Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Melinda A. Brindley"'
Autor:
Gokul Raghunath, Elizabeth H. Abbott, Mariana Marin, Hui Wu, Judith Mary Reyes Ballista, Melinda A. Brindley, Gregory B. Melikyan
Publikováno v:
Biomolecules, Vol 14, Iss 5, p 570 (2024)
Host restriction factor SERINC5 (SER5) incorporates into the HIV-1 membrane and inhibits infectivity by a poorly understood mechanism. Recently, SER5 was found to exhibit scramblase-like activity leading to the externalization of phosphatidylserine (
Externí odkaz:
https://doaj.org/article/0753e4b4cf944120b0402b32639dbcfa
Autor:
M. Osman Sheikh, Chantelle J. Capicciotti, Lin Liu, Jeremy Praissman, Dahai Ding, Daniel G. Mead, Melinda A. Brindley, Tobias Willer, Kevin P. Campbell, Kelley W. Moremen, Lance Wells, Geert-Jan Boons
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Matriglycan, a repeating disaccharide on α-dystroglycan, is the receptor for Lassa virus and specific extracellular matrix proteins. Here, the authors demonstrate that matriglycan, in a length-dependent tunable manner, is both necessary and sufficie
Externí odkaz:
https://doaj.org/article/6f16e38680614cf4be0f9a79a71c7b0f
Autor:
Judith Mary Reyes Ballista, Kerri L. Miazgowicz, Marissa D. Acciani, Ariana R. Jimenez, Ryan S. Belloli, Katherine E. Havranek, Melinda A. Brindley
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Chikungunya virus (CHIKV) is the causative agent of the human disease chikungunya fever, characterized by debilitating acute and chronic arthralgia. No licensed vaccines or antivirals are currently available for CHIKV. Therefore, the prevention of at
Externí odkaz:
https://doaj.org/article/7b247b08e2b8440a8910d6bdce1280a8
Autor:
Christine M. Reitmayer, Ashutosh K. Pathak, Laura C. Harrington, Melinda A. Brindley, Lauren J. Cator, Courtney C. Murdock
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-10 (2021)
Reitmayer, Murdock, and colleagues examine the relationship between mating strategy and immune response in a human disease vector: the yellow fever mosquito. Their findings indicate that harmonic convergence is predictive of offspring immune response
Externí odkaz:
https://doaj.org/article/5249535be2794fefb82cf0d4ba820748
Autor:
Hin Chu, Bingjie Hu, Xiner Huang, Yue Chai, Dongyan Zhou, Yixin Wang, Huiping Shuai, Dong Yang, Yuxin Hou, Xi Zhang, Terrence Tsz-Tai Yuen, Jian-Piao Cai, Anna Jinxia Zhang, Jie Zhou, Shuofeng Yuan, Kelvin Kai-Wang To, Ivy Hau-Yee Chan, Ko-Yung Sit, Dominic Chi-Chung Foo, Ian Yu-Hong Wong, Ada Tsui-Lin Ng, Tan To Cheung, Simon Ying-Kit Law, Wing-Kuk Au, Melinda A. Brindley, Zhiwei Chen, Kin-Hang Kok, Jasper Fuk-Woo Chan, Kwok-Yung Yuen
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Here, using lung epithelial cells and ex vivo tissue explants, the authors show that, in addition to ACE2, host heparan sulfate is directly involved in SARS-CoV-2 attachment and entry and provide data suggesting that host sialic acids may act as vira
Externí odkaz:
https://doaj.org/article/81bdbff8c7524b069f430bb69d6fb811
Autor:
Melinda A. Brindley
Publikováno v:
mSphere, Vol 6, Iss 1 (2021)
Melinda A. Brindley works in the field of virology with specific interests in understanding how viruses enter cells. In this mSphere of Influence article, she reflects on how the paper “Vaccinia virus uses macropinocytosis and apoptotic mimicry to
Externí odkaz:
https://doaj.org/article/de4654997d214aa5b4e4ac2abd5faa30
Autor:
Michelle V. Evans, Justine C. Shiau, Nicole Solano, Melinda A. Brindley, John M. Drake, Courtney C. Murdock
Publikováno v:
Parasites & Vectors, Vol 11, Iss 1, Pp 1-13 (2018)
Abstract Background Mosquitoes are strongly influenced by environmental temperatures, both directly and indirectly via carry-over effects, a phenomenon by which adult phenotypes are shaped indirectly by the environmental conditions experienced in pre
Externí odkaz:
https://doaj.org/article/7d9c801876594839a1ce6e4c83d0f3ae
Autor:
Zunlong Ke, Joshua D. Strauss, Cheri M. Hampton, Melinda A. Brindley, Rebecca S. Dillard, Fredrick Leon, Kristen M. Lamb, Richard K. Plemper, Elizabeth R. Wright
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Virus assembly is technically challenging to study. Here the authors use cryo-electron tomography of measles virus-infected human cells to determine native-state virus structure and they locate well-ordered M lattices that organize viral glycoprotein
Externí odkaz:
https://doaj.org/article/8cf6586c2905457c8522577aa118213b
Publikováno v:
Viruses, Vol 11, Iss 1, p 20 (2018)
Zika virus (ZIKV) is an emerging flavivirus responsible for a major epidemic in the Americas beginning in 2015. ZIKV associated with maternal infection can lead to neurological disorders in newborns, including microcephaly. Although there is an abund
Externí odkaz:
https://doaj.org/article/2c6cf00666e640f0b3acd896c50e1426
Publikováno v:
Pathogens, Vol 8, Iss 1, p 1 (2018)
Lassa virus (LASV) is an Old World arenavirus, endemic to West Africa, capable of causing hemorrhagic fever. Currently, there are no approved vaccines or effective antivirals for LASV. However, thorough understanding of the LASV glycoprotein and entr
Externí odkaz:
https://doaj.org/article/f934e985ff9644e5a5358ce6e0f08743