Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Melanie Vincent"'
Autor:
Afshin Dowlati, Andrea Bullock, Susanna Ulahannan, Manish Patel, Shubham Pant, Marsha Crochiere, Jian Chen, Devalingam Mahalingam, Mary Mulcahy, Lou Vaickus, Suming Wang, Melanie Vincent, Michael Cieslewicz, Jing Watnick, Dejan Juric, Susanne Fyfe, Randolph Watnick
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/c917f69f84ea4a2c8f0fd765dfdecead
Autor:
Afshin Dowlati, Andrea Bullock, Susanna Ulahannan, Manish Patel, Shubham Pant, Amita Patnaik, Marsha Crochiere, Devalingam Mahalingam, Wael Harb, Haider Mahdi, Manmeet Ahluwalia, Patrick Wen, Mary Mulcahy, Robert Guttendorf, Lou Vaickus, Suming Wang, Melanie Vincent, Michael Cieslewicz, Jing Watnick
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/cb08f1662e234a00860253c618292b87
Autor:
Melanie Vincent, Naomi L Sayre, Mark J Graham, Rosanne M Crooke, David J Shealy, Laura Liscum
Publikováno v:
PLoS ONE, Vol 5, Iss 9, p e12941 (2010)
Niemann-Pick type C (NPC) disease is a lysosomal storage disease characterized by the accumulation of cholesterol and glycosphingolipids. The majority of NPC patients die in their teen years due to progressive neurodegeneration; however, half of NPC
Externí odkaz:
https://doaj.org/article/5a268db0d5ab4baea643bd72f55fdf0a
Autor:
Jian Chen, Melanie Vincent, Wendy Li, Susanne Fyfe, Suming Wang, Victor Zota, James Mahoney, Randolph Watnick, Michael Cieslewicz, Jing Watnick
VT1021 is a first-in-class therapeutic agent which has been tested in a phase I/II clinical study in solid tumors (NCT03364400) and has advanced to a phase II/III clinical study in glioblastoma (NCT03970447). Preclinical studies demonstrated that VT1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f9bfed8941cf9c23bc3edb6ccdb23ec
https://doi.org/10.21203/rs.3.rs-2556883/v1
https://doi.org/10.21203/rs.3.rs-2556883/v1
Autor:
Simai Deng, Suming Wang, Randolph S. Watnick, Michael Cieslewicz, Susanne Fyfe, Jing Watnick, Jian Chen, Melanie Vincent, Marsha Crochiere, Wendy Li
Publikováno v:
Journal for ImmunoTherapy of Cancer. 9:A405-A406
BackgroundVT1021 is a first-in-class therapeutic agent in Phase I clinical studies in solid tumors. In vivo preclinical studies demonstrated that VT1021 inhibited tumor growth via stimulation of p53 and Thrombospondin-1 (Tsp-1) in MDSCs. Moreover, in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59c9a61afa60f88ec4d63baf51001599
https://doi.org/10.1136/jitc-2021-sitc2021.375
https://doi.org/10.1136/jitc-2021-sitc2021.375
Autor:
Mary F. Mulcahy, Wael Harb, Amita Patnaik, Manmeet Ahluwalia, Suming Wang, Robert Guttendorf, Andrea Bullock, Patrick Y. Wen, Melanie Vincent, Lou Vaickus, Shubham Pant, Haider Mahdi, Jing Watnick, Manish Patel, Afshin Dowlati, Michael Cieslewicz, Marsha Crochiere, Devalingam Mahalingam, Susanna Varkey Ulahannan
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Background VT1021, a cyclic pentapeptide, reprograms myeloid-derived suppressor cells (MDSCs) and induces the production of thrombospondin-1 (Tsp-1) in the tumor microenvironment (TME). Tsp-1, via binding to CD36 and CD47, induces apoptosis in tumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0895086c40d9545d75ef962e32cd1c4f
https://doaj.org/article/cb08f1662e234a00860253c618292b87
https://doaj.org/article/cb08f1662e234a00860253c618292b87
Autor:
Jian Chen, Manish R. Patel, Lou Vaickus, Jing Watnick, Melanie Vincent, Suming Wang, Devalingam Mahalingam, Afshin Dowlati, Randolph S. Watnick, Susanna Varkey Ulahannan, Shubham Pant, Susanne Fyfe, Michael Cieslewicz, Dejan Juric, Andrea Bullock, Mary F. Mulcahy, Marsha Crochiere
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
BackgroundOne barrier to treating pancreatic cancer is the immunosuppressive tumor microenvironment (TME). VT1021 is a cyclic peptide derived from prosaposin and stimulates thrombospondin-1 (Tsp-1) production in myeloid derived suppressor cells. Tsp-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e01e023e285901889b6b1ce13ff4de16
https://doi.org/10.1136/jitc-2021-sitc2021.369
https://doi.org/10.1136/jitc-2021-sitc2021.369
Autor:
Melanie Vincent, Jini L. Roby
Publikováno v:
Social work. 62(3)
Domestic minor sex trafficking (DMST) is a rapidly growing problem in the United States, yet legislative efforts to address victim needs have begun only recently. DMST is an issue that spans several areas of social work practice, as emerging research
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8413831a47bde5ae34efd2e598763037
https://pubmed.ncbi.nlm.nih.gov/28486669
https://pubmed.ncbi.nlm.nih.gov/28486669
Autor:
Melanie Vincent
Publikováno v:
Journal of the Royal Society for the Promotion of Health. 124:50-50
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::930eea06e44f0fc3591b15c89b05e914
https://doi.org/10.1177/146642400412400201
https://doi.org/10.1177/146642400412400201