Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Melanie Nyuydzefe"'
Autor:
Alexandra Zanin-Zhorov, Wei Chen, Melanie Nyuydzefe, Julien Moretti, Iris Zhorov, Rashmi Munshi, Malavika Ghosh, Kelli MacDonald, Bruce Blazar, Sam Waksal
Publikováno v:
Journal of Hepatology. 77:S494-S495
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d809f8fa669d1843a8655bc04287198c
https://doi.org/10.1016/s0168-8278(22)01319-8
https://doi.org/10.1016/s0168-8278(22)01319-8
Autor:
Alexandra Zanin-Zhorov, Jonathan M Weiss, Alyssa Trzeciak, Wei Chen, Jingya Zhang, Melanie Nyuydzefe, Carmen Arencibia, Seetharam Polimera, Judilyn Fuentes-Duculan, Kathleen Bonifacio, Norma Kunjravia, Inna Cueto, Mark Berger, James Krueger, John L Ryan, Samuel D Waksal
Publikováno v:
The Journal of Immunology. 198:197.3-197.3
Targeted inhibition of Rho-associated kinase 2 (ROCK2) down-regulates pro-inflammatory T-cell response, while increasing the regulatory arm of immune response in animals models of autoimmunity and T helper 17 (Th17)-skewing human cell culture in vitr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e4f7c189e99626128661dbe76c458f1
https://doi.org/10.4049/jimmunol.198.supp.197.3
https://doi.org/10.4049/jimmunol.198.supp.197.3
Autor:
Jonathan Weiss, Wei Chen, melanie Nyuydzefe, Ryan Flynn, James Tonra, Suzana Marusic, Bruce Blazar, Samuel Waksal, Alexandra Zanin-Zhorov
Publikováno v:
The Journal of Immunology. 194:121.7-121.7
PD1+CXCR5+ T follicular helper (Tfh) cells are essential for generating high-affinity antibodies and B cell memory. But aberrant Tfh activity can drive autoimmune disease such as systemic lupus erythematosus (SLE) which is characterized by high level
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dbcda19af7c9f5cab1c81f005f4cf07a
https://doi.org/10.4049/jimmunol.194.supp.121.7
https://doi.org/10.4049/jimmunol.194.supp.121.7
Autor:
Alexandra Zanin-Zhorov, Ryan Flynn, Leo Luznik, melanie Nyuydzefe, Angela Panoskaltsis-Mortari, Jing Du, Katelyn Goodman, Jonathan Weiss, Wei Chen, Jonathan Serody, Kelli MacDonald, Geoffrey Hill, John O'Shea, Samuel Waksal, Bruce Blazar
Publikováno v:
The Journal of Immunology. 194:140.15-140.15
Rho-associated kinase 2 (ROCK2) was recently shown to be implicated in regulation of IL-21 and IL-17 secretion in mice and humans. Here, we report that the potent and highly selective ROCK2 inhibitor KD025 effectively reverses an established chronic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3db3ae098bf8193db4716e39e1e19a6c
https://doi.org/10.4049/jimmunol.194.supp.140.15
https://doi.org/10.4049/jimmunol.194.supp.140.15
Autor:
Alexandra Zanin-Zhorov, Rigen Mo, Jose Scher, Melanie Nyuydzefe, Jonathan Weiss, Olivier Schueller, Sara Weiss, Masha Poyurovsky, Michael Dustin, Steven Abramson, Samuel Waksal
Publikováno v:
The Journal of Immunology. 192:63.3-63.3
Targeting pro-inflammatory cytokines is a promising approach to the treatment of certain autoimmune diseases. However, the signaling mechanisms involved in the initiation and effector phases of auto-aggressive pathways are still an enigma. Rho-associ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea654ec9c823744de801bb008df99d9c
https://doi.org/10.4049/jimmunol.192.supp.63.3
https://doi.org/10.4049/jimmunol.192.supp.63.3