Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Melanie Ufkin"'
Autor:
Jan Walewski, Tae Min Kim, Seok-Goo Cho, Isidro Jarque, Elżbieta Iskierka-Jażdżewska, Michelle Poon, H. Miles Prince, Sung Yong Oh, Francesca Lim, Cecilia Carmen Carpio Segura, Tran-Der Tan, Sabarish Ayyappan, Antonio Gutiérrez, Jingjin LI, Melanie Ufkin, Min Zhu, Aafia Chaudhry, Hesham Mohamed, Srikanth Ambati, Won-Seog Kim
Publikováno v:
HemaSphere, Vol 7, p e50570ac (2023)
Externí odkaz:
https://doaj.org/article/00b89dc771ce4ea588a693a6fbdd07ea
Autor:
Seok-Goo Cho, Tae Min Kim, Michał Taszner, Tsai Yun Chen, Aafia Chaudhry, Melanie Ufkin, Amulya Uppala, Ayesha Sabir, Hesham Mohamed, Srikanth Ambati, Emmanuel Bachy
Publikováno v:
HemaSphere, Vol 7, p e4155242 (2023)
Externí odkaz:
https://doaj.org/article/3747176128c044d5b57f29b8b8cf7ed5
Autor:
Silvana Novelli, Ashish Risal, Manjusha Namuduri, Jingxian Cai, Melanie Ufkin, Min Zhu, Sushmita Mukherjee, Jurriaan Brouwer-Visser, Aafia Chaudhry, Hesham Mohamed, Srikanth Ambati, Elżbieta Iskierka-Jażdżewska
Publikováno v:
HemaSphere, Vol 7, p e384923b (2023)
Externí odkaz:
https://doaj.org/article/90dbad0be6a74611b66184240348464d
Autor:
Rajat Bannerji, Jon E Arnason, Ranjana H Advani, Jennifer R Brown, John N Allan, Stephen M Ansell, Jeffrey A Barnes, Susan M O'Brien, Julio C Chávez, Johannes Duell, Andreas Rosenwald, Jennifer L Crombie, Melanie Ufkin, Jingjin Li, Min Zhu, Srikanth R Ambati, Aafia Chaudhry, Israel Lowy, Max S Topp
Publikováno v:
The Lancet Haematology. 9:e327-e339
Odronextamab is a hinge-stabilised, fully human IgG4-based CD20 × CD3 bispecific antibody that binds CD3 on T cells and CD20 on B cells. We aimed to evaluate the safety and antitumour activity of odronextamab in patients with relapsed or refractory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67c7cea0a7b2e4936015a8f286ba40f6
https://doi.org/10.1016/s2352-3026(22)00072-2
https://doi.org/10.1016/s2352-3026(22)00072-2
Autor:
Min Zhu, Jurriaan Brouwer-Visser, Srikanth R. Ambati, Hesham Mohamed, Vladimir Jankovic, Fang Wang, Hong Yan, Jingxian Cai, Carolina Leite De Oliveira, Melanie Ufkin, John D. Davis, Aafia Chaudhry, Masood Khaksar Toroghi
Publikováno v:
Blood. 140:11560-11561
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16fd5d102a0fb6f23f2053a878f073f8
https://doi.org/10.1182/blood-2022-158415
https://doi.org/10.1182/blood-2022-158415
Autor:
Won-Seog Kim, Tae Min Kim, Seok-Goo Cho, Isidro Jarque, Elżbieta Iskierka-Jażdżewska, Michelle Limei Poon, H. Miles Prince, Sung Yong Oh, Francesca Lim, Cecilia Carpio, Tran-Der Tan, Sabarish Ayyappan, Antonio Gutierrez, Jingjin Li, Melanie Ufkin, Min Zhu, Aafia Chaudhry, Hesham Mohamed, Srikanth R. Ambati, Jan Walewski
Publikováno v:
Blood. 140:1070-1071
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::453e66aa597a2b346769e3c8ad6d7ebf
https://doi.org/10.1182/blood-2022-158406
https://doi.org/10.1182/blood-2022-158406
Autor:
George D. Yancopoulos, David Sternberg, Gavin Thurston, S. M. Ansell, Julio C. Chavez, Israel Lowy, R. Advani, Johannes Duell, Susan O'Brien, Melanie Ufkin, Nathalie Fiaschi, Min Zhu, Jingjin Li, Vladimir Jankovic, Sara Hamon, Peter Gasparini, Robert Charnas, Jon E. Arnason, Srikanth R. Ambati, Jennifer R. Brown, Rajat Bannerji, Wen Zhang, Max S. Topp, Lieve Adriaens, A.J. Murphy, Andreas Rosenwald, John N. Allan
