Zobrazeno 1 - 10
of 199
pro vyhledávání: '"Melike Pekmezci"'
Autor:
S. John Liu, Tim Casey-Clyde, Nam Woo Cho, Jason Swinderman, Melike Pekmezci, Mark C. Dougherty, Kyla Foster, William C. Chen, Javier E. Villanueva-Meyer, Danielle L. Swaney, Harish N. Vasudevan, Abrar Choudhury, Joanna Pak, Jonathan D. Breshears, Ursula E. Lang, Charlotte D. Eaton, Kamir J. Hiam-Galvez, Erica Stevenson, Kuei-Ho Chen, Brian V. Lien, David Wu, Steve E. Braunstein, Penny K. Sneed, Stephen T. Magill, Daniel Lim, Michael W. McDermott, Mitchel S. Berger, Arie Perry, Nevan J. Krogan, Marlan R. Hansen, Matthew H. Spitzer, Luke Gilbert, Philip V. Theodosopoulos, David R. Raleigh
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Mechanisms specifying cancer cell states and response to therapy are incompletely understood. Here we show epigenetic reprogramming shapes the cellular landscape of schwannomas, the most common tumors of the peripheral nervous system. We fin
Externí odkaz:
https://doaj.org/article/6c3cb10a1a664ce0a55f363c96e7591d
Autor:
Harish N. Vasudevan, Emily Payne, Cyrille L. Delley, S. John Liu, Kanish Mirchia, Matthew J. Sale, Sydney Lastella, Maria Sacconi Nunez, Calixto-Hope G. Lucas, Charlotte D. Eaton, Tim Casey-Clyde, Stephen T. Magill, William C. Chen, Steve E. Braunstein, Arie Perry, Line Jacques, Alyssa T. Reddy, Melike Pekmezci, Adam R. Abate, Frank McCormick, David R. Raleigh
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Schwann cell tumors are the most common cancers of the peripheral nervous system and can arise in patients with neurofibromatosis type-1 (NF-1) or neurofibromatosis type-2 (NF-2). Functional interactions between NF1 and NF2 and broader mecha
Externí odkaz:
https://doaj.org/article/a34dc09304394fd3ae1c29c108fd0bbd
Autor:
Carlen A. Yuen, Silin Bao, Xiao-Tang Kong, Merryl Terry, Alexander Himstead, Michelle Zheng, Melike Pekmezci
Publikováno v:
Biomedicines, Vol 12, Iss 9, p 2042 (2024)
The World Health Organization’s (WHO) classification of central nervous system (CNS) tumors is continually being refined to improve the existing diagnostic criteria for high-grade gliomas (HGGs), including glioblastoma. In 2021, advances in molecul
Externí odkaz:
https://doaj.org/article/4618db11b5c64bfc9565060af5066242
Autor:
Ibrahim Kulac, Irem Yenidogan, Banu Oflaz Sozmen, Arzu Baygul, Soonmee Cha, Melike Pekmezci, Tarik Tihan
Publikováno v:
Free Neuropathology, Vol 4 (2023)
Introduction: Pilocytic astrocytoma (PA) is one of the most common primary intracranial neoplasms in childhood with an overall favorable prognosis. Despite decades of experience, there are still diagnostic and treatment challenges and unresolved issu
Externí odkaz:
https://doaj.org/article/5a53ba9767154d33890cafbba45ca8ee
Next-generation sequencing of a large uveal melanoma with whole genome doubling and a PBRM1 mutation
Publikováno v:
American Journal of Ophthalmology Case Reports, Vol 31, Iss , Pp 101861- (2023)
Purpose: To report a large uveal melanoma with extra-scleral extension which underwent spontaneous infarction and its unique molecular signature profile. Observations: An 81-year-old female presented with a blind, painful eye. Intraocular pressure wa
Externí odkaz:
https://doaj.org/article/8a3aa299b636403891797ba64047b797
Autor:
Figen SOYLEMEZOGLU, Buge OZ, Reyhan EGILMEZ, Melike PEKMEZCI, Suheyla BOZKURT, Ayca ERSEN DANYELI, Onder ONGURU, Ibrahim KULAC, Tarik TIHAN,
Publikováno v:
Türk Patoloji Dergisi, Vol 38, Iss 3, Pp 185-204 (2022)
In our manuscript, we propose a common terminology in the Turkish language for the newly adopted WHO classification of the CNS tumors, also known as the WHO CNS 5th edition. We also comment on the applicability of this new scheme in low and middle in
Externí odkaz:
https://doaj.org/article/9922c4313c2244caa833ab59cf74f3cc
Publikováno v:
American Journal of Ophthalmology Case Reports, Vol 29, Iss , Pp 101791- (2023)
Purpose: To describe the clinical, optical coherence tomography (OCT), and histopathological findings of a patient who was found to have ossification of a pre-retinal membrane after multiple surgical repairs for retinal detachment. Methods: The patie
Externí odkaz:
https://doaj.org/article/825b08100a12445d86269b89ed08cb71
Autor:
Maria Carter-Febres, Emily A. Sloan, Melike Pekmezci, Angelica R. Putnam, Luke Linscott, Samuel Cheshier, Kenneth Aldape, Carol S. Bruggers
Publikováno v:
Pediatric Hematology Oncology Journal, Vol 6, Iss 3, Pp 127-131 (2021)
Ependymomas account for nearly 10% of pediatric intracranial tumors. Surgical resection followed by focal radiation constitutes standard management for children older than 1 year when diagnosed. No standard therapy exists for the extremely vulnerable
Externí odkaz:
https://doaj.org/article/b13f690b4c6f4a7d8b7c708276341350
Autor:
Melike Pekmezci, Ramin A. Morshed, Pranathi Chunduru, Balaji Pandian, Jacob Young, Javier E. Villanueva-Meyer, Tarik Tihan, Emily A. Sloan, Manish K. Aghi, Annette M. Molinaro, Mitchel S. Berger, Shawn L. Hervey-Jumper
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract In the management of diffuse gliomas, the identification and removal of tumor at the infiltrative margin remains a central challenge. Prior work has demonstrated that fluorescence labeling tools and radiographic imaging are useful surgical a
Externí odkaz:
https://doaj.org/article/d0f2d439f7c344898da0426b8b2216a6
Autor:
Chenan Zhang, Quinn T. Ostrom, Eleanor C. Semmes, Vijay Ramaswamy, Helen M. Hansen, Libby Morimoto, Adam J. de Smith, Melike Pekmezci, Zalman Vaksman, Hakon Hakonarson, Sharon J. Diskin, Catherine Metayer, The Glioma International Case-Control Study (GICC), Michael D. Taylor, Joseph L. Wiemels, Melissa L. Bondy, Kyle M. Walsh
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-12 (2020)
Abstract Ependymoma is the third most common brain tumor in children, with well-described molecular characterization but poorly understood underlying germline risk factors. To investigate whether genetic predisposition to longer telomere length influ
Externí odkaz:
https://doaj.org/article/120d88ccd2ce41e9885174895144abf6