Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Melinda Elaine Brunstein"'
Autor:
Jonas Benjamin Michaelis, Melinda Elaine Brunstein, Süleyman Bozkurt, Ludovico Alves, Martin Wegner, Manuel Kaulich, Christian Pohl, Christian Münch
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Mitophagy activation is mediated by mitochondrial depolarization. Here, the authors show that mitochondrial protein misfolding can activate mitophagy in a depolarization-independent manner mediated by a protein import reduction.
Externí odkaz:
https://doaj.org/article/28bd4ad93a744efda167cac0232e31a7
Autor:
Oliver Daniel Schwich, Nicole Blümel, Mario Keller, Marius Wegener, Samarth Thonta Setty, Melinda Elaine Brunstein, Ina Poser, Igor Ruiz De Los Mozos, Beatrix Suess, Christian Münch, François McNicoll, Kathi Zarnack, Michaela Müller-McNicoll
Publikováno v:
Genome Biology, Vol 22, Iss 1, Pp 1-34 (2021)
Abstract Background Alternative polyadenylation (APA) refers to the regulated selection of polyadenylation sites (PASs) in transcripts, which determines the length of their 3′ untranslated regions (3′UTRs). We have recently shown that SRSF3 and S
Externí odkaz:
https://doaj.org/article/636b189fddc14c0eaedf12314fffd4e1
Autor:
Anshu Bhattacharya, Rukmini Mukherjee, Santosh Kumar Kuncha, Melinda Elaine Brunstein, Rajeshwari Rathore, Stephan Junek, Christian Münch, Ivan Dikic
Publikováno v:
Nature Cell Biology
Acute lysosomal membrane damage reduces the cellular population of functional lysosomes. However, these damaged lysosomes have a remarkable recovery potential independent of lysosomal biogenesis and remain unaffected in cells depleted in TFEB and TFE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d43b631724bef9abad34580378bf937
https://hdl.handle.net/21.11116/0000-000C-F2D5-2
https://hdl.handle.net/21.11116/0000-000C-F2D5-2
Autor:
Jonas Benjamin, Michaelis, Melinda Elaine, Brunstein, Süleyman, Bozkurt, Ludovico, Alves, Martin, Wegner, Manuel, Kaulich, Christian, Pohl, Christian, Münch
Publikováno v:
Nature communications. 13(1)
Mitophagy is essential to maintain mitochondrial function and prevent diseases. It activates upon mitochondria depolarization, which causes PINK1 stabilization on the mitochondrial outer membrane. Strikingly, a number of conditions, including mitocho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::adcb71e77e1d4af91ff61e5c5df21e86
https://pubmed.ncbi.nlm.nih.gov/36056001
https://pubmed.ncbi.nlm.nih.gov/36056001