Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Melanie Picciano"'
Autor:
Yasuji Matsuoka, Miquel Vila, Sarah Lincoln, Alison McCormack, Melanie Picciano, John LaFrancois, Xin Yu, Dennis Dickson, William J. Langston, Eileen McGowan, Matt Farrer, John Hardy, Karen Duff, Serge Przedborski, Donato A. Di Monte
Publikováno v:
Neurobiology of Disease, Vol 8, Iss 3, Pp 535-539 (2001)
α-Synuclein has been identified as a major component of Lewy body inclusions, which are one of the pathologic hallmarks of idiopathic Parkinson's disease. Mutations in α-synuclein have been found to be responsible for rare familial cases of Parkins
Externí odkaz:
https://doaj.org/article/8e2813da0f1045a4bb948bd73bb938d0
Autor:
John LaFrancois, Alison L. McCormack, Melanie Picciano, Yasuji Matsuoka, Karen Duff, Serge Przedborski, Eileen McGowan, John Hardy, Sarah Lincoln, Miquel Vila, Xin Yu, Dennis W. Dickson, Donato A. Di Monte, William J. Langston, Matthew J. Farrer
Publikováno v:
Neurobiology of Disease, Vol 8, Iss 3, Pp 535-539 (2001)
alpha-Synuclein has been identified as a major component of Lewy body inclusions, which are one of the pathologic hallmarks of idiopathic Parkinson's disease. Mutations in alpha-synuclein have been found to be responsible for rare familial cases of P
Publikováno v:
Neuroscience. 104:609-613
Beta-amyloid is one of the most significant features of Alzheimer's disease, and has been considered to play a pivotal role in neurodegeneration through an unknown mechanism. However, it has been noted that beta-amyloid accumulation is associated wit
Autor:
Benjamin H. Kao, Melanie Picciano, Jochen Walter, Paul M. Mathews, David Nochlin, Athena Andreadis, Anne M. Cataldo, Xi Qin, Ying Jiang, Christian Haass, John L. Yang, Ralph A. Nixon, Carol F. Lippa, Lyne Levesque, Thomas D. Bird, Paul E. Fraser, Christine M. Hulette, Anna G. Rudnicki
Publikováno v:
Molecular Medicine. 6:878-891
Mutations in the presenilin proteins cause early-onset, familial Alzheimer’s disease (FAD). We characterized the cellular localization and endoproteolysis of presenilin 2 (PS2) and presenilin 1 (PS1) in brains from 25 individuals with presenilin-mu
Autor:
M. Kerry O'Banion, Karen Duff, John LaFrancois, Yasuji Matsuoka, JoAnna M. Daeschner, Brian Malester, Melanie Picciano, Andrea J. Tenner, Cynthia A. Lemere, Cindy Zehr, Maria I. Fonseca, John A. Olschowka
Mutations in the amyloid precursor protein (APP) and presenilin-1 and -2 genes (PS-1, -2) cause Alzheimer's disease (AD). Mice carrying both mutant genes (PS/APP) develop AD-like deposits composed of beta-amyloid (Abeta) at an early age. In this stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6dabd2cb829f0d76fb63c6a4e77a86d
https://europepmc.org/articles/PMC1891893/
https://europepmc.org/articles/PMC1891893/
Publikováno v:
Neurobiology of Aging. 21:18