Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Melinda J. Fasnacht"'
Selenium supplementation suppresses immunological and serological features of lupus in B6.Sle1b mice
Publikováno v:
Autoimmunity, Vol 52, Iss 2, Pp 57-68 (2019)
Systemic lupus erythematosus (SLE) is a debilitating multi-factorial immunological disorder characterized by increased inflammation and development of anti-nuclear autoantibodies. Selenium (Se) is an essential trace element with beneficial anti-cance
Externí odkaz:
https://doaj.org/article/754cca12b3b0417289742e6b20eacc2c
Autor:
Phillip P. Domeier, Sathi Babu Chodisetti, Stephanie L. Schell, Yuka Imamura Kawasawa, Melinda J. Fasnacht, Chetna Soni, Ziaur S.M. Rahman
Publikováno v:
Cell Reports, Vol 24, Iss 2, Pp 406-418 (2018)
Summary: Type 1 interferon (T1IFN) signaling promotes inflammation and lupus pathology, but its role in autoreactive B cell development in the antibody-forming cell (AFC) and germinal center (GC) pathways is unclear. Using a lupus model that allows f
Externí odkaz:
https://doaj.org/article/7b9796ea1cb348bc9d2f93a94e94cf06
Autor:
Phillip P. Domeier, Kristen N. Bricker, Steven F. Ziegler, Nicholas M Choi, Adam J. Fike, Sara A. Luckenbill, Zia Ur Rahman, Stephanie L. Schell, Sathi Babu Chodisetti, Melinda J. Fasnacht
Publikováno v:
J Immunol
MicroRNAs (miRNAs) are involved in healthy B cell responses and the loss of tolerance in systemic lupus erythematosus (SLE), although the role of many miRNAs remains poorly understood. Dampening miR-21 activity was previously shown to reduce splenome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6b4a29c87d45fc56fcb71b39512bdf6
https://doi.org/10.4049/jimmunol.2001039
https://doi.org/10.4049/jimmunol.2001039
Selenium supplementation suppresses immunological and serological features of lupus in B6.Sle1b mice
Publikováno v:
Autoimmunity
Systemic lupus erythematosus (SLE) is a debilitating multi-factorial immunological disorder characterized by increased inflammation and development of anti-nuclear autoantibodies. Selenium (Se) is an essential trace element with beneficial anti-cance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7489f5fba5095a9510102ed7be472aad
https://doi.org/10.1080/08916934.2019.1603297
https://doi.org/10.1080/08916934.2019.1603297
Autor:
Chetna Soni, Zia Ur Rahman, Melinda J. Fasnacht, Phillip P. Domeier, Yuka Imamura Kawasawa, Stephanie L. Schell, Sathi Babu Chodisetti
Publikováno v:
Cell Reports, Vol 24, Iss 2, Pp 406-418 (2018)
Cell reports
Cell reports
SUMMARY Type 1 interferon (T1IFN) signaling promotes inflammation and lupus pathology, but its role in autoreactive B cell development in the antibody-forming cell (AFC) and germinal center (GC) pathways is unclear. Using a lupus model that allows fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7f4dca7e42d6d2283b0589ffb3ba490
http://www.sciencedirect.com/science/article/pii/S2211124718309562
http://www.sciencedirect.com/science/article/pii/S2211124718309562
Publikováno v:
Immunology and Cell Biology. 96:298-315
Mer Tyrosine Kinase receptor (Mer) is involved in anti-inflammatory efferocytosis. Here we report elevated spontaneous germinal center (Spt-GC) responses in Mer-deficient mice (Mer-/- ) that are associated with the loss of SIGN-R1+ marginal zone macr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a71cc677aac3c1f576a8efaa5a52253
https://doi.org/10.1111/imcb.12003
https://doi.org/10.1111/imcb.12003
Autor:
Chetna, Soni, Stephanie L, Schell, Melinda J, Fasnacht, Sathi Babu, Chodisetti, Ziaur Sm, Rahman
Publikováno v:
Immunology and cell biology. 96(3)
Mer Tyrosine Kinase receptor (Mer) is involved in anti-inflammatory efferocytosis. Here we report elevated spontaneous germinal center (Spt-GC) responses in Mer-deficient mice (Mer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::992e77ff76be9966bf9088513fe44f64
https://pubmed.ncbi.nlm.nih.gov/29345385
https://pubmed.ncbi.nlm.nih.gov/29345385
Autor:
Zia Ur Rahman, Chetna Soni, Phillip P. Domeier, Stephanie L. Schell, Melinda J. Fasnacht, Timothy K. Cooper
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 199(12)
Mer tyrosine kinase (Mer) signaling maintains immune tolerance by clearing apoptotic cells (ACs) and inducing immunoregulatory signals. We previously showed that Mer-deficient mice (Mer−/−) have increased germinal center (GC) responses, T cell ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7693cb549529c8d7c22777a08287c4c
https://pubmed.ncbi.nlm.nih.gov/29118245
https://pubmed.ncbi.nlm.nih.gov/29118245
Autor:
Sathi Babu Chodisetti, Phillip P. Domeier, Chetna Soni, Stephanie L. Schell, Melinda J. Fasnacht, Ziaur S.M. Rahman
Publikováno v:
The Journal of Immunology. 198:217.1-217.1
Toll like receptor 7 (TLR7) plays a critical role in systemic autoimmunity. The mechanisms that fine-tune germinal center versus regulatory B cell response in TLR7 mediated autoimmunity remain unclear. Regulatory B cells that produce IL-10 (B10 cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::91bc73d08f48d84826ec6433fd984f91
https://doi.org/10.4049/jimmunol.198.supp.217.1
https://doi.org/10.4049/jimmunol.198.supp.217.1
Autor:
Phillip P Domeier, Sathi Babu Chodisetti, Chetna Soni, Stephanie L Schell, Melinda J Fasnacht, Yuka Imamura, Anna Salzberg, Ziaur Rahman
Publikováno v:
The Journal of Immunology. 198:201.19-201.19
In systemic lupus erythematosus (SLE), germinal centers can form spontaneously (Spt-GCs) in the absence of foreign antigen and drive high-affinity autoantibody (autoAb) production. Overexpression of Type 1 interferon (IFNα) accelerates autoimmunity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19d1c6133542cfc6e0f411da7aac58ed
https://doi.org/10.4049/jimmunol.198.supp.201.19
https://doi.org/10.4049/jimmunol.198.supp.201.19