Zobrazeno 1 - 10
of 427
pro vyhledávání: '"Melina R. Kibbe"'
Autor:
Mary M. McDermott, Christopher R. Martens, Kathryn J. Domanchuk, Dongxue Zhang, Clara B. Peek, Michael H. Criqui, Luigi Ferrucci, Philip Greenland, Jack M. Guralnik, Karen J. Ho, Melina R. Kibbe, Kate Kosmac, Donald Lloyd-Jones, Charlotte A. Peterson, Robert Sufit, Lu Tian, Stephanie Wohlgemuth, Lihui Zhao, Pei Zhu, Christiaan Leeuwenburgh
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract People with lower extremity peripheral artery disease (PAD) have increased oxidative stress, impaired mitochondrial activity, and poor walking performance. NAD+ reduces oxidative stress and is an essential cofactor for mitochondrial respirat
Externí odkaz:
https://doaj.org/article/2c373f254eb346318d878694e2b1a44e
Autor:
Kyle C. Alexander, Carlton W. Anderson, Chris B. Agala, Panagiotis Tasoudis, Elizabeth N. Collins, Yiwen Ding, John W. Blackwell, Danielle E. Willcox, Behzad S. Farivar, Melina R. Kibbe, John S. Ikonomidis, Adam W. Akerman
Publikováno v:
Journal of Clinical Medicine, Vol 13, Iss 6, p 1548 (2024)
Background: Thoracic aortic aneurysms (TAAs) associated with Marfan syndrome (MFS) are unique in that extracellular matrix metalloproteinase inducer (EMMPRIN) levels do not behave the way they do in other cardiovascular pathologies. EMMPRIN is shed i
Externí odkaz:
https://doaj.org/article/6fbe1bc30c754c68aea34c5d8916e3e2
Autor:
Vina Y. Chhaya, Sophia Maragos, Ruomeng Qiu, Simon A. Egner, Mark R. Karver, Samuel I. Stupp, Nick D. Tsihlis, Melina R. Kibbe
Publikováno v:
JVS - Vascular Science, Vol 4, Iss , Pp 100152- (2023)
Externí odkaz:
https://doaj.org/article/1df98e3b8b7d4f62814543fbe57a393c
Autor:
Michael M. Hammond, Bonnie Spring, W. Jack Rejeski, Robert Sufit, Michael H. Criqui, Lu Tian, Lihui Zhao, Shujun Xu, Melina R. Kibbe, Christiaan Leeuwenburgh, Todd Manini, Daniel E. Forman, Diane Treat‐Jacobson, Tamar S. Polonsky, Lydia Bazzano, Luigi Ferrucci, Jack Guralnik, Donald M. Lloyd‐Jones, Mary M. McDermott
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 15 (2022)
Background In people with peripheral artery disease, post hoc analyses of the LITE (Low Intensity Exercise Intervention in Peripheral Artery Disease) randomized trial were conducted to evaluate the effects of walking exercise at a pace inducing ische
Externí odkaz:
https://doaj.org/article/d38fd05c7d7b44f8b4df9a9c7feee045
Publikováno v:
Journal of Translational Medicine, Vol 18, Iss 1, Pp 1-16 (2020)
Abstract Background Smoke inhalation injury increases overall burn mortality by up to 20 times. Current therapy remains supportive with a failure to identify an optimal or targeted treatment protocol for smoke inhalation injury. The goal of this revi
Externí odkaz:
https://doaj.org/article/25487ec5a5c94197999a61ebac85be80
Autor:
Emily R. Newton, David C. Gillis, Kui Sun, Brooke R. Dandurand, Robin Siletzky, Suvendu Biswas, Mark R. Karver, Nick D. Tsihlis, Samuel I. Stupp, Melina R. Kibbe
Publikováno v:
Advanced NanoBiomed Research, Vol 1, Iss 7, Pp n/a-n/a (2021)
Herein the hypothesis that nitric oxide–bearing collagen‐targeted nanofibers will target vascular injury and inhibit neointimal hyperplasia in an atherosclerotic rat model is tested. Western blot confirms the apolipoprotein E (ApoE) knockout (‐
Externí odkaz:
https://doaj.org/article/3642766316594f008d05e493fbf1b020
Autor:
Mary M. McDermott, Lu Tian, Michael H. Criqui, Luigi Ferrucci, Philip Greenland, Jack M. Guralnik, Melina R. Kibbe, Lingyu Li, Robert Sufit, Lihui Zhao, Tamar S. Polonsky
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 12 (2021)
Background In people with lower‐extremity peripheral artery disease, the effects of exercise on patient‐reported outcomes remain unclear. Methods and Results Four hundred four people with peripheral artery disease in 3 clinical trials were random
Externí odkaz:
https://doaj.org/article/92568e8ae9b84d82865c50904a51008a
Autor:
Hussein A. Kassam, Edward M. Bahnson, Ana Cartaya, Wulin Jiang, Michael J. Avram, Nick D. Tsihlis, Samuel I. Stupp, Melina R. Kibbe
Publikováno v:
Pharmacology Research & Perspectives, Vol 8, Iss 6, Pp n/a-n/a (2020)
Abstract Atherosclerosis remains a leading cause of death and disability around the world and a major driver of health care spending. Nanomaterials have gained widespread attention due to their promising potential for clinical translation and use. We
Externí odkaz:
https://doaj.org/article/37a3374d8d0f4c2c89937de28286c743
Autor:
Kate Kosmac, Marta Gonzalez‐Freire, Mary M. McDermott, Sarah H. White, R. Grace Walton, Robert L. Sufit, Lu Tian, Lingyu Li, Melina R. Kibbe, Michael H. Criqui, Jack M. Guralnik, Tamar S. Polonsky, Christiaan Leeuwenburgh, Luigi Ferrucci, Charlotte A. Peterson
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 10 (2020)
Background Peripheral artery disease (PAD) is a manifestation of atherosclerosis characterized by reduced blood flow to the lower extremities and mobility loss. Preliminary evidence suggests PAD damages skeletal muscle, resulting in muscle impairment
Externí odkaz:
https://doaj.org/article/29819e9cb8a54c9cb5df3b007eb2c817
Autor:
Marta Gonzalez‐Freire, A. Zenobia Moore, Charlotte A. Peterson, Kate Kosmac, Mary M. McDermott, Robert L. Sufit, Jack M. Guralnik, Tamar Polonsky, Lu Tian, Melina R. Kibbe, Michael H. Criqui, Lingyu Li, Christian Leeuwenburgh, Luigi Ferrucci
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 7 (2020)
Background Patients with peripheral artery disease (PAD) undergo frequent episodes of ischemia‐reperfusion in lower extremity muscles that may negatively affect mitochondrial health and are associated with impaired mobility. We hypothesized that sk
Externí odkaz:
https://doaj.org/article/a14b7486f8754228927ca7bad4ee1bdd