Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Melanie Prescott"'
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
IntroductionPolycystic ovary syndrome (PCOS) is the most common infertility disorder worldwide, typically characterised by high circulating androgen levels, oligo- or anovulation, and polycystic ovarian morphology. Sexual dysfunction, including decre
Externí odkaz:
https://doaj.org/article/79da1538b240400c872e64c5a4078e0f
Autor:
Mauro S.B. Silva, Elodie Desroziers, Sabine Hessler, Melanie Prescott, Chris Coyle, Allan E. Herbison, Rebecca E. Campbell
Publikováno v:
EBioMedicine, Vol 44, Iss , Pp 582-596 (2019)
Background: Enhanced GABA activity in the brain and a hyperactive hypothalamic-pituitary-gonadal axis are associated with polycystic ovary syndrome (PCOS), the most common form of anovulatory infertility. Women with PCOS exhibit elevated cerebrospina
Externí odkaz:
https://doaj.org/article/04e185871f794c2aa414df5e6871c075
Publikováno v:
Journal of neuroendocrinology. 34(4)
Polycystic ovary syndrome (PCOS) is associated with androgen excess and, frequently, hyperactive pulsatile luteinizing hormone (LH) secretion. Although the origins of PCOS are unclear, evidence from pre-clinical models implicates androgen signalling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1440a161381a32221dfe85b7c3c038b2
https://pubmed.ncbi.nlm.nih.gov/35267218
https://pubmed.ncbi.nlm.nih.gov/35267218
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports
Scientific Reports
Prenatal androgen excess is suspected to contribute to the development of polycystic ovary syndrome (PCOS) in women. Evidence from preclinical female animal models links maternal androgen excess with the development of PCOS-like features and associat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb04e3f1f8c66bdedeff560f033f58e4
http://link.springer.com/article/10.1038/s41598-019-55436-9
http://link.springer.com/article/10.1038/s41598-019-55436-9
Publikováno v:
Journal of neuroendocrinologyREFERENCES. 33(12)
Prenatal exposure to excess androgens is associated with the development of polycystic ovary syndrome (PCOS). In prenatally androgenised (PNA) mice, a model of PCOS, progesterone receptor (PR) protein expression is reduced in arcuate nucleus (ARC) GA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::044bdb497cc2f6a9d8c18da62d30c739
https://pubmed.ncbi.nlm.nih.gov/34748236
https://pubmed.ncbi.nlm.nih.gov/34748236
Autor:
Rebecca Campbell, Christopher J Marshall, Melanie Prescott, Sabine Hessler, Allan E. Herbison, Eulalia A. Coutinho
Publikováno v:
Neuroendocrinology. 110:671-687
Introduction: The central regulation of fertility is carefully coordinated with energy homeostasis, and infertility is frequently the outcome of energy imbalance. Neurons in the hypothalamus expressing neuropeptide Y and agouti-related peptide (NPY/A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0444f5d8f6167cd5316c4e91226b4c7
https://doi.org/10.1159/000504225
https://doi.org/10.1159/000504225
Autor:
Chris Coyle, Mauro S.B. Silva, Rebecca Campbell, Elodie Desroziers, Allan E. Herbison, Sabine Hessler, Melanie Prescott
Publikováno v:
EBioMedicine. 44:582-596
Background Enhanced GABA activity in the brain and a hyperactive hypothalamic-pituitary-gonadal axis are associated with polycystic ovary syndrome (PCOS), the most common form of anovulatory infertility. Women with PCOS exhibit elevated cerebrospinal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b6dde7de86c4b334605d23752aa0a0c
https://doi.org/10.1016/j.ebiom.2019.05.065
https://doi.org/10.1016/j.ebiom.2019.05.065
Autor:
Sarah Holland, Christine L. Jasoni, Aisha Sati, Rebecca Campbell, Melanie Prescott, Elodie Desroziers
Publikováno v:
Journal of neuroendocrinologyREFERENCES. 33(8)
Although polycystic ovary syndrome (PCOS) is the most common cause of anovulatory infertility worldwide, the aetiology of the disorder remains poorly defined. Animal-based evidence highlights the brain as a prime suspect in both the development and m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c50c270ab9d55f368ed0dafb93fed064
https://pubmed.ncbi.nlm.nih.gov/34216402
https://pubmed.ncbi.nlm.nih.gov/34216402