Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Melih O. Babaoglu"'
Publikováno v:
Cukurova Medical Journal, Vol 47, Iss 3, Pp 1015-1023 (2022)
Purpose: In this study, the possible effects of CYP2C9 polymorphisms on the clinical response to losartan were investigated in a group of hypertensive patients. Materials and Methods: Seventy-four patients, newly diagnosed to have essential hypertens
Externí odkaz:
https://doaj.org/article/80ad30cf17b34a588b83796ca80f079c
Autor:
Ahmet Muderrisoglu, Elif Babaoglu, Elif Tugce Korkmaz, Said Kalkisim, Erdem Karabulut, Salih Emri, Melih O. Babaoglu
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Objective: To investigate the effects of genetic polymorphisms of human nicotinic acetylcholine receptor subunits α3, α4 and α5, which are encoded by CHRNA3, CHRNA4 CHRNA5 genes, respectively, on nicotine addiction and outcomes of pharmacological
Externí odkaz:
https://doaj.org/article/f88a8c46a0db4226878ab68e4ddf15fd
Autor:
Ahmet Muderrisoglu, Elif Babaoglu, Elif Tugce Korkmaz, Mert C. Ongun, Erdem Karabulut, Alper B. Iskit, Salih Emri, Melih O. Babaoglu
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
ObjectivesTo determine the effects of genetic polymorphisms of ABCB1 (MDR1), CYP2A6, CYP2B6 on smoking status, and clinical outcomes of smoking cessation therapies in a Turkish population.Methods130 smokers and 130 non-smokers were recruited. Individ
Externí odkaz:
https://doaj.org/article/164ee0b6ce2e435e848997f954c1c7dc
Autor:
Mert C. Ongun, Nazan Vanli Tonyali, Ozan Kaplan, Ilter Deger, Mustafa Celebier, Nursabah E. Basci Akduman, Dilek Sahin, Aykan Yucel, Melih O. Babaoglu
Publikováno v:
Placenta. 137:88-95
Autor:
Yong-Soon Cho, Phuong Thi Thu Nguyen, Jong-Lyul Ghim, Jin Ah Jung, Eun Young Kim, Masud Parvez, Jae-Gook Shin, Melih O. Babaoglu, Said Kalkisim, Jeong-Kon Park
Publikováno v:
British Journal of Clinical Pharmacology. 88:1159-1169
Aim Tenofovir and para-aminosalicylic acid (PAS) may be co-prescribed to treat patients with concomitant infections of human immunodeficiency virus and Mycobacterium tuberculosis bacteria. Both drugs are known to have remarkable renal uptake transpor
Autor:
Maarten Bak, Selene R. T. Veerman, H. Tuppurainen, K. van Eijk, C. Morgenroth, M. Edlinger, S. Schreiter, S. Leucht, E. Jeger-Land, G. Yoca, I.M. Erdogan, Aygun Ertugrul, M. Lähteenvuo, Tero Hallikainen, J. Tiihonen, K.P. Grootens, A. Narang, Bochao Lin, W. Alink, S.E. Legge, M.Z. van der Horst, T. Görlitz, Yavuz Ayhan, Chad A. Bousman, A. Hasan, A.E. Anil Yağcıoğlu, D Cohen, Antonio F. Pardiñas, A. Müderrisoğlu, C. Pantelis, A. Bouhuis, S. Ripke, Eila Repo-Tiihonen, Ian P. Everall, J P A M Bogers, J. Schneider-Thoma, E. Beld, Cynthia Okhuijsen-Pfeifer, Melih O. Babaoglu, J.T.R. Walters, M. de Vos, M. de Koning, T. Oviedo-Salcedo, Jurjen J. Luykx, E. Wagner, H. van Beek, M. Veereschild, S. Gutwinski
Clozapine is the most effective antipsychotic for patients with treatment-resistant schizophrenia. However, response is highly variable and possible genetic underpinnings of this variability remain unknown. Here, we performed polygenic risk score (PR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28540b11031415a11170bb14f98d6f87
https://doi.org/10.1101/2021.06.06.21258200
https://doi.org/10.1101/2021.06.06.21258200
Autor:
Salih Emri, Mert C. Ongun, Elif Tugce Korkmaz, Erdem Karabulut, Alper B. Iskit, Melih O. Babaoglu, Elif Babaoglu, Ahmet Muderrisoglu
Publikováno v:
Frontiers in Genetics
Frontiers in Genetics, Vol 11 (2020)
Frontiers in Genetics, Vol 11 (2020)
ObjectivesTo determine the effects of genetic polymorphisms of ABCB1 (MDR1), CYP2A6, CYP2B6 on smoking status, and clinical outcomes of smoking cessation therapies in a Turkish population.Methods130 smokers and 130 non-smokers were recruited. Individ
Autor:
Berna B Kıvırcık Akdede, Alp Üçok, Kristel R. van Eijk, Evelien Van Assche, Edwin Beld, Dan Cohen, Yasemin Görgülü, Jelena Medic, Vesile Altınyazar, Erwin Bekema, Cynthia Okhuijsen-Pfeifer, Jurjen J. Luykx, Gökhan Yoca, Yavuz Ayhan, Jan P.A.M. Bogers, Memduha Aydin, Mustafa Çelik, A Elif Anıl Yağcıoğlu, Hasret Ozan, Fatma Özlem Orhan, Ayşen Esen Danacı, Bilge Çetin İlhan, Semra Ulusoy, Hatice Özdemir, İsmet Kaygısız, Haldun Soygür, Hanneke van Beek, Annemieke A M de Jonge, Köksal Alptekin, Ahmet Muderrisoglu, Lindy J G B Kool, Melih O. Babaoglu, Bochao D. Lin, Selene R. T. Veerman
Publikováno v:
Schizophrenia Bulletin Open. 1
Clozapine (CLZ) is considered the most effective antipsychotic, but its use is associated with neutropenia (CIN) and agranulocytosis (CIA). Although the exact etiology of these hazardous side effects is unknown, 4 genetic polymorphisms have been impl
Autor:
Cagatay Karaaslan, Nesrin Dilbaz, İbrahim Karakaya, Başaran Demir, Hayriye Akel Bilgic, Yavuz Ayhan, Şeref Can Gürel, Sevilay Karahan, Melih O. Babaoglu, Berna Uluğ
Publikováno v:
Turkish Journal of Psychiatry.
Objective Neuropeptide Y (NPY) is a protein widely expressed in the central nervous system and involved in diverse physiological processes, such as emotional regulation, nutritional behavior, and stress. In some populations, studies on alcohol depend
Autor:
Ragip Ozgur Karaca, Lokman Cevik, Mustafa Tugrul Goktas, Said Kalkisim, Levent Kilic, Ali Akdogan, Atilla Bozkurt, Umit Yasar, Melih O. Babaoglu, Leif Bertilsson
Publikováno v:
Basic & Clinical Pharmacology & Toxicology. 121:266-271
Behçet's disease (BD) is a systemic autoimmune disorder. Cytochrome P450 enzymes (CYPs) are responsible for various drug metabolism reactions as well as those of endogenous substances which may be associated with autoimmune disease susceptibility. R