Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Melinda D. Treadwell"'
Autor:
Melinda D. Treadwell
This chapter describes three specific case examples of ethical challenges presented to stakeholders developing occupational and environmental health-protective standards. It differentiates between the approaches used to address bias in each of the il
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e5a737b68bf59f68dfd747d9aa5df71
https://doi.org/10.4324/9780429085826-9
https://doi.org/10.4324/9780429085826-9
Autor:
Melinda D. Treadwell
This chapter describes some of the ethical challenges associated with occupational and environmental policy development for toxins, including the difficulty in reaching consensus for health-protective standards when faced with scientific uncertainty.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9207f6b250be59bdeaa0ada12fa92221
https://doi.org/10.4324/9780429085826-8
https://doi.org/10.4324/9780429085826-8
Autor:
Melinda D. Treadwell, Aaron Barchowsky, Kevin E. Driscoll, Brooke T. Mossman, Yvonne M. W. Janssen
Publikováno v:
Proceedings of the National Academy of Sciences. 92:8458-8462
Nuclear factor kappa B (NF-kappa B) is a transcription factor regulating expression of genes intrinsic to inflammation and cell proliferation--features of asbestos-associated diseases. In studies here, crocidolite asbestos caused protracted and dose-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0848eed23709a949d87aa135611b8a2
https://doi.org/10.1073/pnas.92.18.8458
https://doi.org/10.1073/pnas.92.18.8458
Autor:
Claudine A. Louis, Joshua W. Hamilton, Michael J. Reed, Steven R. Hunt, Melinda D. Treadwell, Kristen A. Doherty
Publikováno v:
Molecular Carcinogenesis. 8:34-43
Our laboratory is interested in whether chemical carcinogen—induced DNA damage is nonrandomly distributed in the genome, i.e., “targeted,” at the level of individual genes. To examine this, we have been investigating whether carcinogen treatmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca2e4f4e977b0aaba74391426f68fa31
https://doi.org/10.1002/mc.2940080109
https://doi.org/10.1002/mc.2940080109
Autor:
Ronald J. Krieser, Melinda D. Treadwell, Robert R. Roussel, Brooke T. Mossman, Aaron Barchowsky
Publikováno v:
Toxicology and applied pharmacology. 152(2)
An elongated endothelial cell phenotype, which demonstrated increased ICAM-1-dependent neutrophil adherence, was induced when these cells were exposed to noncytotoxic concentrations of asbestos (Treadwell et al., Toxicol. Appl. Pharmacol. 139, 62-70,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b696a95ae1345919a490d1d8bedd5fc3
https://pubmed.ncbi.nlm.nih.gov/9853007
https://pubmed.ncbi.nlm.nih.gov/9853007
Publikováno v:
Toxicology and applied pharmacology. 139(1)
Inhalation of asbestos may activate the pulmonary endothelium to promote an inflammatory cell phenotype that participates in the development of pulmonary fibrosis. However, little is known about the effects of asbestos on endothelial cell function. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d85caf8e0837697444465badb8178efd
https://pubmed.ncbi.nlm.nih.gov/8685910
https://pubmed.ncbi.nlm.nih.gov/8685910
Publikováno v:
Free radical biologymedicine. 21(6)
Chronic exposure to low levels of environmentally derived arsenite are associated with vascular diseases, such as arteriosclerosis. However, the cellular and molecular mechanisms for vascular disease in response to arsenic are not known. These studie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c356d514487b36dcb238b2efce4fcb3
https://pubmed.ncbi.nlm.nih.gov/8902524
https://pubmed.ncbi.nlm.nih.gov/8902524