Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Melanie Röth"'
Autor:
Roland Beckmann, Kristian Jensen, Sebastian Fenn, Janina Speck, Katrin Krause, Anastasia Meier, Melanie Röth, Sascha Fauser, Raymond Kimbung, Derek T. Logan, Martin Steegmaier, Hubert Kettenberger
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Bispecific antibodies can bind to two distinct targets though the fusion of two different Fv regions. In this study, the authors develop DutaFabs that present two separated and independent antigen binding sites within the same Fv region, giving rise
Externí odkaz:
https://doaj.org/article/70c0f8f5eaae4c48be3ad457ee0a7a4b
Autor:
Sascha Fauser, Janina Speck, Derek T. Logan, Hubert Kettenberger, Roland Beckmann, Sebastian Fenn, Katrin Krause, Melanie Röth, Raymond Kimbung, Kristian Jensen, Martin Steegmaier, Anastasia Meier
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
We report the development of a platform of dual targeting Fab (DutaFab) molecules, which comprise two spatially separated and independent binding sites within the human antibody CDR loops: the so-called H-side paratope encompassing HCDR1, HCDR3 and L
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e0f855cacf1604af53f03c7d3549995
http://europepmc.org/articles/PMC7846786
http://europepmc.org/articles/PMC7846786
Autor:
Zeribe C. Nwosu, Nadia Battello, Melanie Rothley, Weronika Piorońska, Barbara Sitek, Matthias P. Ebert, Ute Hofmann, Jonathan Sleeman, Stefan Wölfl, Christoph Meyer, Dominik A. Megger, Steven Dooley
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 37, Iss 1, Pp 1-15 (2018)
Abstract Background Although metabolism is profoundly altered in human liver cancer, the extent to which experimental models, e.g. cell lines, mimic those alterations is unresolved. Here, we aimed to determine the resemblance of hepatocellular carcin
Externí odkaz:
https://doaj.org/article/61f1eaa6aaf640baaea83325cd0e8c8e
Autor:
Caroline Schreiber, Supriya Saraswati, Shannon Harkins, Annette Gruber, Natascha Cremers, Wilko Thiele, Melanie Rothley, Diana Plaumann, Claudia Korn, Olivier Armant, Hellmut G Augustin, Jonathan P Sleeman
Publikováno v:
PLoS Genetics, Vol 15, Iss 6, p e1008216 (2019)
ASAP1 is a multi-domain adaptor protein that regulates cytoskeletal dynamics, receptor recycling and intracellular vesicle trafficking. Its expression is associated with poor prognosis for a variety of cancers, and promotes cell migration, invasion a
Externí odkaz:
https://doaj.org/article/dda25dc10fb74d3d87b9cf2c4d31dbaf
Publikováno v:
Glossa, Vol 3, Iss 1 (2018)
This special collection brings together research exploring and evaluating probabilistic variation patterns from a comparative perspective, thus highlighting current work situated at the crossroads of research on usage-based theoretical linguistics, v
Externí odkaz:
https://doaj.org/article/9db9896014f740428a0c458a0ffe86c5
Autor:
Natascha Cremers, Antje Neeb, Tanja Uhle, Arno Dimmler, Melanie Rothley, Heike Allgayer, Riccardo Fodde, Jonathan Paul Sleeman, Wilko Thiele
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0151468 (2016)
CD24 is a small, heavily glycosylated, GPI-linked membrane protein, whose expression has been associated with the tumorigenesis and progression of several types of cancer. Here, we studied the expression of CD24 in tumors of MMTV-PyMT, Apc1572/T+ and
Externí odkaz:
https://doaj.org/article/5d17e61772cf44eba61f3f6aebfa4b6d
Autor:
Zeribe C. Nwosu, Nadia Battello, Melanie Rothley, Weronika Piorońska, Barbara Sitek, Matthias P. Ebert, Ute Hofmann, Jonathan Sleeman, Stefan Wölfl, Christoph Meyer, Dominik A. Megger, Steven Dooley
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 37, Iss 1, Pp 1-1 (2018)
In the publication of this article (1), there is an error in Fig. 5b. This has now been updated in the original article (1).
Externí odkaz:
https://doaj.org/article/deeae198ae5a475aa13547e53b62e398
Publikováno v:
OENO One, Vol 44, Iss 3, Pp 151-159 (2010)
Aim: The present work evaluated different strategies for the control of grey mold, caused by Botrytis cinerea, on wine grapes, including the use of the plant growth regulator Gibb3, leaf removal and/or botryticide treatments. The efficiency of the di
Externí odkaz:
https://doaj.org/article/c5b8ca804d174e4bb6d67981fa17286b