Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Melford, John"'
Publikováno v:
PeerJ, Vol 7, p e6979 (2019)
A major benefit of expansive cancer genome projects is the discovery of new targets for drug treatment and development. To date, cancer driver genes have been primarily identified by methods based on gene mutation frequency. This approach fails to id
Externí odkaz:
https://doaj.org/article/b1fc5ba347e745929aaf926ff15668e1
Publikováno v:
Cancer Research. 82:P3-19
Background: Radiation therapy (RT) is frequently recommended for post-surgery treatment of early-stage breast cancer (BC) patients, though not all benefit. Clinical factors currently guide RT treatment decisions. This work presents a high-accuracy ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c79001632dfdb1ba9369ef1225aa4cf
https://doi.org/10.1158/1538-7445.sabcs21-p3-19-05
https://doi.org/10.1158/1538-7445.sabcs21-p3-19-05
Publikováno v:
Advances in Physiology Education
The COVID-19 pandemic and the resulting “lockdown” have forced many medical schools to shift from traditional “face-to-face” teaching methodologies and embrace full online delivery. Although lectures and tutorials are readily communicated by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b927e3b09c35867ea94764dc960b1af5
https://doi.org/10.1152/advan.00048.2021
https://doi.org/10.1152/advan.00048.2021
Publikováno v:
PeerJ, Vol 5, p e2568 (2017)
Bioinformaticians have implemented different strategies to distinguish cancer driver genes from passenger genes. One of the more recent advances uses a pathway-oriented approach. Methods that employ this strategy are highly dependent on the quality a
Externí odkaz:
https://doaj.org/article/4d3b6fb8bc5f46cc89f215d96df2b110
Autor:
Nicola J Weston-Bell, Will Tapper, Jane Gibson, Dean Bryant, Yurany Moreno, Melford John, Sarah Ennis, Hanneke C Kluin-Nelemans, Andrew R Collins, Surinder S Sahota
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0149162 (2016)
In classic Hairy cell leukaemia (HCLc), a single case has thus far been interrogated by whole exome sequencing (WES) in a treatment naive patient, in which BRAF V(600)E was identified as an acquired somatic mutation and confirmed as occurring near-un
Externí odkaz:
https://doaj.org/article/d914e813f99e407b83e44dd669a7a407
Background: The DREAM Challenge evaluated methods to identify molecular pathways facilitating the detection of multiple genes affecting critical interactions and processes. Dysregulation of pathways by well-known driver genes is often found in the de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7ff4dd6f31722499328f64606141d68
Publikováno v:
Molecular omics. 16(2)
The Cancer Genome Atlas has provided expression values of 18 015 genes for different cancer types. Studies on the classification of cancers by machine learning algorithms have used different data and methods, which makes it difficult to compare their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98fd969e52cebff317f1347f361ef65b
https://pubmed.ncbi.nlm.nih.gov/32095794
https://pubmed.ncbi.nlm.nih.gov/32095794
Publikováno v:
PeerJ
PeerJ, Vol 7, p e6979 (2019)
PeerJ, Vol 7, p e6979 (2019)
A major benefit of expansive cancer genome projects is the discovery of new targets for drug treatment and development. To date, cancer driver genes have been primarily identified by methods based on gene mutation frequency. This approach fails to id
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc33ebe18529d2f27050ea6541744517
http://europepmc.org/articles/PMC6598669
http://europepmc.org/articles/PMC6598669
Publikováno v:
Advances in Intelligent Systems and Computing ISBN: 9783030228705
Late diagnosis and high costs are key factors that negatively impact the care of cancer patients worldwide. Although the availability of biological markers for the diagnosis of cancer type is increasing, costs and reliability of tests currently prese
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa72d90facfeb6175569eb73725b715e
https://doi.org/10.1007/978-3-030-22871-2_65
https://doi.org/10.1007/978-3-030-22871-2_65
Publikováno v:
Gene Reports. 19:100647
Almost one million patients are diagnosed with some form of Lung cancer every year. It is one of the deadliest malignant tumours worldwide and early detection is known to significantly improve a patient's survival. There is a need for early diagnosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a8b1bed54b62036d857a2a53172a2f4f
https://doi.org/10.1016/j.genrep.2020.100647
https://doi.org/10.1016/j.genrep.2020.100647