Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Melina Jones"'
Autor:
Myoung-Hwa Lee, Ph.D., Wenxue Li, Ph.D., Kevon Sampson, M.A., Melina Jones, Ph.D., Joseph Steiner, Ph.D., Avindra Nath, M.D.
Publikováno v:
Neurotherapeutics, Vol 21, Iss 4, Pp e00412- (2024)
Externí odkaz:
https://doaj.org/article/5cf47864162940a7b0a87838a22a3f16
Effect of CXCR2 Inhibition on Behavioral Outcomes and Pathology in Rat Model of Neuromyelitis Optica
Autor:
Melina Jones, Michael J. Levy
Publikováno v:
Journal of Immunology Research, Vol 2018 (2018)
Journal of Immunology Research
Journal of Immunology Research
Objective. To reduce immune-mediated damage in a rat model of neuromyelitis optica (NMO) by blocking neutrophil migration using SCH527123, a drug that inhibits CXCR2. Background. Neuromyelitis optica is a relapsing autoimmune disease that preferentia
Autor:
Michael J. Levy, Nicolas Collongues, Makoto Kinoshita, Melina Jones, Jérôme De Seze, Yuji Nakatsuji
Publikováno v:
Multiple Sclerosis and Related Disorders. 1:174-179
Neuromyelitis optica (NMO) is a recurrent neuroinflammatory disease of the optic nerves and spinal cord associated with the anti-aquaporin-4 (AQP4) antibody biomarker, NMO-IgG. As clinical and scientific research interest in NMO grows, the need for a
Publikováno v:
Magnetic Resonance in Medicine. 67:750-759
Diffusion tensor imaging has been widely used in studying rodent models of white matter diseases. In this study, we examined the differences between in vivo and ex vivo fractional anisotropy and diffusivity measurements in the mouse cuprizone model.
Publikováno v:
Magnetic Resonance in Medicine. 67:98-109
High resolution diffusion tensor images of the mouse brain were acquired using the pulsed gradient spin echo sequence and the oscillating gradient spin echo sequence. The oscillating gradient spin echo tensor images demonstrated frequency-dependent c
Autor:
Peter A. Calabresi, Cosmin A. Tegla, Melina Jones, Carlos A. Pardo, Katharine A. Whartenby, Cynthia A. DeBoy, Horea Rus, Cornelia Cudrici, Donald Small
Publikováno v:
Experimental and Molecular Pathology. 89:109-116
Inflammatory cell infiltration and resident microglial activation within the central nervous system (CNS) are pathological events in multiple sclerosis (MS) and experimental autoimmune encephalomyelitis (EAE). While MS therapies target the peripheral
Autor:
Melina Jones, Cynthia A. DeBoy, Paul N. Hoffman, Peter A. Calabresi, Bennett A. Landman, Seth A. Smith, Jiangyang Zhang, Jonathan A.D. Farrell, Peter C.M. van Zijl, Daniel S. Reich
Publikováno v:
Magnetic Resonance in Medicine. 63:1323-1335
Parallel and perpendicular diffusion properties of water in the rat spinal cord were investigated 3 and 30 days after dorsal root axotomy, a specific insult resulting in early axonal degeneration followed by later myelin damage in the dorsal column w
Autor:
Jiangyang Zhang, John W. Griffin, Cynthia A. DeBoy, Kazim A. Sheikh, Peter A. Calabresi, Melina Jones, Paul N. Hoffman, Susumu Mori, Michael I. Miller, Daniel S. Reich, Jonathan A.D. Farrell
Publikováno v:
The Journal of Neuroscience. 29:3160-3171
Diffusion tensor imaging (DTI) and immunohistochemistry were used to examine axon injury in the rat spinal cord after unilateral L2–L4dorsal root axotomy at multiple time points (from 16 h to 30 d after surgery). Three days after axotomy, DTI revea
Autor:
Melina Jones, Douglas A. Kerr, Jerome J. Graber, Adam I. Kaplin, Peter A. Calabresi, S. Rameeza Allie, Tongguang Wang, Avi Nath, Katherine M. Mullen, Chitra Krishnan
Publikováno v:
Journal of Neuroimmunology. 196:124-132
CSF IL-6 is elevated in transverse myelitis (TM) and predicts disability. Since IL-17 regulates cytokines (TNFα, IL-1β and IL-6) known to stimulate IL-6 production by astrocytes, we sought to determine whether IL-17 was increased in TM and MS compa
The rat optic nerve is a useful model for stem cell regeneration research. Direct injection into the rat optic nerve allows delivery into the central nervous system in a minimally-invasive surgery without bone removal. This technique describes an app
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17c08d9b6ee6b6422e378ddac9098335
https://europepmc.org/articles/PMC4542817/
https://europepmc.org/articles/PMC4542817/