Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Melinda K. Hexum"'
Autor:
Zhenya Ni, David A. Knorr, Laurence J.N. Cooper, David Hermanson, Dean A. Lee, Melinda K. Hexum, Dan S. Kaufman, Laura Bendzick
Publikováno v:
Stem Cells Translational Medicine. 2:274-283
Adoptive transfer of antitumor lymphocytes has gained intense interest in the field of cancer therapeutics over the past two decades. Human natural killer (NK) cells are a promising source of lymphocytes for anticancer immunotherapy. NK cells are par
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::655bd00ec854b8e87e9741c4c28ad333
https://doi.org/10.5966/sctm.2012-0084
https://doi.org/10.5966/sctm.2012-0084
Autor:
Daniel A. Vallera, Seung Uk Oh, John R. Ohlfest, Zintis Inde, Dan S. Kaufman, Nate N. Waldron, Melinda K. Hexum
Publikováno v:
Molecular Cancer Therapeutics. 10:1829-1838
A novel anticancer agent was constructed by fusing a gene encoding the scFV that targets both glycosylated and unglycosylated forms of CD133 to a gene fragment encoding deimmunized PE38KDEL. The resulting fusion protein, dCD133KDEL, was studied to de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2a84b657fb66f8d995798c55584c798
https://doi.org/10.1158/1535-7163.mct-11-0206
https://doi.org/10.1158/1535-7163.mct-11-0206
Autor:
David A. Knorr, Dan S. Kaufman, In-Hyun Park, Melinda K. Hexum, Zhenya Ni, Peter J. Southern, Christine L. Clouser, Louis M. Mansky
Publikováno v:
Journal of Virology. 85:43-50
Cell-based therapies against HIV/AIDS have been gaining increased interest. Natural killer (NK) cells are a key component of the innate immune system with the ability to kill diverse tumor cells and virus-infected cells. While NK cells have been show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb21f7f70fdce1fb2b78d8f2b09cd907
https://doi.org/10.1128/jvi.01774-10
https://doi.org/10.1128/jvi.01774-10
Autor:
Russell J. Taylor, Melinda K. Hexum, Dan S. Kaufman, Vesselin R. Penchev, Xinghui Tian, Leonard D. Shultz
Publikováno v:
Stem Cells. 27:2675-2685
Human embryonic stem cells (hESCs) provide an important resource for novel regenerative medicine therapies and have been used to derive diverse cell populations, including hematopoietic and endothelial cells. However, it remains a challenge to achiev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be4fa1f26ce9f9ce671b718ecc86251b
https://doi.org/10.1002/stem.204
https://doi.org/10.1002/stem.204
Autor:
Mike Lepley, Patrick I. Ferrell, Melinda K. Hexum, Ross A. Kopher, Dan S. Kaufman, Amanda Gussiaas
Publikováno v:
Stem cells and development, vol 23, iss 12
To evaluate hematopoietic niche cell populations isolated from human embryonic stem cells (hESCs), we tested the ability of hESC-derived stromal lines to support CD34(+) umbilical cord blood (UCB)- and hESC-derived CD34(+)45(+) cells in long-term cul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6afbc3450f8a150d087feaf966fed73
https://europepmc.org/articles/PMC4046207/
https://europepmc.org/articles/PMC4046207/
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 767
Efficient derivation and isolation of hematopoietic stem cells (HSCs) from human pluripotent stem cell (hPSC) populations remains a major goal in the field of developmental hematopoiesis. These enticing pluripotent stem cells (comprising both human e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3684821bd2abedba12090fdf5504856a
https://pubmed.ncbi.nlm.nih.gov/21822894
https://pubmed.ncbi.nlm.nih.gov/21822894
Publikováno v:
Methods in Molecular Biology ISBN: 9781617792007
Efficient derivation and isolation of hematopoietic stem cells (HSCs) from human pluripotent stem cell (hPSC) populations remains a major goal in the field of developmental hematopoiesis. These enticing pluripotent stem cells (comprising both human e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7b89837090993f472735abbe12402ba
https://doi.org/10.1007/978-1-61779-201-4_32
https://doi.org/10.1007/978-1-61779-201-4_32
Autor:
Patrick I. Ferrell, Melinda K. Hexum, Amanda Gussiaas, Ross A. Kopher, Mike Lepley, Dan S. Kaufman
Publikováno v:
Blood. 118:4804-4804
Abstract 4804 Quantification of putative hematopoietic stem cells (HSCs) in human bone marrow or cord blood is typically assessed by its potential to mediate long-term, multilineage engraftment when transplanted into immunodeficient murine recipients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d56e059eb7b18d8bd3cc0142618c3af
https://doi.org/10.1182/blood.v118.21.4804.4804
https://doi.org/10.1182/blood.v118.21.4804.4804
Autor:
Dan S. Kaufman, Zhenya Ni, Melinda K. Hexum, David A. Knorr, Patrick J. Walsh, Amanda Gussiaas, Minh K Hong
Publikováno v:
Blood. 116:107-107
Abstract 107 Human natural killer (NK) cells are an attractive source of lymphocytes for adoptive immunotherapy. Although our understanding of natural killer cell biology continually grows, translating these concepts to the clinic has fallen behind.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d817ba58030ee707098ecd84f0a3525
https://doi.org/10.1182/blood.v116.21.107.107
https://doi.org/10.1182/blood.v116.21.107.107
Publikováno v:
Blood. 114:2517-2517
Abstract 2517 Poster Board II-494 Osteoclasts are bone resorbing cells located in the bone marrow that play a key role in hematopoiesis and formation of the hematopoietic niche. Previous studies demonstrate osteoclasts arise from the monocyte-macroph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88f843f405869f34655b00cf6f561083
https://doi.org/10.1182/blood.v114.22.2517.2517
https://doi.org/10.1182/blood.v114.22.2517.2517