Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Meleah Cameron"'
Autor:
Corey Speers, Reshma Jagsi, Lori J. Pierce, Shyam Nyati, Meilan Liu, Cassandra L. Ritter, Nicole Hirsh, Amanda Zhang, Dafydd G. Thomas, Eric Olsen, Meleah Cameron, Kari Wilder-Romans, Benjamin C. Chandler, Leah Moubadder, Andrea M. Pesch, Anna R. Michmerhuizen
Higher doses of olaparib are sufficient to inhibit PAR formation in BRCA1-mutant SUM-149 cells. At higher concentrations of olaparib (1μM), combination treatment of PARP1 inhibition and radiation decreases PAR in a comparable manner to lower doses o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::623d55d5dd22fc6feaa49169a3f1f0b6
https://doi.org/10.1158/1535-7163.22518895
https://doi.org/10.1158/1535-7163.22518895
Autor:
Corey Speers, Reshma Jagsi, Lori J. Pierce, Shyam Nyati, Meilan Liu, Cassandra L. Ritter, Nicole Hirsh, Amanda Zhang, Dafydd G. Thomas, Eric Olsen, Meleah Cameron, Kari Wilder-Romans, Benjamin C. Chandler, Leah Moubadder, Andrea M. Pesch, Anna R. Michmerhuizen
Ki67 and p16 levels are decreased in tumors from animals treated with radiation and combination PARP-inhibitor and radiation. SUM-190 xenograft tumors that were harvested from mice at the completion of the long-term in vivo study. Protein expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::057703d4bde74df38c00e6668f4ad8bf
https://doi.org/10.1158/1535-7163.22518892
https://doi.org/10.1158/1535-7163.22518892
Autor:
Corey Speers, Reshma Jagsi, Lori J. Pierce, Shyam Nyati, Meilan Liu, Cassandra L. Ritter, Nicole Hirsh, Amanda Zhang, Dafydd G. Thomas, Eric Olsen, Meleah Cameron, Kari Wilder-Romans, Benjamin C. Chandler, Leah Moubadder, Andrea M. Pesch, Anna R. Michmerhuizen
Total PARP1 levels do not change with treatment but PAR levels are decreased by PARPi. Total levels of PARP1 were assessed in tumors from mice treated with olaparib. Olaparib treatment did not affect PARP1 protein expression by IHC in olaparib-alone,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::824f34ca3b79b528a88bfc2ddafacc24
https://doi.org/10.1158/1535-7163.22518886
https://doi.org/10.1158/1535-7163.22518886
Autor:
Corey Speers, Reshma Jagsi, Lori J. Pierce, Shyam Nyati, Meilan Liu, Cassandra L. Ritter, Nicole Hirsh, Amanda Zhang, Dafydd G. Thomas, Eric Olsen, Meleah Cameron, Kari Wilder-Romans, Benjamin C. Chandler, Leah Moubadder, Andrea M. Pesch, Anna R. Michmerhuizen
Enhancement ratios and toxicity for IBC clonogenic survival assays. Average radiation enhancement ratio (rER) and toxicity values are shown for each treatment in SUM-190 (A), MDA-IBC-3 (B), and SUM-149 (C) cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84c8c1b479d5f50abc8f6cb482defd87
https://doi.org/10.1158/1535-7163.22518898.v1
https://doi.org/10.1158/1535-7163.22518898.v1
Autor:
Corey Speers, Reshma Jagsi, Lori J. Pierce, Shyam Nyati, Meilan Liu, Cassandra L. Ritter, Nicole Hirsh, Amanda Zhang, Dafydd G. Thomas, Eric Olsen, Meleah Cameron, Kari Wilder-Romans, Benjamin C. Chandler, Leah Moubadder, Andrea M. Pesch, Anna R. Michmerhuizen
Extended methods for immunohistochemistry. Antibodies used in immunohistochemistry experiments are listed with each of the corresponding dilutions, retrieval techniques, and positive controls.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dec1ab52d25aad68186ffb5ea9a1a23
https://doi.org/10.1158/1535-7163.22518883
https://doi.org/10.1158/1535-7163.22518883
Autor:
