Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Melanie Tran"'
Publikováno v:
Molecular Metabolism, Vol 84, Iss , Pp 101942- (2024)
Objective: Hepatic glucose metabolism is profoundly perturbed by excessive alcohol intake. miR-141/200c expression is significantly induced by chronic ethanol feeding. This study aimed at identifying the role of miR-141/200c in glucose homeostasis du
Externí odkaz:
https://doaj.org/article/7b3dd261ae26429d8804416def3b97f6
Publikováno v:
Hepatology Communications, Vol 4, Iss 4, Pp 504-517 (2020)
Liver regeneration requires intrahepatic and extrahepatic metabolic reprogramming to meet the high hepatic bioenergy demand for liver cell repopulation. This study aims to elucidate how pyruvate dehydrogenase kinase 4 (PDK4), a critical regulator of
Externí odkaz:
https://doaj.org/article/fe17191a42944b99b79a286efe1a2581
Publikováno v:
Cells, Vol 11, Iss 17, p 2762 (2022)
The TGF-β/Smad3 signaling pathway is an important process in the pathogenesis of kidney fibrosis. However, the molecular mechanisms are not completely elucidated. The current study examined the functional role of S100A4 in regulating TGF-β/Smad3 si
Externí odkaz:
https://doaj.org/article/ad639f9f112945d2ac42cf0249b3bb11
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
A hallmark of chronic kidney disease is renal fibrosis, which can result in progressive loss of kidney function. Currently, there is no effective therapy for renal fibrosis. Therefore, there is an urgent need to identify potential drug targets for re
Externí odkaz:
https://doaj.org/article/812b228935ae49288f683f61e4dbce97
Publikováno v:
Cells, Vol 11, Iss 5, p 772 (2022)
Inflammatory cells contribute to the pathogenesis of renal ischemia-reperfusion injury (IRI). However, the signaling mechanisms underlying the infiltration of inflammatory cells into the kidney are not well understood. In this study, we examined the
Externí odkaz:
https://doaj.org/article/83c7acea711f44b590ab5e7efc1f810a
Publikováno v:
Hepatology Communications, Vol 2, Iss 7, Pp 765-777 (2018)
The nuclear receptor superfamily contains important transcriptional regulators that play pleiotropic roles in cell differentiation, development, proliferation, and metabolic processes to govern liver physiology and pathology. Many nuclear receptors a
Externí odkaz:
https://doaj.org/article/c431faa9663347e88d2420f92c6a527e
Publikováno v:
Cells, Vol 10, Iss 11, p 3057 (2021)
Renal fibrosis is a pathologic feature of chronic kidney disease, which can lead to end-stage kidney disease. Myeloid fibroblasts play a central role in the pathogenesis of renal fibrosis. However, the molecular mechanisms pertaining to myeloid fibro
Externí odkaz:
https://doaj.org/article/956a7271639a4c33a89b11514efe8814
Autor:
H. Cristina Geiger, David K. Geiger, William R. Roberts, Dominic L. Morell, Paul Huttunen, Jennifer L. Schulman, Melanie Tran, Dori Farthing
Publikováno v:
Gels, Vol 4, Iss 2, p 34 (2018)
Because the factors favoring the formation of well-formed single crystals are dissimilar to those conducive to gel formation, few examples of single-crystal structural characterizations of organogelators are found in the literature. A series of biphe
Externí odkaz:
https://doaj.org/article/408becde789e4417abeb15a1b084277c
Autor:
Melanie Tran, Linda A Gallo, Glenn D Wadley, Andrew J Jefferies, Karen M Moritz, Mary E Wlodek
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e45188 (2012)
There is a strong inverse relationship between a females own birth weight and her subsequent risk for gestational diabetes with increased risk of developing diabetes later in life. We have shown that growth restricted females develop loss of glucose
Externí odkaz:
https://doaj.org/article/d64ceb41f27446fd91d917e50f3be801
Autor:
Melanie Tran, Linda A. Gallo, Glenn D. Wadley, Andrew J. Jefferies, Karen M. Moritz, Mary E. Wlodek
Publikováno v:
PLoS ONE, Vol 7, Iss 11 (2012)
Externí odkaz:
https://doaj.org/article/07b6edfb5a47450eb967f5df07a8e240