatic cancer decreases survival time and quality of life because of drug resistance and peripheral neuropathy during conventional treatment. This study was undertaken to investigate whether αvβ3 integrin receptor antagonist compounds NDAT and
Externí odkaz:
https://doaj.org/article/70ab0571f80242fe9741bd0c7903edbd
Autor:
Jing Liu, Sarah Lane, Rahul Lall, Michele Russo, Laurie Farrell, Melis Debreli Coskun, Casie Curtin, Raquel Araujo-Gutierrez, Marielle Scherrer-Crosbie, Barry H. Trachtenberg, Jonghan Kim, Emanuela Tolosano, Alessandra Ghigo, Robert E. Gerszten, Aarti Asnani
Publikováno v:
Science Advances. 8
Anthracyclines such as doxorubicin (Dox) are effective chemotherapies, but their use is limited by cardiac toxicity. We hypothesized that plasma proteomics in women with breast cancer could identify new mechanisms of anthracycline cardiac toxicity. W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac764fcc6d706655d88283bda5c62f01
https://doi.org/10.1126/sciadv.adc9245
https://doi.org/10.1126/sciadv.adc9245
Autor:
Noureldien H. E. Darwish, Shaker A. Mousa, Paul J. Davis, Thangirala Sudha, Jahangir A. Satti, Melis Debreli Coskun, Mahboob ur Rehman
Publikováno v:
Radiation research. 196(4)
Tetraiodothyroacetic acid is a ligand of thyrointegrin αvβ3, a protein that is highly expressed in various solid tumors and surrounding neovascular regions. Its nano derivative, Nano-diamino-tetrac (NDAT), has anticancer properties in preclinical m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1cb3415a0801618b903a9f8439dd846
https://pubmed.ncbi.nlm.nih.gov/34260732
https://pubmed.ncbi.nlm.nih.gov/34260732
Autor:
Noureldien H. E. Darwish, Dhruba J. Bharali, Kelly A. Keating, Paul J. Davis, Melis Debreli Coskun, Thangirala Sudha, Shaker A. Mousa, Murat Yalcin, Hung Yun Lin
Publikováno v:
Nanomedicine. 12:195-205
Aim: Nano-diamino-tetrac (NDAT) targets a receptor on integrin alpha v beta 3; alpha v beta 3 is generously expressed by cancer cells and dividing endothelial cells and to a small extent by nonmalignant cells. The tetrac (tetraiodothyroacetic acid) o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fef62ec7e85bd083bfd4dfd48da1c0d
https://doi.org/10.2217/nnm-2016-0315
https://doi.org/10.2217/nnm-2016-0315
Autor:
Noureldien H. E. Darwish, Dhruba J. Bharali, Shaker A. Mousa, Thangirala Sudha, Kelly A. Keating, Paul J. Davis, Hung Yun Lin, Melis Debreli Coskun, Murat Yalcin
Publikováno v:
International Journal of Nanomedicine
Thangirala Sudha,1 Dhruba J Bharali,1 Murat Yalcin,1,2 Noureldien HE Darwish,1,3 Melis Debreli Coskun,1,4 Kelly A Keating,1 Hung-Yun Lin,5,6 Paul J Davis,1,7 Shaker A Mousa1 1The Pharmaceutical Research Institute, Albany College of Pharmacy and Healt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3301127ce94236dab90a59373588795
http://hdl.handle.net/11452/30051
http://hdl.handle.net/11452/30051
Autor:
Shaker A. Mousa, Noureldien H. E. Darwish, Qishan Lin, Paul J. Davis, Dhruba J. Bharali, Melis Debreli-Coskun, Thangirala Sudha
Publikováno v:
Cancer Research. 76:2166-2166
Covalently bound to a poly (lactic-co-glycolic acid) (PLGA) polymer via a linker, tetraiodothyroacetic acid (tetrac) as Nano-diamino-tetrac (NDAT) targets a specific cell surface receptor on the extracellular domain of integrin αvβ3. The integrin i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::865417cc7b6f05ec68d91ff3cc162107
https://doi.org/10.1158/1538-7445.am2016-2166
https://doi.org/10.1158/1538-7445.am2016-2166