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pro vyhledávání: '"Melinda R. DeSantis"'
Autor:
Sawako Yoshina, Xiaohua Shen, Randal J. Kaufman, Kenjiro Sakaki, Melinda R. DeSantis, Shohei Mitani, Mon Xiong, Jaeseok Han
Publikováno v:
Proceedings of the National Academy of Sciences. 109:8079-8084
The unfolded protein response (UPR) is an intracellular stress-signaling pathway that counteracts the accumulation of misfolded proteins in the endoplasmic reticulum (ER). Because defects in ER protein folding are associated with many pathological st