Persistent complement dysregulation with signs of thromboinflammation in active Long Covid.

Autor: Cervia-Hasler C; Department of Immunology, University Hospital Zurich, University of Zurich, 8091 Zurich, Switzerland., Brüningk SC; Department of Biosystems Science and Engineering, ETH Zurich, 4058 Basel, Switzerland.; Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland., Hoch T; Department of Immunology, University Hospital Zurich, University of Zurich, 8091 Zurich, Switzerland., Fan B; Department of Biosystems Science and Engineering, ETH Zurich, 4058 Basel, Switzerland.; Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland., Muzio G; Department of Biosystems Science and Engineering, ETH Zurich, 4058 Basel, Switzerland.; Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland., Thompson RC; Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Mount Sinai Clinical Intelligence Center, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Ceglarek L; Department of Immunology, University Hospital Zurich, University of Zurich, 8091 Zurich, Switzerland., Meledin R; Department of Immunology, University Hospital Zurich, University of Zurich, 8091 Zurich, Switzerland., Westermann P; Precision Proteomics Center, Swiss Institute of Allergy and Asthma Research, University of Zurich, 7265 Davos, Switzerland., Emmenegger M; Institute of Neuropathology, University Hospital Zurich, University of Zurich, 8091 Zurich, Switzerland., Taeschler P; Department of Immunology, University Hospital Zurich, University of Zurich, 8091 Zurich, Switzerland., Zurbuchen Y; Department of Immunology, University Hospital Zurich, University of Zurich, 8091 Zurich, Switzerland., Pons M; Department of Immunology, University Hospital Zurich, University of Zurich, 8091 Zurich, Switzerland., Menges D; Epidemiology, Biostatistics and Prevention Institute, University of Zurich, 8001 Zurich, Switzerland., Ballouz T; Epidemiology, Biostatistics and Prevention Institute, University of Zurich, 8001 Zurich, Switzerland., Cervia-Hasler S; Department of Immunology, University Hospital Zurich, University of Zurich, 8091 Zurich, Switzerland., Adamo S; Department of Immunology, University Hospital Zurich, University of Zurich, 8091 Zurich, Switzerland., Merad M; Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Charney AW; Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Mount Sinai Clinical Intelligence Center, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Puhan M; Epidemiology, Biostatistics and Prevention Institute, University of Zurich, 8001 Zurich, Switzerland., Brodin P; Unit for Clinical Pediatrics, Department of Women's and Children's Health, Karolinska Institute, 17165 Solna, Sweden.; Department of Immunology and Inflammation, Imperial College London, London W12 0NN, UK., Nilsson J; Department of Immunology, University Hospital Zurich, University of Zurich, 8091 Zurich, Switzerland., Aguzzi A; Institute of Neuropathology, University Hospital Zurich, University of Zurich, 8091 Zurich, Switzerland., Raeber ME; Department of Immunology, University Hospital Zurich, University of Zurich, 8091 Zurich, Switzerland., Messner CB; Precision Proteomics Center, Swiss Institute of Allergy and Asthma Research, University of Zurich, 7265 Davos, Switzerland., Beckmann ND; Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Mount Sinai Clinical Intelligence Center, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Division of Data Driven and Digital Medicine (D3M), Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Borgwardt K; Department of Biosystems Science and Engineering, ETH Zurich, 4058 Basel, Switzerland.; Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland., Boyman O; Department of Immunology, University Hospital Zurich, University of Zurich, 8091 Zurich, Switzerland.; Faculty of Medicine and Faculty of Science, University of Zurich, 8006 Zurich, Switzerland.

Publikováno v: Science (New York, N.Y.) [Science] 2024 Jan 19; Vol. 383 (6680), pp. eadg7942. Date of Electronic Publication: 2024 Jan 19.

Complement System and Adhesion Molecule Skirmishes in Fabry Disease: Insights into Pathogenesis and Disease Mechanisms.

Autor: Magnusen, Albert Frank¹ (AUTHOR) albert.magnusen@cchmc.org, Pandey, Manoj Kumar^1,2 (AUTHOR) manoj.pandey@cchmc.org

Publikováno v: International Journal of Molecular Sciences. Nov2024, Vol. 25 Issue 22, p12252. 39p.

Insights into the Risk Factors and Outcomes of Post-COVID-19 Syndrome—Results from a Retrospective, Cross-Sectional Study in Romania.

Autor: Bejan, Ioana¹ (AUTHOR) ioana.bejan@rez.umfcd.ro, Popescu, Corneliu Petru^1,2 (AUTHOR) corneliu.popescu@umfcd.ro, Ruta, Simona Maria^1,3 (AUTHOR) simona.ruta@umfcd.ro

Publikováno v: Life (2075-1729). Nov2024, Vol. 14 Issue 11, p1519. 14p.

Proteomic Evidence for Amyloidogenic Cross-Seeding in Fibrinaloid Microclots.

Autor: Kell, Douglas B.^1,2,3 (AUTHOR) dbk@liv.ac.uk, Pretorius, Etheresia^1,3 (AUTHOR) dbk@liv.ac.uk

Publikováno v: International Journal of Molecular Sciences. Oct2024, Vol. 25 Issue 19, p10809. 45p.

Examining the role of phosphorylation of p19 ^INK4d in its stability and ubiquitination using chemical protein synthesis.

Autor: Msallam M; Schulich Faculty of Chemistry , Technion-Israel Institute of Technology , Technion City , Hailfa 32000 , Israel . Email: abrik@technion.ac.il., Sun H; Schulich Faculty of Chemistry , Technion-Israel Institute of Technology , Technion City , Hailfa 32000 , Israel . Email: abrik@technion.ac.il., Meledin R; Schulich Faculty of Chemistry , Technion-Israel Institute of Technology , Technion City , Hailfa 32000 , Israel . Email: abrik@technion.ac.il., Franz P; Schulich Faculty of Chemistry , Technion-Israel Institute of Technology , Technion City , Hailfa 32000 , Israel . Email: abrik@technion.ac.il., Brik A; Schulich Faculty of Chemistry , Technion-Israel Institute of Technology , Technion City , Hailfa 32000 , Israel . Email: abrik@technion.ac.il.

Publikováno v: Chemical science [Chem Sci] 2020 May 19; Vol. 11 (21), pp. 5526-5531. Date of Electronic Publication: 2020 May 19 (Print Publication: 2020).