Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Melanie Schaper"'
Autor:
Shuya Liu, Yu Zhao, Shun Lu, Tianran Zhang, Maja T. Lindenmeyer, Viji Nair, Sydney E. Gies, Guochao Wu, Robert G. Nelson, Jan Czogalla, Hande Aypek, Stephanie Zielinski, Zhouning Liao, Melanie Schaper, Damian Fermin, Clemens D. Cohen, Denis Delic, Christian F. Krebs, Florian Grahammer, Thorsten Wiech, Matthias Kretzler, Catherine Meyer-Schwesinger, Stefan Bonn, Tobias B. Huber
Publikováno v:
Genome Medicine, Vol 15, Iss 1, Pp 1-19 (2023)
Abstract Background Diabetic nephropathy (DN) is the leading cause of end-stage renal disease, and histopathologic glomerular lesions are among the earliest structural alterations of DN. However, the signaling pathways that initiate these glomerular
Externí odkaz:
https://doaj.org/article/df3b8422c172486d90e70dad5e72e7ce
Autor:
Francisco Rodriguez-Frías, David Tabernero, Josep Quer, Juan I Esteban, Israel Ortega, Esteban Domingo, Maria Cubero, Sílvia Camós, Carles Ferrer-Costa, Alex Sánchez, Rosendo Jardí, Melanie Schaper, Maria Homs, Damir Garcia-Cehic, Jaume Guardia, Rafael Esteban, Maria Buti
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e37874 (2012)
BACKGROUND: Selection of amino acid substitutions associated with resistance to nucleos(t)ide-analog (NA) therapy in the hepatitis B virus (HBV) reverse transcriptase (RT) and their combination in a single viral genome complicates treatment of chroni
Externí odkaz:
https://doaj.org/article/dcd4c83df13542d695ed209d09ece75d
Autor:
Francisco Rodriguez-Frias, Mayra J. Sanchez, Maria Homs, M. Buti, David Tabernero, Melanie Schaper, R. Jardi, Rafael Esteban
Publikováno v:
Alimentary Pharmacology & Therapeutics. 32:97-104
Aliment Pharmacol Ther 2010; 32: 97–104 Summary Background Some patients continue to have detectable HBV-DNA levels with liver disease progression after hepatitis B e antigen (HBeAg) loss. It is important to identify these patients, candidates for
Autor:
Maria Homs, Francisco Rodriguez-Frias, Rafael Esteban, David Tabernero, Melanie Schaper, Rosendo Jardi, Maria Buti, Elena Giggi
Publikováno v:
Journal of Hepatology. 49:695-701
Background/Aims The frequency of mixed hepatitis B virus (HBV) genotypes in chronic HBV (CHB) and genotype changes during natural disease evolution and as a result of antiviral therapy were investigated. Methods Serum samples from 103 CHB patients we
Autor:
Auristela Valdes, R. Jardi, Jaume Guardia, R. Esteban, María Martell, Francisco Rodriguez-Frias, E. Hermosilla, Helena Allende, Melanie Schaper, M. Buti
Publikováno v:
Journal of Viral Hepatitis. 13:343-350
Summary. This study aims to determine the prevalence of hepatitis B virus (HBV) genotypes (A–F) and their association with the G1896A precore mutation in 486 patients positive for HBV surface antigen. Genotypes were determined by RFLP and precore m
Autor:
Jaume Guardia, Auristela Valdes, R. Esteban, R. Jardi, Melanie Schaper, M. Buti, Francisco Rodriguez-Frias
Publikováno v:
Alimentary Pharmacology and Therapeutics. 21:1349-1356
Summary Background : Lamivudine therapy for chronic hepatitis B has been associated with changes in different regions of the hepatitis B virus nucleotide sequence. Aim : To study changes in the sequences of polymerase and precore/core promoter region
Autor:
Auristela Valdes, Rosend Jardi, Rosina Girones, Meritxell Formiga-Cruz, Francisco Rodriguez-Frias, Melanie Schaper, Rafael Esteban, Pilar Clemente-Casares, Maria Buti
Publikováno v:
Journal of Hepatology. 41:126-131
Background/Aims In industrialized countries hepatitis E virus (HEV) infection is rare and its diagnosis is difficult because the utility of available tests is not well established. Methods We studied the presence of acute HEV infection markers in a c
Autor:
Francisco Rodríguez, Rafael Esteban, Auristela Valdes, Rosendo Jardi, Melanie Schaper, Maria Buti, Xose Costa, Jaime Guardia, Helena Allende, Roman Galimany
Publikováno v:
Journal of Hepatology. 40:507-514
Background/Aims : To determine the prevalence and significance of hepatitis B virus (HBV) basic core promoter (BCP) mutations and to establish their relationship with precore (preC) mutations, HBV genotypes and HBV-DNA levels. Methods : BCP and preC
Autor:
Rafael Esteban, Maria Buti, Francisco Rodriguez-Frias, Jaime Guardia, Rosendo Jardi, Melanie Schaper, Mariano Martinez, Auristela Valdes
Publikováno v:
Hepatology. 40:133-139
The purpose of this study was to assess the use of dried blood spot (DBS) samples for hepatitis B virus (HBV) DNA quantification, HBV genotyping, and detection of G1896A precore mutants and variants in the YMDD polymerase motif. We studied DBS and se
Autor:
Joan Jofre, Melanie Schaper
Publikováno v:
Journal of Virological Methods. 89:1-10
The performance of Salmonella typhimurium WG49 and Escherichia coli HS(pFamp)R was compared on detecting the different genotypes of F-specific RNA bacteriophages by plaque hybridisation. The sensitivity of this assay was also compared with the sensit