Publikováno v:
Hematological Oncology. 37:90-92
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b1fc175d62755662cc47189d6f3b6a3
https://doi.org/10.1002/hon.58_2629
https://doi.org/10.1002/hon.58_2629
Autor:
Seok-Goo Cho, Ayesha Sabir, Melanie Ufkin, Michał Taszner, Jurriaan Brouwer-Visser, Vladimir Jankovic, Mary-Margaret Keating, Steven Le Gouill, L. Andres Sirulnik, Cecilia Carpio, Tae Min Kim, Kim Won Seog, Min Zhu, Aafia Chaudhry, Siyang Leng, Miles Prince, Arancha Alonso, Srikanth R. Ambati, Don A. Stevens, Lieve Adriaens, Jingjin Li, Francesca Lorraine Wei Inng Lim, Michelle Poon
Publikováno v:
Blood. 136:28-29
BACKGROUND: Relapsed/refractory (R/R) B-cell non-Hodgkin lymphoma (B-NHL) remains an area of high unmet patient need and no curative options are currently available. Odronextamab (REGN1979) is a first-in-class, hinge-stabilized, fully human IgG4-base
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8da4338ed227b86e781ebc3c8db5669a
https://doi.org/10.1182/blood-2020-136344
https://doi.org/10.1182/blood-2020-136344
Autor:
Peter Gasparini, Jennifer R. Brown, Sara Hamon, Wen Zhang, Robin Joyce, Jeffrey A. Barnes, Ranjana H. Advani, Jon E. Arnason, Stephen M. Ansell, Lieve Adriaens, Vladimir Jankovic, Susan O'Brien, Raquel Deering, Johannes Duell, Srikanth R. Ambati, Kevin A. David, Max S. Topp, George D. Yancopoulos, Andrew J. Murphy, Julio C. Chavez, Jingjin Li, David Sternberg, Israel Lowy, Anfal Ibrahim, Rajat Bannerji, John N. Allan, Min Zhu, Peter Martin, Gavin Thurston, Nathalie Fiaschi, Melanie Ufkin, David M. Weinreich, Robert Charnas, Olulanu H Aina
Publikováno v:
Blood. 134:762-762
Background REGN1979 is an anti-CD20 x anti-CD3 bispecific IgG4 antibody (Ab) modified to reduce Fc binding. Engaging both targets results in CD20-specific, local T-cell activation and cytotoxicity, a mechanism of action distinct from standard anti-CD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b0e83d9c32f9f8c15520aa0b4e81aa7
https://doi.org/10.1182/blood-2019-122451
https://doi.org/10.1182/blood-2019-122451
Autor:
Jingjin Li, Johannes Duell, Sara Hamon, Ranjana H. Advani, Julio C. Chavez, Israel Lowy, Jeffrey A. Barnes, Nathalie Fiaschi, Stephen M. Ansell, Susan O'Brien, Robert Charnas, Vladimir Jankovic, David Sternberg, Xiaoyu Yan, Melanie Ufkin, Gavin Thurston, Srikanth R. Ambati, Max S. Topp, Jennifer R. Brown, Jon E. Arnason, Wen Zhang, Rajat Bannerji, Lieve Adriaens, John N. Allan, Peter Gasparini, Mark Navarro
Publikováno v:
Blood. 132:1690-1690
Introduction REGN1979 is an anti-CD20 x anti-CD3 bispecific IgG4 antibody (Ab) modified to reduce Fc binding. Engaging both targets results in CD20-specific, local T-cell activation and cytotoxicity, a mechanism of action distinct from standard anti-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6daba481c46c39aba06dcbcc7a1efdd0
https://doi.org/10.1182/blood-2018-99-113328
https://doi.org/10.1182/blood-2018-99-113328