Homology between human Chromosome 2p13.3 and the wobbler critical region on mouse Chromosome 11: comparative high-resolution mapping of STS and EST loci on YAC/BAC contigs

Autor: Dirk Korthaus, Cora S. Thiel, Harald Jockusch, Karin Resch, Thomas Schmitt-John, Melanie Ronsiek, Niels Wedemeyer, Kristin Baer, Andreas Lengeling

Publikováno v: Mammalian Genome. 9:893-898

Human Chr 2p13-14 and homologous regions on mouse Chrs 6 and 11 have been subjects of previous studies because they comprise the loci for several neuromuscular diseases. Here we report on high-resolution mapping of 55 STS and EST loci on human Chr 2p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::006c3ead05b96f57e2111f1fd6a1faa4
https://doi.org/10.1007/s003359900890

Genetic modifiers that aggravate the neurological phenotype of the wobbler mouse

Autor: Melanie Ronsiek, Anke Mussmann, Harald Jockusch, Volker C. Schmidt, Michael Ulbrich, Martin Augustin, Jörg W. Bartsch, Thomas Schmitt-John

Publikováno v: Ulbrich, M, Schmidt, V, Ronsiek, M, Mussmann, A, Bartsch, J, Augustin, M, Jockusch, H & Schmitt-John, T 2002, ' Genetic modifiers that aggravate the neurological phenotype of the wobbler mouse ', NeuroReport, vol. 13, pp. 535-539 .

The autosomal recessive mutation wobbler of the mouse (phenotype WR; genotype wr/wr) causes muscular atrophy due to motoneuron degeneration with 100% penetrance on the standard Mus musculus laboratorius C57BL/6J background. In inter- and backcrosses

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0641175d1f130131b6d06e2f57a55037
https://doi.org/10.1097/00001756-200203250-00035

Dynamin genes Dnm1 and Dnm2 are located on proximal mouse chromosomes 2 and 9, respectively

Autor: Melanie Ronsiek, Rainer Klocke, André Augustin, Herman van der Putten, Aribert Stief, Harald Jockusch

Publikováno v: Genomics. 41(2)

Dynamins, microtubule-binding GTPases, are encoded by at least three genes in mammals. Two distinct gene-specific cDNAs were used to analyze the segregation of dynamin genes Dnm1 and Dnm2 in a mouse interspecies backcross. The nervous system expresse

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c74ee8a0a2d3934520d6b0033b7fdd0b
https://pubmed.ncbi.nlm.nih.gov/9143510

YAC contigs of the Rab1 and wobbler (wr) spinal muscular atrophy gene region on proximal mouse chromosome 11 and of the homologous region on human chromosome 2p

Autor: Melanie Ronsiek, Harald Jockusch, Andreas Lengeling, Niels Wedemeyer, Dirk Korthaus, Martina Wuttke, Kristin Baer

Publikováno v: Wedemeyer, N, Lengeling, A, Ronsiek, M, Korthaus, D, Baer, K, Wuttke, M & Jockusch, H 1996, ' YAC contigs of the Rab1 and wobbler (wr) spinal muscular atrophy gene region on proximal mouse chromosome 11 and of the homologous region on human chromosome 2p ', Genomics, vol. 32, no. 3, pp. 447-54 . https://doi.org/10.1006/geno.1996.0140

Despite rapid progress in the physical characterization of murine and human genomes, little molecular information is available on certain regions, e.g., proximal mouse chromosome 11 (Chr 11) and human chromosome 2p (Chr 2p). We have localized the wob

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d35d7e10f98fc1e94270a2ff09b64c4c
https://hdl.handle.net/20.500.11820/6e903f39-f1ac-4e99-a012-fd2195f13e44

Interaction of plant profilin with mammalian actin

Autor: Martin Rothkegel, Hans-Georg Mannherz, Melanie Ronsiek, Brigitte M. Jockusch, Rudolf Valenta, Klaudia Giehl

Publikováno v: European journal of biochemistry. 226(2)

The mode of interaction of birch and bovine profilins with actin was compared using a number of techniques. Birch profilin was purified from pollen or as a recombinant protein from Escherichia coli, using poly(l-proline) affinity chromatography and a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::366d172ffb7a08044d0af9f75448f237
https://pubmed.ncbi.nlm.nih.gov/8001585