Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Melihat Fidan"'
Publikováno v:
Analytical Biochemistry. 306:212-221
A sensitive assay for quantitating DNA damage within individual genes would be a valuable tool for identifying the molecular mechanisms of disease and the sites of action of various carcinogens and anticancer drugs. This report describes a competitiv
Autor:
Jeanne M. Wehner, Barbara J. Bowers, Paulo Kofuji, Mark W. Nowak, Jim Boulter, Purnima Deshpande, Johannes Schwarz, Cesar Labarca, Wenmei Shi, Melihat Fidan, Sigrid Schwarz, Zhou-Feng Chen, Raad Nashmi, Hong Dang, Carlos Fonck, Henry A. Lester, Baljit S. Khakh
Publikováno v:
Proceedings of the National Academy of Sciences. 98:2786-2791
Knock-in mice were generated that harbored a leucine-to-serine mutation in the α4 nicotinic receptor near the gate in the channel pore. Mice with intact expression of this hypersensitive receptor display dominant neonatal lethality. These mice have
Autor:
Melihat Fidan, Naren L. Banik, Swapan K. Ray, Edward L. Hogan, Gloria G. Wilford, Mark W. Nowak
Publikováno v:
Brain Research. 852:326-334
Calpain, a Ca2+-dependent cysteine protease, has previously been implicated in apoptosis or programmed cell death (PCD) in immune cells. Although oxidative stress and intracellular free Ca2+ are involved in neurodegenerative diseases, the mechanism o
Autor:
Fredric R. Boockfor, Melihat Fidan
Publikováno v:
Methods (San Diego, Calif.). 33(4)
The reverse hemolytic plaque assay has been used for several years to study hormone release from various endocrine cell types. The basic method utilizes a monolayer (consisting of indicator erythrocytes and the cells under study) that is fixed to the
Autor:
Giovanna Bartolini, Vittorio Tomasi, Franca Guerrini, Mariella Chiricolo, Marina Orlandi, Melihat Fidan, Luisa Minghetti, Claudio Franceschi
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism. 876:486-493
It has previously been shown that platelet-free human monocytes, when properly incubated in the presence of animal and human sera, became capable of producing large amounts of thromboxane A 2 and prostaglandin E 2 . The characteristics of these proce