Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Melanie Röth"'
Autor:
Roland Beckmann, Kristian Jensen, Sebastian Fenn, Janina Speck, Katrin Krause, Anastasia Meier, Melanie Röth, Sascha Fauser, Raymond Kimbung, Derek T. Logan, Martin Steegmaier, Hubert Kettenberger
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Bispecific antibodies can bind to two distinct targets though the fusion of two different Fv regions. In this study, the authors develop DutaFabs that present two separated and independent antigen binding sites within the same Fv region, giving rise
Externí odkaz:
https://doaj.org/article/70c0f8f5eaae4c48be3ad457ee0a7a4b
Autor:
Sascha Fauser, Janina Speck, Derek T. Logan, Hubert Kettenberger, Roland Beckmann, Sebastian Fenn, Katrin Krause, Melanie Röth, Raymond Kimbung, Kristian Jensen, Martin Steegmaier, Anastasia Meier
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
We report the development of a platform of dual targeting Fab (DutaFab) molecules, which comprise two spatially separated and independent binding sites within the human antibody CDR loops: the so-called H-side paratope encompassing HCDR1, HCDR3 and L
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e0f855cacf1604af53f03c7d3549995
http://europepmc.org/articles/PMC7846786
http://europepmc.org/articles/PMC7846786
Autor:
Beckmann, Roland, Jensen, Kristian, Fenn, Sebastian, Speck, Janina, Krause, Katrin, Meier, Anastasia, Röth, Melanie, Fauser, Sascha, Kimbung, Raymond, Logan, Derek T., Steegmaier, Martin, Kettenberger, Hubert
Publikováno v:
Nature Communications; 1/29/2021, Vol. 12 Issue 1, p1-13, 13p
Autor:
Fischer, Jens A. A., Hueber, Axel J., Wilson, Stacy, Galm, Margarete, Baum, Wolfgang, Kitson, Christopher, Auer, Johannes, Lorenz, Stefan H., Moelleken, Jörg, Bader, Martin, Tissot, Alain C., Tan, Seng‐Lai, Seeber, Stefan, Schett, Georg
Publikováno v:
Arthritis & Rheumatology; Jan2015, Vol. 67 Issue 1, p51-62, 12p