Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Melanie Trobe"'
Autor:
Jonathan W. Lehmann, Ian T. Crouch, Daniel J. Blair, Melanie Trobe, Pulin Wang, Junqi Li, Martin D. Burke
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
Despite the progress in C(sp3) cross-coupling reactions, full control over the stereochemistry remains a challenge. Here, the authors show that phosphine-containing axially shielded Pd(II) complexes enable Suzuki-Miyaura cross-couplings of unactivate
Externí odkaz:
https://doaj.org/article/8dd4c2e0a80b4f308053aec58a157f12
Autor:
Daniel J. Blair, Sriyankari Chitti, Melanie Trobe, David M. Kostyra, Hannah M. S. Haley, Richard L. Hansen, Steve G. Ballmer, Toby J. Woods, Wesley Wang, Vikram Mubayi, Michael J. Schmidt, Robert W. Pipal, Greg. F. Morehouse, Andrea M. E. Palazzolo Ray, Danielle L. Gray, Adrian L. Gill, Martin D. Burke
Publikováno v:
Nature. 604:92-97
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3778c97d6e48bb9d2099abe1abd020c
https://doi.org/10.1038/s41586-022-04491-w
https://doi.org/10.1038/s41586-022-04491-w
Autor:
Melanie Trobe, Till Schreiner, Martin Vareka, Sebastian Grimm, Bernhard Wölfl, Rolf Breinbauer
Publikováno v:
European Journal of Organic Chemistry. 2022
Teraryl-based α-helix mimetics have proven to be useful compounds for the inhibition of protein-protein interactions (PPI). We have developed a modular and flexible approach for the synthesis of teraryl-based α-helix mimetics using pyridine contain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06f4be782c1635007092d1aa42b63677
https://doi.org/10.1002/ejoc.202101280
https://doi.org/10.1002/ejoc.202101280
Autor:
Melanie Trobe, Martin Vareka, Till Schreiner, Patrick Dobrounig, Carina Doler, Ella B. Holzinger, Andreas Steinegger, Rolf Breinbauer
Publikováno v:
European Journal of Organic Chemistry. 2022
Teraryl-based α-helix mimetics have proven to be useful compounds for the inhibition of protein-protein interactions (PPI). We have developed a modular and flexible approach for the synthesis of teraryl-based α-helix mimetics using a benzene core u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af616f7feb0922dc2501c068359b60b8
https://doi.org/10.1002/ejoc.202101278
https://doi.org/10.1002/ejoc.202101278
Publikováno v:
European journal of organic chemistry. 2022(17)
Teraryl-based α-helix mimetics have proven to be useful compounds for the inhibition of protein-protein interactions (PPI). We have developed a modular and flexible approach for the synthesis of teraryl-based α-helix mimetics using a benzene core u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4395ca0e0d957e690c5b51c9b28cfdc6
https://pubmed.ncbi.nlm.nih.gov/35910460
https://pubmed.ncbi.nlm.nih.gov/35910460
Autor:
Daniel J, Blair, Sriyankari, Chitti, Melanie, Trobe, David M, Kostyra, Hannah M S, Haley, Richard L, Hansen, Steve G, Ballmer, Toby J, Woods, Wesley, Wang, Vikram, Mubayi, Michael J, Schmidt, Robert W, Pipal, Greg F, Morehouse, Andrea M E, Palazzolo Ray, Danielle L, Gray, Adrian L, Gill, Martin D, Burke
Publikováno v:
Nature. 604(7904)
Fully automated synthetic chemistry would substantially change the field by providing broad on-demand access to small molecules. However, the reactions that can be run autonomously are still limited. Automating the stereospecific assembly of Csp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ce70362725261bad934b1b7864de8366
https://pubmed.ncbi.nlm.nih.gov/35134814
https://pubmed.ncbi.nlm.nih.gov/35134814
Autor:
Breinbauer, Martin Vareka, Benedikt Dahms, Mario Lang, Minh Hao Hoang, Melanie Trobe, Hansjörg Weber, Maximilian M. Hielscher, Siegfried R. Waldvogel, Rolf
Publikováno v:
Catalysts; Volume 10; Issue 3; Pages: 340
Teraryl-based alpha-helix mimetics have resulted in efficient inhibitors of protein-protein interactions (PPIs). Extending the concept to even longer oligoarene systems would allow for the mimicking of even larger interaction sites. We present a high
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::6c8d6be030e44de21142fb7d4b4769df
Autor:
Martin Vareka, Benedikt Dahms, Mario Lang, Minh Hao Hoang, Melanie Trobe, Hansjörg Weber, Maximilian M. Hielscher, Siegfried R. Waldvogel, Rolf Breinbauer
Publikováno v:
Catalysts, Vol 10, Iss 3, p 340 (2020)
Teraryl-based alpha-helix mimetics have resulted in efficient inhibitors of protein-protein interactions (PPIs). Extending the concept to even longer oligoarene systems would allow for the mimicking of even larger interaction sites. We present a high
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doajarticles::3b8963d96b07fa4d78749b9cac0da312
https://www.mdpi.com/2073-4344/10/3/340
https://www.mdpi.com/2073-4344/10/3/340
Autor:
Melanie Trobe, Martin D. Burke
Publikováno v:
Angewandte Chemie. 130:4266-4288
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1bfac04d45e152ab5e471ab57c277a3a
https://doi.org/10.1002/ange.201710482
https://doi.org/10.1002/ange.201710482
Publikováno v:
Monatshefte Fur Chemie
Sequential and iterative Pd-catalyzed cross-coupling reactions can be performed in which the order of C–C bond formations can be controlled either by the attenuated leaving groups of the multireactive substrate or by specific catalyst/ligand combin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f263e3f21bc9a24635979c83163a759d
https://doi.org/10.1007/s00706-016-1883-7
https://doi.org/10.1007/s00706-016-1883-7