Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Melanie Wu"'
Autor:
Elizabeth B Draganova, Hui Wang, Melanie Wu, Shiqing Liao, Amber Vu, Gonzalo L Gonzalez-Del Pino, Z Hong Zhou, Richard J Roller, Ekaterina E Heldwein
Publikováno v:
PLoS Pathogens, Vol 20, Iss 1, p e1011936 (2024)
Nuclear egress is an essential process in herpesvirus replication whereby nascent capsids translocate from the nucleus to the cytoplasm. This initial step of nuclear egress-budding at the inner nuclear membrane-is coordinated by the nuclear egress co
Externí odkaz:
https://doaj.org/article/4ec664c6fbd343e48c9bf997df69f327
Autor:
Anjana C. Karawita, Yuanyuan Cheng, Keng Yih Chew, Arjun Challagulla, Robert Kraus, Ralf C. Mueller, Marcus Z. W. Tong, Katina D. Hulme, Helle Bielefeldt-Ohmann, Lauren E. Steele, Melanie Wu, Julian Sng, Ellesandra Noye, Timothy J. Bruxner, Gough G. Au, Suzanne Lowther, Julie Blommaert, Alexander Suh, Alexander J. McCauley, Parwinder Kaur, Olga Dudchenko, Erez Aiden, Olivier Fedrigo, Giulio Formenti, Jacquelyn Mountcastle, William Chow, Fergal J. Martin, Denye N. Ogeh, Françoise Thiaud-Nissen, Kerstin Howe, Alan Tracey, Jacqueline Smith, Richard I. Kuo, Marilyn B. Renfree, Takashi Kimura, Yoshihiro Sakoda, Mathew McDougall, Hamish G. Spencer, Michael Pyne, Conny Tolf, Jonas Waldenström, Erich D. Jarvis, Michelle L. Baker, David W. Burt, Kirsty R. Short
Publikováno v:
Genome Biology, Vol 24, Iss 1, Pp 1-24 (2023)
Abstract Background The Australian black swan (Cygnus atratus) is an iconic species with contrasting plumage to that of the closely related northern hemisphere white swans. The relative geographic isolation of the black swan may have resulted in a li
Externí odkaz:
https://doaj.org/article/78ecfc98e26e450ea7815f3fe5cca8c8
Autor:
Yanshan Zhu, Keng Yih Chew, Melanie Wu, Anjana C Karawita, Georgina McCallum, Lauren E Steele, Ayaho Yamamoto, Larisa I Labzin, Tejasri Yarlagadda, Alexander A Khromykh, Xiaohui Wang, Julian D J Sng, Claudia J Stocks, Yao Xia, Tobias R Kollmann, David Martino, Merja Joensuu, Frédéric A Meunier, Giuseppe Balistreri, Helle Bielefeldt-Ohmann, Asha C Bowen, Anthony Kicic, Peter D Sly, Kirsten M Spann, Kirsty R Short
Publikováno v:
PLoS Biology, Vol 20, Iss 8, p e3001728 (2022)
Children typically experience more mild symptoms of Coronavirus Disease 2019 (COVID-19) when compared to adults. There is a strong body of evidence that children are also less susceptible to Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2
Externí odkaz:
https://doaj.org/article/a26c38131664476296b2cb3b91aefadf
Autor:
Jane E. Sinclair, Conor J. Bloxham, Han Chiu, Keng Yih Chew, Jake Russell, Yusuke Yoshikawa, Helle Bielefeldt-Ohmann, Lauren E. Steele, Katina D. Hulme, Nathalie AJ. Verzele, Ellesandra C. Noye, Melanie Wu, Melissa E. Reichelt, Walter G. Thomas, Linda A. Gallo, Meredith A. Redd, Kirsty R. Short
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
People with diabetes mellitus are susceptible to both cardiovascular disease and severe influenza A virus infection. We hypothesized that diabetes also increases risks of influenza-associated cardiac complications. A murine type 1 (streptozotocin-ind
Externí odkaz:
https://doaj.org/article/a5d94dcaed7a4b54a8b0874e68cd9768
Autor:
Haru Nomura, Melanie Wu, Jiangning Song, Andrew Hung, Shirley Tran, Hang TA, Fahima Akther, Yuao Wu, Matt Johansen, Keng Chew, Vinod Kumar, Trent Woodruff, Richard Clark, Johannes Koehbach, Bruno Lomonte, Carlos Rosado, Merlin Thomas, Marion Boudes, Cyril Reboul, Lachlan Rash, Linda Gallo, Sumia Essid, Dominika Elmlund, Stefan Miemczyk, Nicole Hansbro, Bernadette Saunders, Warwick Britton, Peter Sly, Ayaho Yamamoto, Julián Fernández, Peter Moyle, Kirsty Short, Philip Hansbro, Sanjaya Kuruppu, Ian Smith, Niwanthi Rajapakse
