Blockade of the Granzyme B/Perforin Pathway through Overexpression of the Serine Protease Inhibitor PI-9/SPI-6 Constitutes a Mechanism for Immune Escape by Tumors

Autor: Medema, J. P., de Jong, J., Peltenburg, L. T. C., Verdegaal, E. M. E., Gorter, A., Bres, S. A., Hahne, M., Albar, J. P., Melief, C. J. M., Offringa, R.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, 2001 Sep . 98(20), 11515-11520.

Externí odkaz: https://www.jstor.org/stable/3056746

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

The relationship between class I binding affinity and immunogenicity of potential cytotoxic T cell epitopes

Autor: Sette, A., Vitiello, A., Reherman, B., Fowler, P., Nayersina, R., Kast, W. M., Melief, C. J. M., Oseroff, C., Yuan, L., Ruppert, J., Sidney, J., Del Guercio, M. -F, Southwood, S., Kubo, R. T., Chesnut, R. W., Grey, H. M., Francis Chisari

Publikováno v: Scopus-Elsevier

The relationship between binding affinity for HLA class I molecules and immunogenicity of discrete peptide epitopes has been analyzed in two different experimental approaches. In the first approach, the immunogenicity of potential epitopes ranging in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::034c91a9e7d44fc5b616feb006a147d5
https://doi.org/10.4049/jimmunol.153.12.5586

Immunogenicity of Peptides Bound to MHC Class I Molecules Depends on the MHC-Peptide Complex Stability

Autor: Burg, S. H., Visseren, M. J. W., Brandt, R. M. P., W Martin Kast, Melief, C. J. M.

Publikováno v: Scopus-Elsevier
The Journal of Immunology, 3308-3314. The American Association of Immunologists
STARTPAGE=3308;ENDPAGE=3314;TITLE=The Journal of Immunology

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::523c9bd1c743b9237622f6afe3c81ace
https://hdl.handle.net/1887/8770

Regulatory effect of interleukin-4 (IL-4) on the expression and function of lymphocyte adhesion receptors involved in IL-2-induced cell aggregation

Autor: Vyth-Dreese, F. A., Kooyk, Y., Dellemijn, T. A. M., Melief, C. J. M., Carl Figdor

Publikováno v: Immunology, 78(2), 244-51. Wiley-Blackwell
Vyth-Dreese, F A, Van Kooyk, Y, Dellemijn, T A, Melief, C J & Figdor, C G 1993, ' Regulatory effect of interleukin-4 (IL-4) on the expression and function of lymphocyte adhesion receptors involved in IL-2-induced cell aggregation ', Immunology, vol. 78, no. 2, pp. 244-51 .
Scopus-Elsevier
Immunology, 78, 2, pp. 244-251
Immunology, 78, 244-251. Blackwell science ltd

Human recombinant interleukin-4 (rIL-4) was studied for its capacity to inhibit rIL-2-induced lymphoid cell aggregation. In contrast to rIL-2, rIL-4 was unable to induce cluster formation by itself. However, when added simultaneously with rIL-2 to cu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::7b97c5fa01f913fde434ecba7e0853c3
https://research.vumc.nl/en/publications/73b7f782-58e2-4296-b0cd-e5a432ece41b