CRISPR-Cas9 screening reveals a distinct class of MHC-I binders with precise HLA-peptide recognition

Autor: Tom A.W. Schoufour, Anneloes van der Plas - van Duijn, Ian Derksen, Marije Melgers, Jacqueline M.F. van Veenendaal, Claire Lensen, Mirjam H.M. Heemskerk, Jacques Neefjes, Ruud H.M. Wijdeven, Ferenc A. Scheeren

Publikováno v: iScience, Vol 27, Iss 6, Pp 110120- (2024)

Summary: Human leukocyte antigen (HLA) class-I molecules present fragments of the cellular proteome to the T cell receptor (TCR) of cytotoxic T cells to control infectious diseases and cancer. The large number of combinations of HLA class-I allotypes

Externí odkaz: https://doaj.org/article/4f8712afc8ef4d058388bf0791f5c4b4

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Glycosyl-phosphatidylinositols in protozoa structure, biosynthesis and intracellular localisation

Autor: Zinecker, C. F., Gerold, P., Azzouz, N., Boris Striepen, Schmidt, A., Berhe, S., Kimmel, J., Keddes, M. H., Blackman, M. J., Schofield, L., Ogun, S., Damm, J. B. L., Melgers, P. A. T., Koolen, M., Gerwig, G. J., Vliegenhardt, J. F. G., Dubremetz, J. F., Holder, A. A., Eckert, V., Capdeville, Y., Tachado, S. D., Schwarz, R. T.

Publikováno v: ResearcherID
Scopus-Elsevier

We are investigating the structure and biosynthesis of glycosyl-phosphatidylinositols (GPI) in the protozoa Toxoplasma gondii, Plasmodium falciparum, Plasmodium yoelii and Paramecium primaurelia. This comparison of structural and biosynthesis data sh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::4f2e66e765a8fa407bdaebeb461c8d1f
https://pubmed.ncbi.nlm.nih.gov/9343937

Abstracts of papers Pharmaceutical and biomedical analysis meeting

Autor: Both-Miedema, R., Jansen, E., Claessens, H., Hendriks, P., Ackermans, M., Sparidans, R., Everaerts, F., Groot, G., Koops, R., Wubs, K., Koops, R., Jong, J., Cheung, S., Maessen, P., Pinedo, H., Vijgh, W., Hartigh, J., Langebroek, R., Vermeij, P., Doom, L., Leeuwen, F., Heeremans, C., Hoeven, R., Niessen, W., Tjaden, U., Greef, J., Hempenius, J., Staal, B., Jeuring, H., Mensink, C., Jonkman, J., Hindriks, H., Maris, F., Pasters, A., Smet, M., Massart, D., Janssen, P., Hamelinck, R., Melgers, P., Nispen, J., Zeeland, M., Ven, M., Vink, J., Lambrechts, H., Pattyn, G., Oosterom, A., Bruijn, E., Leeuwenkamp, O., Barto, R., Greuter, H., Lips, P., Netelenbos, J., Maris, F., Vervoort, R., Vrieling, M., Reinerink, E., Berg, R., Roets, E., Aerden, L., Hoogmartens, I., Rose, S., Crombeen, J., Bueren, L., Rosing, H., Elferink, F., Vaart, F., Schoots, A., Vries, P., Verheggen, T., Steijger, O., Hoksbergen, E., Baumann, R., Holthuis, J., Brinkman, U., Takkenberg, B., Ingen, H., Ackermans, M., Endert, E., Tjaden, UR, Reeuwijk, HJEM, Greef, J., Pattyn, G., Oosterom, A., Bruijn, E., Water, C., Haagsma, N., Ham, W., Piersma, A., Ginkel, L., Stephany, R., Farla, J., Rossum, H., Gijn, R., Beijnen, J., Clippeleir, J., Horenblas, S., Underberg, W., Tellingen, O., Beilnen, J., Woude, H., Nooven, W., Twillert, K., Zeijlmans, P., Olling, M., Derks, H., Naidong, Weng, Cachet, Th., Hoogmartens, J., Wieling, J., Coencgracht, P., Doornbos, D., Windhorst, G.

Publikováno v: Pharmacy World & Science; February 1989, Vol. 11 Issue: Supplement 1 pN1-N12, 12p