Výsledky vyhledávání - "Melinda H Spooner"

Akademický článek

Time course of western diet (WD) induced nonalcoholic steatohepatitis (NASH) in female and male Ldlr-/- mice.

Autor: Melinda H Spooner, Manuel Garcia-Jaramillo, K Denise Apperson, Christiane V Löhr, Donald B Jump

Publikováno v: PLoS ONE, Vol 18, Iss 10, p e0292432 (2023)

BackgroundNonalcoholic fatty liver disease (NAFLD) is a global health problem. Identification of factors contributing to the onset and progression of NAFLD have the potential to direct novel strategies to combat NAFLD.MethodsWe examined the time cour

Externí odkaz: https://doaj.org/article/53a9654b84ec44cebf38a448fccc953d

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Akademický článek

Lipidomic and transcriptomic analysis of western diet-induced nonalcoholic steatohepatitis (NASH) in female Ldlr -/- mice.

Autor: Manuel Garcia-Jaramillo, Melinda H Spooner, Christiane V Löhr, Carmen P Wong, Weijian Zhang, Donald B Jump

Publikováno v: PLoS ONE, Vol 14, Iss 4, p e0214387 (2019)

BackgroundNonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease worldwide, particularly in obese and type 2 diabetic individuals. NAFLD ranges in severity from benign steatosis to nonalcoholic steatohepatitis (NASH); and N

Externí odkaz: https://doaj.org/article/e441729982ab453c99a9a68bd9549d92

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Nonalcoholic Fatty Liver Disease and Omega-3 Fatty Acids: Mechanisms and Clinical Use

Autor: Melinda H. Spooner, Donald B. Jump

Publikováno v: Annual Review of Nutrition. 43

Nonalcoholic fatty liver disease (NAFLD) is the most common chronic fatty liver disease worldwide, particularly in obese and type 2 diabetic individuals. Currently, there are no therapies for NAFLD that have been approved by the US Food and Drug Admi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::48cb51732415e89c3bd46c33da659043
https://doi.org/10.1146/annurev-nutr-061021-030223

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Akademický článek

A Lipidomic Analysis of Docosahexaenoic Acid (22:6, ω3) Mediated Attenuation of Western Diet Induced Nonalcoholic Steatohepatitis in Male Ldlr -/- Mice

Autor: Manuel García-Jaramillo, Kelli A. Lytle, Melinda H. Spooner, Donald B. Jump

Publikováno v: Metabolites, Vol 9, Iss 11, p 252 (2019)

Nonalcoholic fatty liver disease (NAFLD) is a major public health problem worldwide. NAFLD ranges in severity from benign steatosis to nonalcoholic steatohepatitis (NASH), cirrhosis, and primary hepatocellular cancer (HCC). Obesity and type 2 diabete

Externí odkaz: https://doaj.org/article/95aa1cd29fe24676a978ddd5e458af50

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Omega-3 fatty acids and nonalcoholic fatty liver disease in adults and children

Autor: Melinda H. Spooner, Donald B. Jump

Publikováno v: Current Opinion in Clinical Nutrition & Metabolic Care. 22:103-110

PURPOSE OF REVIEW: Nonalcoholic fatty liver disease (NAFLD) is the most common chronic fatty liver disease worldwide. The incidence of NAFLD parallels the prevalence of obesity. Moreover, NAFLD can progress to nonalcoholic steatohepatitis (NASH), cir

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fa13a12499e2d0b6d00c1ca8e606fae
https://doi.org/10.1097/mco.0000000000000539

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Differences in Maternal Immunoglobulins within Mother’s Own Breast Milk and Donor Breast Milk and across Digestion in Preterm Infants

Autor: Veronique Demers-Mathieu, Robert K. Huston, Rachel L Martin, Andi M Markell, Melinda H. Spooner, Elizabeth A. McCulley, David C. Dallas

Publikováno v: Nutrients
Nutrients, Vol 11, Iss 4, p 920 (2019)
Volume 11
Issue 4

Maternal antibody transfer to the newborn provides essential support for the infant&rsquo
s naï
ve immune system. Preterm infants normally receive maternal antibodies through mother&rsquo
s own breast milk (MBM) or, when mothers ar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a0ffaf929413001dc02bbf6872013dc
http://europepmc.org/articles/PMC6521323

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Lipidomic and transcriptomic analysis of western diet-induced nonalcoholic steatohepatitis (NASH) in female Ldlr -/- mice

Autor: Weijian Zhang, Christiane V. Löhr, Melinda H. Spooner, Carmen P. Wong, Manuel García-Jaramillo, Donald B. Jump

Publikováno v: PLoS ONE, Vol 14, Iss 4, p e0214387 (2019)
PLoS ONE

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c6abe941d589fc2bbc518ae90e574ef
https://doaj.org/article/e441729982ab453c99a9a68bd9549d92

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A Lipidomic Analysis of Docosahexaenoic Acid (22:6, ω3) Mediated Attenuation of Western Diet Induced Nonalcoholic Steatohepatitis in Male Ldlr -/- Mice

Autor: Kelli A. Lytle, Melinda H. Spooner, Donald B. Jump, Manuel García-Jaramillo

Publikováno v: Metabolites, Vol 9, Iss 11, p 252 (2019)
Metabolites
Volume 9
Issue 11

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::958ba62db07f82512f3e50497bc8bc9f
https://doi.org/10.3390/metabo9110252

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Akademický článek

Early transcriptome changes associated with western diet induced NASH in Ldlr−/− mice points to activation of hepatic macrophages and an acute phase response

Autor: Jyothi Padiadpu, Melinda H. Spooner, Zhipeng Li, Nolan Newman, Christiane V. Löhr, K. Denise Apperson, Amiran Dzutsev, Giorgio Trinchieri, Natalia Shulzhenko, Andrey Morgun, Donald B. Jump

Publikováno v: Frontiers in Nutrition, Vol 10 (2023)

BackgroundNonalcoholic fatty liver disease (NAFLD) is a global health problem. Identifying early gene indicators contributing to the onset and progression of NAFLD has the potential to develop novel targets for early therapeutic intervention. We repo

Externí odkaz: https://doaj.org/article/46edeae843a44a259ad0dbc2f51e195b

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