Angiotensin-converting enzyme 2 (ACE2) is protective in cardiovascular disease, lung injury and diabetes yet paradoxically underlies our susceptibility to SARs-CoV2 infection and the fatal heart and lung disease it can induce. Furthermore, diabetic p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d0e805bf93ac1e9f1ccd3dfb8d9a2030
https://doi.org/10.21203/rs.3.rs-2642181/v1
https://doi.org/10.21203/rs.3.rs-2642181/v1
Autor:
Zhen Wei Marcus Tong, Stephanie Gras, Linda A. Gallo, Melanie Wu, Corey Smith, Emma J. Grant, Kirsty R. Short, Helen L. Barrett
Publikováno v:
The Febs Journal
The COVID‐19 pandemic has highlighted the vulnerability of people with diabetes mellitus (DM) to respiratory viral infections. Despite the short history of COVID‐19, various studies have shown that patients with DM are more likely to have increas
Autor:
Yanshan Zhu, Keng Yih Chew, Melanie Wu, Anjana C. Karawita, Georgina McCallum, Lauren E Steele, Ayaho Yamamoto, Larisa L. Labzin, Tejasri Yarlagadda, Alexander A. Khromykh, Xiaohui Wang, Julian Sng, Claudia J. Stocks, Yao Xia, Tobias R. Kollmann, David Martino, Merja Joensuu, Frédéric A. Meunier, Giuseppe Balistreri, Helle Bielefeldt-Ohmann, Asha C. Bowen, Anthony Kicic, Peter D. Sly, Kirsten M. Spann, Kirsty R. Short
RationaleYoung children (typically those
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bde235c09adf95bcd951e1830c992950
https://doi.org/10.1101/2021.03.08.434300
https://doi.org/10.1101/2021.03.08.434300
Publikováno v:
Movement disorders clinical practice, vol 7, iss 8
Mov Disord Clin Pract
Mov Disord Clin Pract
Author(s): Wu, Melanie; Ceponiene, Rita; Bayram, Ece; Litvan, Irene | Abstract: BackgroundNiemann-Pick disease type C (NPC) is a rare, autosomal recessive lysosomal lipid storage disorder. It may present with cerebellar ataxia, vertical supranuclear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db8fcb061bfc0e1886c3ce8606b9e4d3
https://escholarship.org/uc/item/1b7452qt
https://escholarship.org/uc/item/1b7452qt
Autor:
Thomas Hoffmann, Alexandra Hörmann, Maja Corcokovic, Jakub Zmajkovic, Matthias Hinterndorfer, Jasko Salkanovic, Fiona Spreitzer, Anna Köferle, Katrin Gitschtaler, Alexandra Popa, Sarah Oberndorfer, Florian Andersch, Markus Schaefer, Michaela Fellner, Nicole Budano, Jan G Ruppert, Paolo Chetta, Melanie Wurm, Johannes Zuber, Ralph A Neumüller
Publikováno v:
eLife, Vol 12 (2023)
Loss-of-function genetic tools are widely applied for validating therapeutic targets, but their utility remains limited by incomplete on- and uncontrolled off-target effects. We describe artificial RNA interference (ARTi) based on synthetic, ultra-po
Externí odkaz:
https://doaj.org/article/5be3978b927a49d695b800fdcd6cb2bb
Autor:
Christiane Kofink, Nicole Trainor, Barbara Mair, Simon Wöhrle, Melanie Wurm, Nikolai Mischerikow, Michael J. Roy, Gerd Bader, Peter Greb, Géraldine Garavel, Emelyne Diers, Ross McLennan, Claire Whitworth, Vesna Vetma, Klaus Rumpel, Maximilian Scharnweber, Julian E. Fuchs, Thomas Gerstberger, Yunhai Cui, Gabriela Gremel, Paolo Chetta, Stefan Hopf, Nicole Budano, Joerg Rinnenthal, Gerhard Gmaschitz, Moriz Mayer, Manfred Koegl, Alessio Ciulli, Harald Weinstabl, William Farnaby
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Protein degraders are an emerging drug modality; however, their properties lie beyond typical drug-like space. Here the authors report optimisation via structure-based exit vector and linker design towards the VHL-recruiting PROTAC ACBI2, an orally b
Externí odkaz:
https://doaj.org/article/3f90550853c6402d8f154d10f8e2a18c