Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Melba Marie Tejera"'
Autor:
Dominique Lisiero, Alexander Hoffmann, Melba Marie Tejera, M. Suresh, Zhang Cheng, Brandon Neldner, Shelly M. Wuerzberger-Davis, Jay W. Warrick, Shigeki Miyamoto
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950), vol 205, iss 6
J Immunol
J Immunol
Optimal CD8 T cell immunity is orchestrated by signaling events initiated by TCR recognition of peptide Ag in concert with signals from molecules such as CD28 and 4-1BB. The molecular mechanisms underlying the temporal and spatial signaling dynamics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::957ac66f42bfa326234b671aebb341e0
https://escholarship.org/uc/item/75743708
https://escholarship.org/uc/item/75743708
Publikováno v:
Critical Reviews in Immunology. 34:121-146
Immunologic memory is the adaptive immune system's powerful ability to remember a previous antigen encounter and react with accelerated vigor upon antigen re-exposure. It provides durable protection against reinfection with pathogens and is the found
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dc451000bd9601d98c8a2cb35b79a22
https://doi.org/10.1615/critrevimmunol.2014010373
https://doi.org/10.1615/critrevimmunol.2014010373
Autor:
Erin H. Plisch, Kwan Yong Choi, Anna Jatzek, Eui Ho Kim, M. Suresh, Melba Marie Tejera, Jeremy A. Sullivan
Publikováno v:
The Journal of Immunology. 188:4305-4314
During a T cell response, the effector CTL pool contains two cellular subsets: short-lived effector cells (SLECs), a majority of which are destined for apoptosis, and the memory precursor effector cells, which differentiate into memory cells. Underst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::885625e542647dfc91bb6c48585dd332
https://doi.org/10.4049/jimmunol.1103568
https://doi.org/10.4049/jimmunol.1103568
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 191(1)
During a T cell response, naive CD8 T cells differentiate into effector cells. Subsequently, a subset of effector cells termed memory precursor effector cells further differentiates into functionally mature memory CD8 T cells. The transcriptional net
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6922030ffb2ba96cf3d02880f1f0fc6
https://pubmed.ncbi.nlm.nih.gov/23733882
https://pubmed.ncbi.nlm.nih.gov/23733882
Publikováno v:
Immunology and cell biology. 91(2)
CD8 T cells exhibit dynamic alterations in proliferation and apoptosis during various phases of the CD8 T-cell response, but the mechanisms that regulate cellular proliferation from the standpoint of CD8 T-cell memory are not well defined. The cyclin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39f2ea5927dcd8783bb685d77381a2ab
https://pubmed.ncbi.nlm.nih.gov/23318658
https://pubmed.ncbi.nlm.nih.gov/23318658
Much is known about the differentiation of naive T cells into distinct lineages of effector cells, but the molecular mechanisms underlying the generation and maintenance of CD4 T cell memory are poorly characterized. Our studies ascribe a novel role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::092854d6482da43a1d0a3370bdffab96
https://europepmc.org/articles/PMC3504176/
https://europepmc.org/articles/PMC3504176/
Autor:
Melba Marie Tejera, Sarah S. Donatelli, Jun-Min Zhou, Danielle L. Gilvary, Xianghong Chen, Erika A
Publikováno v:
Cancer Research. 75:450-450
Innate and adaptive immunity plays a critical role in defense against cancer but can be undermined by the tumor microenvironment. To understand the underlying mechanism, we set out to analyze the molecular and cellular basis for natural killer (NK) a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9aa61f69de8cca33530d4886a78e5683
https://doi.org/10.1158/1538-7445.am2015-450
https://doi.org/10.1158/1538-7445.am2015-450
Autor:
Dominique Lisiero, Melba Marie Tejera, Shelly Davis, Brandon Neldner, Marulasiddappa Suresh, Shigeki Miyamoto
Publikováno v:
The Journal of Immunology. 194:133.3-133.3
Numerous cell types, including T cells, respond to inflammatory stimuli by engaging the NF-κB signaling pathway. Classical studies with knockout mouse models demonstrated that T cell receptor (TCR) triggering of NF-κB is crucial for T cell function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76d548b0596c89f5934cdf5fd5564a5a
https://doi.org/10.4049/jimmunol.194.supp.133.3
https://doi.org/10.4049/jimmunol.194.supp.133.3