Corey Speers, Reshma Jagsi, Lori J. Pierce, Shyam Nyati, Meilan Liu, Cassandra L. Ritter, Nicole Hirsh, Amanda Zhang, Dafydd G. Thomas, Eric Olsen, Meleah Cameron, Kari Wilder-Romans, Benjamin C. Chandler, Leah Moubadder, Andrea M. Pesch, Anna R. Michmerhuizen
Sustained locoregional control of disease is a significant issue in patients with inflammatory breast cancer (IBC), with local control rates of 80% or less at 5 years. Given the unsatisfactory outcomes for these patients, there is a clear need for in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08ab813eb94ed0666f01ed7b66b76c82
https://doi.org/10.1158/1535-7163.c.6542167
https://doi.org/10.1158/1535-7163.c.6542167
Autor:
Cassandra L. Ritter, Kari Wilder-Romans, Amanda Zhang, Benjamin C. Chandler, Powel H. Brown, Dafydd G. Thomas, Corey Speers, Anna R. Michmerhuizen, Theodore S. Lawrence, Shyam Nyati, Arul M. Chinnaiyan, Lori J. Pierce, Andrea M. Pesch, Nicole Hirsh, Leah Moubadder, Meleah Cameron, Yashar S. Niknafs, Meilan Liu, Tanner Ward, Marlie Androsiglio, Eric Olsen, Sofia D. Merajver
Publikováno v:
The Journal of clinical investigation, vol 130, iss 2
J Clin Invest
J Clin Invest
Increased rates of locoregional recurrence are observed in patients with basal-like breast cancer (BC) despite the use of radiation therapy (RT); therefore, approaches that result in radiosensitization of basal-like BC are critically needed. Using pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9970a1b7fde6d58b372572c5e26dbf2f
https://escholarship.org/uc/item/0vz4w13c
https://escholarship.org/uc/item/0vz4w13c
Autor:
Sofia D. Merajver, Eric Olsen, Meleah Cameron, Nicole Hirsh, Cassandra L. Ritter, Powel H. Brown, Andrea M. Pesch, Leah Moubadder, Lori J. Pierce, Dafydd G. Thomas, Amanda Zhang, Anna R. Michmerhuizen, Marlie Androsiglio, Arul M. Chinnaiyan, Theodore Lawrence, Kari Wilder-Romans, Tanner Ward, Benjamin C. Chandler, Meilan Liu, Corey Speers, Shyam Nyati, Yashar S. Niknafs
Publikováno v:
Cancer Research. 80:6273-6273
Background: Basal-like breast cancer (BC) has the highest rates of local recurrence despite the use of radiation therapy. Therefore, approaches for radiosensitization are critically needed for patients with this subtype of BC. Methods: Four independe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6d55af61c3821bf13a813b09e6fecb3
https://doi.org/10.1158/1538-7445.am2020-6273
https://doi.org/10.1158/1538-7445.am2020-6273
Autor:
Lori J. Pierce, Arul M. Chinnaiyan, Eric Olsen, Meilan Liu, Shyam Nyati, Meleah Cameron, Corey Speers, Leah Moubadder, Cassandra L. Ritter, Marlie Androsiglio, B. Chandler
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 105:S165
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9fc77d0d7e4dda39f09e062df16cf2b6
https://doi.org/10.1016/j.ijrobp.2019.06.188
https://doi.org/10.1016/j.ijrobp.2019.06.188
Autor:
Reshma Jagsi, Lori J. Pierce, Meilan Liu, Nicole Hirsh, Meleah Cameron, Anna R. Michmerhuizen, Kari Wilder-Romans, Leah Moubadder, Corey Speers, Amanda Zhang, Andrea M. Pesch
Publikováno v:
Cancer Research. 79:3924-3924
Purpose: Sustained locoregional control of disease is a significant issue in patients with inflammatory breast cancer (IBC) with local control rates Methods: Pharmacologic PARP1 inhibitors, olaparib and veliparib, were used at various concentrations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13e8252ccdc277051709307cfa736001
https://doi.org/10.1158/1538-7445.am2019-3924
https://doi.org/10.1158/1538-7445.am2019-3924