Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Melanie Winkle"'
Autor:
Mihnea P. Dragomir, Enrique Fuentes-Mattei, Melanie Winkle, Keishi Okubo, Recep Bayraktar, Erik Knutsen, Aiham Qdaisat, Meng Chen, Yongfeng Li, Masayoshi Shimizu, Lan Pang, Kevin Liu, Xiuping Liu, Simone Anfossi, Huanyu Zhang, Ines Koch, Anh M. Tran, Swati Mohapatra, Anh Ton, Mecit Kaplan, Matthew W. Anderson, Spencer J. Rothfuss, Robert Silasi, Ravi S. Keshari, Manuela Ferracin, Cristina Ivan, Cristian Rodriguez-Aguayo, Gabriel Lopez-Berestein, Constantin Georgescu, Pinaki P. Banerjee, Rafet Basar, Ziyi Li, David Horst, Catalin Vasilescu, Maria Teresa S. Bertilaccio, Katayoun Rezvani, Florea Lupu, Sai-Ching Yeung, George A. Calin
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 14 (2023)
Sepsis remains a leading cause of death for humans and currently has no pathogenesis-specific therapy. Hampered progress is partly due to a lack of insight into deep mechanistic processes. In the past decade, deciphering the functions of small noncod
Externí odkaz:
https://doaj.org/article/d4033ceefb364ffba4d3f09a718cc569
Autor:
Jingshu Chen, Shu Tang, Sui Ke, James J. Cai, Daniel Osorio, Andrei Golovko, Benjamin Morpurgo, Shaodong Guo, Yuxiang Sun, Melanie Winkle, George A. Calin, Yanan Tian
Publikováno v:
Redox Biology, Vol 54, Iss , Pp 102377- (2022)
The metastasis-associated lung adenocarcinoma transcript1 (MALAT1) is a long noncoding RNA (lncRNA) and is known for its role in cancer development and prognosis. In this study, we report that MALAT1 plays an important role in regulating acute inflam
Externí odkaz:
https://doaj.org/article/34ce029492de4ce592dd5e9326126f50
Autor:
Lotteke J. Y. M. Swier, Agnieszka Dzikiewicz‐Krawczyk, Melanie Winkle, Anke van denBerg, Joost Kluiver
Publikováno v:
Molecular Oncology, Vol 13, Iss 1, Pp 26-45 (2019)
Myelocytomatosis viral oncogene homolog (MYC) plays an important role in the regulation of many cellular processes, and its expression is tightly regulated at the level of transcription, translation, protein stability, and activity. Despite this tigh
Externí odkaz:
https://doaj.org/article/f08e2f3d5e5f424d81fd892a336ab3e6
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 384:10-19
Chromosomal instability (CIN) is characterized by an increased frequency of changes in chromosome structure or number and is regarded as a hallmark of cancer. CIN plays a prevalent role in tumorigenesis and cancer progression by assisting the cancer
Autor:
Gerben Duns, Melanie Winkle, Lauren Chong, Daisuke Ennishi, Ryan D. Morin, Arjan Diepstra, David W. Scott, Joost L. Kluiver, Christian Steidl, Anke van den Berg
Publikováno v:
British Journal of Haematology.
Autor:
Melanie Winkle, Mina M Tayari, Klaas Kok, Gerben Duns, Natalia Grot, Marta Kazimierska, Annika Seitz, Debora de Jong, Jasper Koerts, Arjan Diepstra, Agnieszka Dzikiewicz-Krawczyk, Christian Steidl, Joost Kluiver, Anke van den Berg
Publikováno v:
Human Molecular Genetics, 31(24), 4193-4206. Oxford University Press
Long non-coding RNAs (lncRNAs) are involved in many normal and oncogenic pathways through a diverse repertoire of transcriptional and posttranscriptional regulatory mechanisms. LncRNAs that are under tight regulation of well-known oncogenic transcrip
Autor:
Agnieszka Dzikiewicz-Krawczyk, Lotteke J Y M Swier, Anke van den Berg, Melanie Winkle, Joost Kluiver
Publikováno v:
Molecular Oncology, Vol 13, Iss 1, Pp 26-45 (2019)
Molecular Oncology
Molecular Oncology
Myelocytomatosis viral oncogene homolog (MYC) plays an important role in the regulation of many cellular processes, and its expression is tightly regulated at the level of transcription, translation, protein stability, and activity. Despite this tigh
Publikováno v:
Nature Reviews. Drug Discovery
Therapeutic targeting of noncoding RNAs (ncRNAs), such as microRNAs (miRNAs) and long noncoding RNAs (lncRNAs), represents an attractive approach for the treatment of cancers, as well as many other diseases. Over the past decade, substantial effort h
Autor:
Debora de Jong, Laura Wijenberg, Klaas Kok, Agnieszka Dzikiewicz-Krawczyk, Izabella Slezak-Prochazka, Anke van den Berg, Bea Rutgers, Melanie Winkle, Jasper A. Koerts, Fubiao Niu, Margot Fernandez Hernandez, Tineke van der Sluis, M. M. Terpstra, Wierd Kooistra, Joost Kluiver
Publikováno v:
Cancers, Vol 12, Iss 3546, p 3546 (2020)
Cancers
Volume 12
Issue 12
Cancers, 12(12):3546, 1-18. MDPI AG
Cancers
Volume 12
Issue 12
Cancers, 12(12):3546, 1-18. MDPI AG
Simple SummaryMicroRNAs (miRNAs) are small RNAs that regulate expression of specific target genes. We observed elevated levels of miR-378a-3p in Burkitt lymphoma (BL) and studied its role in the pathogenesis of BL. Inhibition of miR-378a-3p reduced g
Publikováno v:
Molecular Biology of Long Non-coding RNAs
Molecular Biology of Long Non-coding RNAs ISBN: 9783030170851
Molecular Biology of Long Non-coding RNAs ISBN: 9783030170851
The development of lymphoid cells (i.e. B and T cells) is a complicated process involving various differentiation substages in bone marrow, thymus, lymph nodes and the circulation. Long noncoding (lnc)RNAs are in many ways involved in both normal lym