Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Melis, Olcum"'
Autor:
Burak I. Arioz, Bora Tastan, Emre Tarakcioglu, Kemal Ugur Tufekci, Melis Olcum, Nevin Ersoy, Alper Bagriyanik, Kursad Genc, Sermin Genc
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Inflammation is a crucial component of various stress-induced responses that contributes to the pathogenesis of major depressive disorder (MDD). Depressive-like behavior (DLB) is characterized by decreased mobility and depressive behavior that occurs
Externí odkaz:
https://doaj.org/article/24e7f872c8254d2b95f741e379e21522
Publikováno v:
Antioxidants, Vol 10, Iss 7, p 1020 (2021)
NLRP3 inflammasome is a part of the innate immune system and responsible for the rapid identification and eradication of pathogenic microbes, metabolic stress products, reactive oxygen species, and other exogenous agents. NLRP3 inflammasome is overac
Externí odkaz:
https://doaj.org/article/86f851ae8b39416a88bb213b3a64ee3a
Autor:
Melis Olcum, Kemal Ugur Tufekci, Devrim Yagmur Durur, Bora Tastan, Irem Nur Gokbayrak, Kursad Genc, Sermin Genc
Publikováno v:
Antioxidants, Vol 10, Iss 5, p 745 (2021)
Ethyl pyruvate is a molecule with anti-inflammatory and pro-metabolic effects. Ethyl pyruvate has been shown to ameliorate the clinical and pathological findings of neurodegenerative diseases such as Alzheimer’s and Parkinson’s Diseases in rodent
Externí odkaz:
https://doaj.org/article/5d1033071eca4fea9df271ade90b7895
Autor:
Melis Olcum, Siyang Fan, Leila Rouhi, Sirisha Cheedipudi, Benjamin Cathcart, Hyun-Hwan Jeong, Zhongming Zhao, Priyatansh Gurha, Ali J. Marian
AimMutations in theDSPgene encoding desmoplakin, a constituent of the desmosomes at the intercalated discs (IDs), cause a phenotype that spans arrhythmogenic cardiomyopathy (ACM) and dilated cardiomyopathy (DCM). It is typically characterized by bive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::18e9437505db14928577b72de5b7cc23
https://doi.org/10.1101/2023.03.02.530831
https://doi.org/10.1101/2023.03.02.530831
Publikováno v:
Molecular Immunology. 140:175-185
SFN, a dietary phytochemical, is a significant member of isothiocyanates present in cruciferous vegetables at high levels in broccoli. It is a well-known activator of the Nrf2/ARE antioxidant pathway. Long since, the therapeutic effects of SFN have b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cd294d7b2caeca786db9602cabd84fb
https://doi.org/10.1016/j.molimm.2021.10.014
https://doi.org/10.1016/j.molimm.2021.10.014
Autor:
Leila, Rouhi, Gaelle, Auguste, Qiong, Zhou, Raffaella, Lombardi, Melis, Olcum, Kimia, Pourebrahim, Sirisha M, Cheedipudi, Saman, Asghar, Kui, Hong, Matthew J, Robertson, Cristian, Coarfa, Priyatansh, Gurha, Ali J, Marian
Publikováno v:
The journal of cardiovascular aging. 2(3)
Mutations in theThe purpose of the study was to determine the contribution of the fibroblasts to DCM caused by LMNA deficiency.TheDeletion of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e4c7bdba7f5de22f50df0c917b3cb19c
https://pubmed.ncbi.nlm.nih.gov/35891706
https://pubmed.ncbi.nlm.nih.gov/35891706
Autor:
Leila Rouhi, Siyang Fan, Sirisha M. Cheedipudi, Melis Olcum, Hyun-Hwan Jeong, Zhongming Zhao, Priyatansh Gurha, Ali J. Marian
Publikováno v:
The journal of cardiovascular aging
The Cre-LoxP technology, including the tamoxifen (TAM) inducible MerCreMer (MCM), is increasingly used to delineate gene function, understand the disease mechanisms, and test therapeutic interventions. We set to determine the effects of TAM-MCM on ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68d37e60fe8adb42e6aaf8045cebd11f
https://doi.org/10.20517/jca.2021.30
https://doi.org/10.20517/jca.2021.30
Autor:
Devrim Yagmur Durur, Bora Tastan, Kemal Ugur Tufekci, Melis Olcum, Hamdiye Uzuner, Gökhan Karakülah, Gorsev Yener, Sermin Genc
Publikováno v:
Journal of molecular neuroscience : MN. 72(6)
Alzheimer's disease (AD) is one of the most severe neurodegenerative diseases observed in the elderly population. Although the hallmarks of AD have been identified, the methods for its definitive diagnosis and treatment are still lacking. Extracellul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42ea93c1342ae5d9de3ba54f38d60e70
https://pubmed.ncbi.nlm.nih.gov/35488079
https://pubmed.ncbi.nlm.nih.gov/35488079
Publikováno v:
Methods in Molecular Biology ISBN: 9781071611692
Since their first discovery more than 20 years ago, miRNAs have been subject to deliberate research and analysis for revealing their physiological or pathological involvement. Regulatory roles of miRNAs in signal transduction, gene expression, and ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf2a7c9a95e3192381c5641e9117ba39
https://doi.org/10.1007/978-1-0716-1170-8_13
https://doi.org/10.1007/978-1-0716-1170-8_13
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2257
Since their first discovery more than 20 years ago, miRNAs have been subject to deliberate research and analysis for revealing their physiological or pathological involvement. Regulatory roles of miRNAs in signal transduction, gene expression, and ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::54434d64373dfe7b170ea718ecacf911
https://pubmed.ncbi.nlm.nih.gov/34432283
https://pubmed.ncbi.nlm.nih.gov/34432283