Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Melike Cokol Cakmak"'
Publikováno v:
PLoS ONE, Vol 15, Iss 7, p e0235929 (2020)
Combinations of three or more drugs are routinely used in various medical fields such as clinical oncology and infectious diseases to prevent resistance or to achieve synergistic therapeutic benefits. The very large number of possible high-order drug
Externí odkaz:
https://doaj.org/article/9f6b1a25276a4bf9891d1b6ea679e137
Autor:
Atefeh Zarepour, Abdurrahim Can Egil, Melike Cokol Cakmak, Monireh Esmaeili Rad, Yuksel Cetin, Seyma Aydinlik, Gozde Ozaydin Ince, Ali Zarrabi
Publikováno v:
Polymers; Volume 15; Issue 2; Pages: 298
Changes in weather conditions and lifestyle lead to an annual increase in the amount of lung cancer, and therefore it is one of the three most common types of cancer, making it important to find an appropriate treatment method. This research aims to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4ee04f8129e6d83026aa5351352828d
Publikováno v:
Colloids and surfaces. B, Biointerfaces. 196
With the development of nanotechnology, various drug delivery systems including inorganic nanoparticles, liposomes, polymers, etc. have been developed over the past decade. Some of these nanoparticles are also forthcoming candidates for the successfu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53a9bbddd94cb17acaf54b19a159c1eb
https://pubmed.ncbi.nlm.nih.gov/32956996
https://pubmed.ncbi.nlm.nih.gov/32956996
Autor:
Melike, Cokol-Cakmak, Murat, Cokol
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1939
Drugs may have synergistic or antagonistic interactions when combined. Checkerboard assays, where two drugs are combined in many doses, allow sensitive measurement of drug interactions. Here, we describe a protocol to measure the pairwise interaction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4496160e4669665f91c6e67dfc35142f
https://pubmed.ncbi.nlm.nih.gov/30848453
https://pubmed.ncbi.nlm.nih.gov/30848453
Autor:
Murat Cokol, Melike Cokol-Cakmak
Publikováno v:
Methods in Molecular Biology ISBN: 9781493990887
Drugs may have synergistic or antagonistic interactions when combined. Checkerboard assays, where two drugs are combined in many doses, allow sensitive measurement of drug interactions. Here, we describe a protocol to measure the pairwise interaction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2acc921be36329587e7778854be8a69a
https://doi.org/10.1007/978-1-4939-9089-4_1
https://doi.org/10.1007/978-1-4939-9089-4_1
Publikováno v:
PLoS ONE, Vol 15, Iss 7, p e0235929 (2020)
PLoS ONE
PLoS ONE
Combinations of three or more drugs are routinely used in various medical fields such as clinical oncology and infectious diseases to prevent resistance or to achieve synergistic therapeutic benefits. The very large number of possible high-order drug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5950e81d7f742f2e56ac2fd038204774
https://doi.org/10.1371/journal.pone.0235929
https://doi.org/10.1371/journal.pone.0235929
Publikováno v:
Journal of Visualized Experiments : JoVE
A synergistic drug combination has a higher efficacy compared to the effects of individual drugs. Checkerboard assays, where drugs are combined in many doses, allow sensitive measurement of drug interactions. However, these assays are costly and do n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61f5878562ce8870af029cf9e31d8d9f
https://pubmed.ncbi.nlm.nih.gov/29985330
https://pubmed.ncbi.nlm.nih.gov/29985330
Small interfering RNAs (siRNA) are short nucleic acid fragments of about 20-27 nucleotides, which can inhibit the expression of specific genes. siRNA based RNAi technology has emerged as a promising method for the treatment of a variety of diseases.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36ea8cdd41861e363e3769670ee86c9a
https://aperta.ulakbim.gov.tr/record/48699
https://aperta.ulakbim.gov.tr/record/48699
Autor:
Hilal Kazan, Kaan Yilancioglu, Nil Sahin, Melike Cokol-Cakmak, Sriram Chandrasekaran, Murat Cokol, James J. Collins
Publikováno v:
Molecular Systems Biology
European Molecular Biology Organization (EMBO)
European Molecular Biology Organization (EMBO)
Combination antibiotic therapies are being increasingly used in the clinic to enhance potency and counter drug resistance. However, the large search space of candidate drugs and dosage regimes makes the identification of effective combinations highly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f353c83a261b31f9e7203ffc6e8059b5
https://pubmed.ncbi.nlm.nih.gov/27222539
https://pubmed.ncbi.nlm.nih.gov/27222539
Autor:
Sriram Chandrasekaran, Melike Cokol‐Cakmak, Nil Sahin, Kaan Yilancioglu, Hilal Kazan, James J Collins, Murat Cokol
Publikováno v:
Molecular Systems Biology, Vol 12, Iss 5, Pp 1-12 (2016)
Abstract Combination antibiotic therapies are being increasingly used in the clinic to enhance potency and counter drug resistance. However, the large search space of candidate drugs and dosage regimes makes the identification of effective combinatio
Externí odkaz:
https://doaj.org/article/17f3a9120bf541f581b79c26f0a3f9d4