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Publikováno v:
CNS Neuroscience & Therapeutics. 24:876-888
BACKGROUND: Alzheimer's disease (AD) is a neurodegenerative disorder that affects over 45 million people worldwide. Patients with severe AD require help with daily activities and show severe memory impairment. Currently, donepezil is one of two drugs
Autor:
Avril Hatherell, Benedict C. Albensi, Michael J. Bernstein, Melanie Neuendorff, Kensuke Oikawa, Eric Platt, Gary L. Odero
Publikováno v:
BMC Neuroscience
BMC Neuroscience, Vol 13, Iss 1, p 45 (2012)
BMC Neuroscience, Vol 13, Iss 1, p 45 (2012)
Background Nuclear factor kappa B (NF-κB) is a transcription factor typically expressed with two specific subunits (p50, p65). Investigators have reported that NF-κB is activated during the induction of in vitro long term potentiation (LTP), a para