Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Melanie Ruf"'
Autor:
Peter Schraml, Holger Moch, Tullio Sulser, Maries van den Broek, Cédric Poyet, Thomas Hermanns, Arndt Hartmann, Anna M. Nowicka, Christiane Mittmann, Melanie Ruf
A) Western blot of HIF1α, HIF2α and CD70 in SLR22 after silencing of HIF1α, HIF2α or both together for 48 h and 72 h. B) Western blot of HIF2α and CD70 in SLR24 and C) SLR22 after transient overexpression of HIF2α and D) in A498 and E) SLR22 af
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12e2b84f0c42b77f986668c107624cd7
https://doi.org/10.1158/1078-0432.22460595.v1
https://doi.org/10.1158/1078-0432.22460595.v1
Autor:
Peter Schraml, Holger Moch, Tullio Sulser, Maries van den Broek, Cédric Poyet, Thomas Hermanns, Arndt Hartmann, Anna M. Nowicka, Christiane Mittmann, Melanie Ruf
Supplementary table S1: Antibodies used for Western blot analysis, immunohistochemistry and ChIP. Supplementary table S2: VHL and HIF1α mutation states in cell lines. Supplementary table S3: Primers used for ChIP analysis. Supplementary table S4: Co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50ea2a52b28c33c40d0f699502f52d09
https://doi.org/10.1158/1078-0432.22460583
https://doi.org/10.1158/1078-0432.22460583
Publikováno v:
International Journal of Cancer. 139:396-403
In our study, we demonstrate that ccRCC cell lines with impaired function of pVHL to degrade HIFα express elevated levels of PD-L1. In vitro analysis provided evidence that both reconstitution of pVHL and silencing of HIF2α, but not of HIF1α, lead
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b0f424905b5ad7c8ad314f892825945
https://doi.org/10.1002/ijc.30077
https://doi.org/10.1002/ijc.30077
Autor:
Silvia Casagrande, Markus Rechsteiner, Wilhelm Krek, Laura Morra, Adriana von Teichman, Holger Moch, Peter Schraml, Melanie Ruf, Sonja Brun-Schmid
Publikováno v:
The Journal of Pathology. 229:525-534
Mass spectrometry analysis of renal cancer cell lines recently suggested that the protein-tyrosine phosphatase receptor type J (PTPRJ), an important regulator of tyrosine kinase receptors, is tightly linked to the von Hippel-Lindau protein (pVHL). Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ec14debd8e560e1fe0787d6e500d4c0
https://doi.org/10.1002/path.4107
https://doi.org/10.1002/path.4107
Publikováno v:
Oncoimmunology
CD70 upregulation by hypoxia-inducible factor and CD27(+) lymphocyte tumor infiltration are associated with worse survival in von Hippel-Lindau gene (VHL) mutated clear cell renal cell carcinoma (ccRCC). CD70/CD27 interaction is accompanied by high s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::187b825618604ca4e27374f52d256919
https://europepmc.org/articles/PMC4635726/
https://europepmc.org/articles/PMC4635726/
Autor:
Cédric Poyet, Anna M. Nowicka, Melanie Ruf, Arndt Hartmann, Christiane Mittmann, Maries van den Broek, Peter Schraml, Thomas Hermanns, Holger Moch, Tullio Sulser
Publikováno v:
Clinical Cancer Research
Purpose: CD70, a member of the TNF ligand superfamily, has been shown frequently overexpressed in clear cell renal cell carcinoma (ccRCC). The mechanisms of CD70′s upregulation and its role in ccRCC are unknown. Experimental Design: CD70 expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::970fe673e6e0c81fc31e06d264525f35
https://doi.org/10.5167/uzh-111400
https://doi.org/10.5167/uzh-111400
Publikováno v:
Epidemiologia, Vol 3, Iss 1, Pp 135-147 (2022)
New Zealand has long been praised for the effectiveness of its COVID-19 elimination strategy. It resulted in fewer COVID-19-related deaths, better economic recovery, and less stringent policy measures within its borders compared with other OECD count
Externí odkaz:
https://doaj.org/article/c549e21f826f45369a8853eead65e649
Autor:
Silvia, Casagrande, Melanie, Ruf, Markus, Rechsteiner, Laura, Morra, Sonja, Brun-Schmid, Adriana, von Teichman, Wilhelm, Krek, Peter, Schraml, Holger, Moch
Publikováno v:
The Journal of pathology. 229(4)
Mass spectrometry analysis of renal cancer cell lines recently suggested that the protein-tyrosine phosphatase receptor type J (PTPRJ), an important regulator of tyrosine kinase receptors, is tightly linked to the von Hippel-Lindau protein (pVHL). Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::aa0cec89e0c880404fc3277de87b6e0b
https://pubmed.ncbi.nlm.nih.gov/23007793
https://pubmed.ncbi.nlm.nih.gov/23007793