Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Melike Hacer Ozkan"'
Publikováno v:
Biologicalpharmaceutical bulletin. 44(9)
The vascular action of trimethylamine-N-oxide (TMAO)-the gut microbiota-derived metabolite-in contributing cardiovascular disease is a controversial topic. A recent study has shown that acute exposure of TMAO at moderate concentrations inhibits endot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b922502bc57c09179dfdeda753436fa
https://pubmed.ncbi.nlm.nih.gov/34471050
https://pubmed.ncbi.nlm.nih.gov/34471050
Publikováno v:
AAPS PharmSciTech. 21
Rivaroxaban (RXB) is a class II drug, according to the Biopharmaceutics Classification System. Since its bioavailability is low at high doses, dose proportionality is not achieved for pharmacokinetic parameters. However, when taken with food, its bio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::923373380a76896756917c2622214796
https://doi.org/10.1208/s12249-020-01776-z
https://doi.org/10.1208/s12249-020-01776-z
Autor:
Melike Hacer Ozkan, Serdar Uma
Publikováno v:
Basic & Clinical Pharmacology & Toxicology. 122:570-576
Endothelial IKCa and/or SKCa channels play an important role in the control of vascular tone by participating in endothelium-dependent relaxation. Whether β-AR antagonists, mainly used in hypertension, affect endothelial KCa channel function is unkn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::035c982c20eb91166594908abf232010
https://doi.org/10.1111/bcpt.12949
https://doi.org/10.1111/bcpt.12949
Autor:
Melike Hacer, Ozkan, Serdar, Uma
Publikováno v:
Basicclinical pharmacologytoxicology. 122(6)
Endothelial IK
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::58ec03d77f5e5a26231af8b7e831e5df
https://pubmed.ncbi.nlm.nih.gov/29278444
https://pubmed.ncbi.nlm.nih.gov/29278444
Publikováno v:
Pharmacological Research. 70:60-65
In the present study, we aimed to examine the effect of blockade of L-type Ca(2+) channels (LTCC) and in addition the removal of extracellular Ca(2+), on EFS-induced relaxations in rings of rat mesenteric artery. EFS applied to the tissues precontrac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c23cb0f5a596665dd1f581886bff4157
https://doi.org/10.1016/j.phrs.2013.01.001
https://doi.org/10.1016/j.phrs.2013.01.001
Autor:
Melike Hacer Ozkan, Arzu Demirtola, Zeynep Sevim Ercan, Gökçe Sevim Öztürk, Serdar Moralioglu, Sureyya Barun, I O Ozen, Yusuf Sarioglu, Ismail Mert Vural
Publikováno v:
European Surgical Research. 39:269-274
Aim: Although little is known about the mechanisms, varicocele is considered as one of the factors leading to male infertility. Since reduced motility of the vas deferens was shown to contribute to male infertility, in this study we aimed to investig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a7b3105aba18a85cee754ef65a18cf9
https://doi.org/10.1159/000102592
https://doi.org/10.1159/000102592
Publikováno v:
Journal of Biotechnology. 256:S87
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba0d98334a69158cfe01cb4f8ba6b9ca
https://doi.org/10.1016/j.jbiotec.2017.06.1098
https://doi.org/10.1016/j.jbiotec.2017.06.1098