Zobrazeno 1 - 10
of 143
pro vyhledávání: '"Melinda A, Beck"'
Autor:
Marwa Abd Alhadi, Lilach M. Friedman, Erik A. Karlsson, Liel Cohen-Lavi, Anat Burkovitz, Stacey Schultz-Cherry, Terry L. Noah, Samuel S. Weir, Lester M. Shulman, Melinda A. Beck, Tomer Hertz
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 3 (2023)
ABSTRACT Obesity is a risk factor for severe disease and mortality for both influenza and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. While previous studies show that individuals with obesity generate antibody responses fo
Externí odkaz:
https://doaj.org/article/5f3c29fb1aab4827b4cefeb07cc536d6
Autor:
Randall C. Gunther, Vanthana Bharathi, Stephen D. Miles, Lauryn R. Tumey, Clare M. Schmedes, Kohei Tatsumi, Meagan D. Bridges, David Martinez, Stephanie A. Montgomery, Melinda A. Beck, Eric Camerer, Nigel Mackman, Silvio Antoniak
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
BackgroundInnate immune responses to influenza A virus (IAV) infection are initiated in part by toll-like receptor 3 (TLR3). TLR3-dependent signaling induces an antiviral immune response and an NFκB-dependent inflammatory response. Protease-activate
Externí odkaz:
https://doaj.org/article/9ce01fde26334c13975a5e0be80b3539
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Externí odkaz:
https://doaj.org/article/f6c77fb025a34232b6c233535faf0271
Autor:
Nicolás Bravo-Vasquez, Erik A. Karlsson, Pedro Jimenez-Bluhm, Victoria Meliopoulos, Bryan Kaplan, Shauna Marvin, Valerie Cortez, Pamela Freiden, Melinda A. Beck, Stacey Schultz-Cherry
Publikováno v:
Emerging Infectious Diseases, Vol 23, Iss 2, Pp 241-251 (2017)
Phylogenetic analysis of the influenza hemagglutinin gene (HA) has suggested that commercial pigs in Chile harbor unique human seasonal H1-like influenza viruses, but further information, including characterization of these viruses, was unavailable.
Externí odkaz:
https://doaj.org/article/b14ef961f83a4540bc3385a0afe44a8f
Publikováno v:
Annual Review of Nutrition. 42:67-89
The COVID-19 pandemic demonstrates that obesity alone, independent of comorbidities, is a significant risk factor for severe outcomes from infection. This susceptibility mirrors a similar pattern with influenza infection; that is, obesity is a unique
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0456a905d11a39b1cd80fb2f41870d57
https://doi.org/10.1146/annurev-nutr-062320-115937
https://doi.org/10.1146/annurev-nutr-062320-115937
Autor:
Ichiro Misumi, Joshua Starmer, Toru Uchimura, Melinda A. Beck, Terry Magnuson, Jason K. Whitmire
Publikováno v:
Cell Reports, Vol 27, Iss 2, Pp 514-524.e5 (2019)
Summary: Obesity in humans is associated with poorer health outcomes after infections compared with non-obese individuals. Here, we examined the effects of white adipose tissue and obesity on T cell responses to viral infection in mice. We show that
Externí odkaz:
https://doaj.org/article/fcccce7b602a4eafbd7e9a94bec05b4a
Autor:
Amy R. Johnson, Yuanyuan Qin, Alyssa J. Cozzo, Alex J. Freemerman, Megan J. Huang, Liyang Zhao, Brante P. Sampey, J. Justin Milner, Melinda A. Beck, Blossom Damania, Naim Rashid, Joseph A. Galanko, Douglas P. Lee, Matthew L. Edin, Darryl C. Zeldin, Patrick T. Fueger, Brittney Dietz, Andreas Stahl, Ying Wu, Karen L. Mohlke, Liza Makowski
Publikováno v:
Molecular Metabolism, Vol 5, Iss 7, Pp 506-526 (2016)
Objective: A novel approach to regulate obesity-associated adipose inflammation may be through metabolic reprogramming of macrophages (MΦs). Broadly speaking, MΦs dependent on glucose are pro-inflammatory, classically activated MΦs (CAM), which co
Externí odkaz:
https://doaj.org/article/3500912ba36c44dabe717f2ead379674
Autor:
Shufa Du, Melinda A. Beck, Barry M. Popkin, Taghred Alghaith, Christopher H. Herbst, William D. Green, Reem F. Alsukait, Mohammed Alluhidan, Meera Shekar, Nahar Alazemi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7af828cd3bbc0a69c90ede617d424f62
https://doi.org/10.1596/978-1-4648-1828-8_ch6
https://doi.org/10.1596/978-1-4648-1828-8_ch6
Autor:
Nancie J. MacIver, J. Justin Milner, Saame Raza Shaikh, Qing Shi, Melinda A. Beck, Abrar E. Al-Shaer, Kymberly M Gowdy, William R. Green
Publikováno v:
Journal of Leukocyte Biology. 111:147-159
Obesity is an independent risk factor for morbidity and mortality in response to influenza infection. However, the underlying mechanisms by which obesity impairs immunity are unclear. Herein, we investigated the effects of diet-induced obesity on pul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::610b28965a4124edac31bbe1593a1156
https://doi.org/10.1002/jlb.4a0120-075rr
https://doi.org/10.1002/jlb.4a0120-075rr
Autor:
Vanthana Bharathi, Kohei Tatsumi, Tracy Stokol, Nigel Mackman, Grant J. Egnatz, Alyson C. Auriemma, Silvio Antoniak, Joseph S. Palumbo, Melinda A. Beck, Clare M. Schmedes, John H. Griffin
Publikováno v:
Journal of Thrombosis and Haemostasis
Background Protease‐activated receptor 1 (PAR1) is expressed in various immune cells and in the lung. We showed that PAR1 plays a role in Coxsackievirus B3 infection by enhancing toll‐like receptor 3‐dependent interferon‐β expression in card
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c15d628d108303d9143b27114b1fa369
https://doi.org/10.1111/jth.15221
https://doi.org/10.1111/jth.15221