Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Melinda S. Gordon"'
Autor:
Stavroula Baritaki, Shen Pang, Benjamin Bonavida, Dror Shalitin, Jeffrey A. Steinberg, Richard A. Campbell, Jonathan W. Said, Cathy Wang, Eric Sanchez, Melinda S. Gordon, James R. Berenson, Haiming Chen
Publikováno v:
British Journal of Haematology. 138:467-478
Arsenic trioxide (ATO) induces apoptosis of malignant plasma cells through multiple mechanisms, including inhibition of DNA binding by nuclear factor kappa-B, a key player in the development of chemoresistance in multiple myeloma (MM). This activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bf866a9134cc87d8d98dde6a9b7fb47
https://doi.org/10.1111/j.1365-2141.2007.06675.x
https://doi.org/10.1111/j.1365-2141.2007.06675.x
Autor:
Howard S. Yeh, Hee Jin Lee, Jonathan Ma, Richard A. Campbell, Haiming Chen, James R. Berenson, Gabriel N. Waterman, Cathy Wang, Melinda S. Gordon, Regina A. Swift, Mingjie Li, Steven J. Manyak, Benjamin Bonavida
Publikováno v:
British Journal of Haematology. 133:526-529
Summary Pleiotrophin (PTN), a tightly regulated angiogenic and mitogenic heparin-binding protein, is markedly elevated in a variety of aggressive solid tumours. The role of PTN in haematological malignancies, however, has not been previously evaluate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d60a84328af16938dc22fdcc1e534a5c
https://doi.org/10.1111/j.1365-2141.2006.06052.x
https://doi.org/10.1111/j.1365-2141.2006.06052.x
Publikováno v:
Proceedings of the National Academy of Sciences. 100:4126-4131
Somatic hypermutation (SHM), coupled to selection by antigen, generates high-affinity antibodies during germinal center (GC) B cell maturation. SHM is known to affectBcl6, four additional oncogenes in diffuse large B cell lymphoma, and theCD95/Fasgen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bca5ee7929862d8f8963ba76f090aa3c
https://doi.org/10.1073/pnas.0735266100
https://doi.org/10.1073/pnas.0735266100
Autor:
Michael J. Gilly, William A. May, Cindy S. Malone, Sidne A. Omori, William J. Wood, Christopher T. Denny, Erina K. Miyoshi, Jeff Gimble, Randolph Wall, Alexis A. Thompson, Melinda S. Gordon
Publikováno v:
Genomics. 32:352-357
The pp52 gene encodes an intracellular, F-actin-binding phosphoprotein (also designated LSP1 and WP34) postulated to function in cytoskeleton dynamics and cell motility. We previously reported that different mRNA isoforms are expressed from this gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d8133f6ef26c3a5523e5aeefadb2eef
https://doi.org/10.1006/geno.1996.0129
https://doi.org/10.1006/geno.1996.0129
Autor:
Steven J. Manyak, Thomas F. Deuel, Benjamin Bonavida, Melinda S. Gordon, Dorina Gui, Haiming Chen, Yunchao Chang, Stavroula Baritaki, Richard A. Campbell, Hee Jin Lee, Dror Shalitin, Eric Sanchez, James R. Berenson, Cathy S. Wang, Jonathan W. Said, Mingjie Li
Publikováno v:
Blood. 110(1)
Pleiotrophin (PTN) is an important developmental cytokine that is highly expressed during embryogenesis but shows very limited expression in adult tissues, where it is largely restricted to the brain. High PTN serum levels are associated with a varie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a09b29323a6f397d6b9327f6dd7b794
https://pubmed.ncbi.nlm.nih.gov/17369488
https://pubmed.ncbi.nlm.nih.gov/17369488
Autor:
Jonathan W. Said, Steven J. Manyak, Melinda S. Gordon, Haiming Chen, Cathy Wang, James R. Berenson, Shen Pang, Honghao H. Yang, Nelida N. Sjak-Shie, Dorina Gui, Benjamin Bonavida, Laura M. Popoviciu, Richard A. Campbell
Publikováno v:
International Journal of Oncology.
We set out to generate new human myeloma tumors that grow in immunodeficient mice and can be used for pathophysiological studies and rapid evaluation of new therapies. Fresh whole core bone marrow (BM) biopsies taken from 33 myeloma patients were eng
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d9d9c6908245b97fcfa17073bdc91c2
https://doi.org/10.3892/ijo.28.6.1409
https://doi.org/10.3892/ijo.28.6.1409
Autor:
Michael A. Teitell, Cindy S. Malone, Roman K. Thomas, Melinda S. Gordon, Volker Diehl, Randolph Wall, Jeanette R. Doerr, Paul G. Murray, Qian Tao, Shahe V. Soghomonian, Francesca Fike
Publikováno v:
Journal of molecular biology. 350(4)
Hodgkin and Reed-Sternberg (HRS) cells of classical Hodgkin lymphoma (cHL) and primary effusion lymphoma (PEL) are derived from germinal center (GC) and post-GC B cells, respectively. Neither express many of the B cell genes or surface markers typica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98501303c780426ef23a14c541bbd9fe
https://pubmed.ncbi.nlm.nih.gov/15967459
https://pubmed.ncbi.nlm.nih.gov/15967459
Autor:
Roberta M. Kato, Frederick Lansigan, Alexis A. Thompson, Melinda S. Gordon, Randolph Wall, David J. Rawlings
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 97(10)
Chronic lymphocytic leukemia (CLL) B cells characteristically exhibit low or undetectable surface B cell receptor (BCR) and diminished responses to BCR-mediated signaling. These features suggest that CLL cells may have sustained mutations affecting o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2865d8a38661ef98259263ae45d690b0
https://pubmed.ncbi.nlm.nih.gov/10792036
https://pubmed.ncbi.nlm.nih.gov/10792036
Autor:
Melinda S. Gordon, Benjamin Bonavida, Haiming Chen, Xiaozhong Qian, Richard A. Campbell, Henri Lichenstein, Michael Jeffers, Olivia Trac, Dror Shalitin, Jonathan W. Said, Eric Sanchez, James R. Berenson, Lauren Turker, Shen Pang, Mingjie Li
Publikováno v:
Blood. 108:3483-3483
Histone deacetylase (HDAC) inhibitors represent a new mechanistic class of anti-cancer therapeutics that inhibit HDAC enzymes and have been shown to have anti-proliferative effects in cancer cells (including drug resistance subtypes), induce apoptosi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cac091d2b3cbbc8e9e4d7900e7cd337c
https://doi.org/10.1182/blood.v108.11.3483.3483
https://doi.org/10.1182/blood.v108.11.3483.3483
Autor:
Haiming Chen, Dror Shalitin, Shen Pang, Benjamin Bonavida, Eric Sanchez, James R. Berenson, Lauren Turker, Mingjie Li, Germaine Fuh, Melinda S. Gordon, Jonathan W. Said, Richard A. Campbell, Olivia Trac, Gregory D. Plowman
Publikováno v:
Blood. 108:846-846
Vascular endothelial growth factor (VEGF) is an important signaling protein that plays a critical role in vasculogenesis and angiogenesis, and serves as one of the contributors to physiological or pathological conditions that can stimulate the format
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::172464f0fd4b01be30d336e9c838c799
https://doi.org/10.1182/blood.v108.11.846.846
https://doi.org/10.1182/blood.v108.11.846.846